Top Senior Python Jobs in Boston, MA

Design and develop scalable software applications in Python, collaborate with teams, and ensure code quality for critical defense projects.

Lead a team to develop distributed systems using Golang and Python on Kubernetes, collaborate on AI/ML solutions, and drive technological innovation.

Lead a team of developers to build technology projects using microservices and full stack systems, focusing on cloud-based solutions and mentoring team members.

Lead diverse technology projects in distributed microservices and full stack systems, mentoring team members and collaborating with product managers on cloud-based solutions.

The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.

Lead a portfolio of technology projects with a team of developers to create solutions for regulatory needs, collaborating on cloud-based projects while mentoring engineers.

The Principal Python Backend Engineer will design and build high-performance backend systems for AI/ML services, focus on clean code, maintainability, and automation, while leading teams through a collaborative and innovative approach.

Lead end-to-end feature development for a new AI-driven life sciences SaaS platform: design, implement, deploy, support, and mentor engineers. Collaborate with product and development teams, enforce engineering best practices, perform expert code reviews, and scale the product for high-volume enterprise use while using AI-assisted engineering tools.

Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.

The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.

The Principal Python Engineer will design, build, and maintain backend services and APIs, focusing on system reliability and engineering quality. The role involves working with databases, applying DevOps practices, and leveraging AI for development efficiency.

The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.

Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.

Join the Trading Engine team to develop and maintain client-facing open-source libraries, act as an SME for REST and WebSocket trading APIs, and work directly with large clients to design and optimize trading algorithms and integrations.

Design, build, test, and maintain backend applications using FastAPI and SQLAlchemy. Implement database schemas, integrate front-end components, optimize for performance and scalability, debug issues, participate in code reviews, and collaborate on feature design. Maintain clean, testable code and stay current with best practices.

Lead the technical direction for integrating algorithms on the Prism Mapping platform, focusing on real-time signal pipelines and optimization strategies. Collaborate with teams to ensure robust clinical performance and timely delivery of new capabilities.

As a Senior Software Engineer, you'll develop signals and algorithm interfaces, collaborate with developers, optimize algorithms, and mentor engineers in a regulated environment.

Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.

Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.

As a Senior Software Engineer, you'll enhance ClickHouse's Python integrations, drive AI integration strategies, and collaborate with open-source communities, requiring deep expertise in data engineering and AI applications.

The Senior Python Developer will enhance commerce and communication infrastructure by developing features, collaborating with stakeholders, ensuring system reliability, and integrating with third-party tools, while maintaining high-performance standards.

Maintain and improve the LangChain Python package, enhance documentation, assist users, and build example applications.

As a Founding Staff Software Engineer, you will lead the design and development of robust backend systems and APIs, optimize large-scale data workflows, and mentor a growing engineering team.

Design, implement, and scale event-driven, distributed backend systems in Python on AWS to process and enrich large-scale document and media datasets. Lead technical projects, mentor engineers, integrate ML/LLM components, optimize performance, maintain observability, and collaborate with Data Science, ML Engineering, and Product to deliver reliable high-throughput content processing services.

Design, build, and optimize event-driven, distributed backend systems and APIs in Python for large-scale content metadata extraction and enrichment. Deploy and operate resilient AWS-based pipelines, collaborate with ML teams to integrate models, and ensure system performance, observability, and data integrity.