Top Senior Python Jobs in Boston, MA

Design, develop, and maintain scalable, reliable Python applications. Participate in design and code reviews, collaborate with engineers and data scientists, adopt microservices and containerization, follow Agile practices, and support deployment and integration for DoD-focused AI/ML and simulation projects.

The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.

Lead a portfolio of technology projects with a team of developers to create solutions for regulatory needs, collaborating on cloud-based projects while mentoring engineers.

Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.

Lead diverse technology projects in distributed microservices and full stack systems, mentoring team members and collaborating with product managers on cloud-based solutions.

Lead a team to develop distributed systems using Golang and Python on Kubernetes, collaborate on AI/ML solutions, and drive technological innovation.

Lead a team of developers to build technology projects using microservices and full stack systems, focusing on cloud-based solutions and mentoring team members.

The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.

The Principal Python Engineer will design, build, and maintain backend services and APIs, focusing on system reliability and engineering quality. The role involves working with databases, applying DevOps practices, and leveraging AI for development efficiency.

The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.

Develop Python-based solutions performing SQL/CRUD operations, file extraction/transformation/generation (CSV, XML, JSON, PDF), and email integration. Work in an onsite/offshore model, collaborate with teams, communicate clearly, and perform under pressure for contract assignments.

Build and own features for a new AI-driven enterprise SaaS platform for life sciences. Design, develop, deploy, and support production Python services, collaborate on technical design, drive scalability, mentor engineers, and define engineering best practices with AI-assisted workflows.

Design, build, and maintain enterprise-grade Python applications and data-processing systems. Deliver secure, high-performance code, optimize large-scale data workflows, produce architecture artifacts, support production incidents, and mentor engineers while collaborating with product, data, and infrastructure teams.

Maintain and improve the LangChain Python package, enhance documentation, assist users, and build example applications.

Design, implement, and scale event-driven, distributed backend systems in Python on AWS to process and enrich large-scale document and media datasets. Lead technical projects, mentor engineers, integrate ML/LLM components, optimize performance, maintain observability, and collaborate with Data Science, ML Engineering, and Product to deliver reliable high-throughput content processing services.

Lead the technical direction for integrating algorithms on the Prism Mapping platform, focusing on real-time signal pipelines and optimization strategies. Collaborate with teams to ensure robust clinical performance and timely delivery of new capabilities.

As a Senior Software Engineer, you'll develop signals and algorithm interfaces, collaborate with developers, optimize algorithms, and mentor engineers in a regulated environment.

Design, develop, deploy, monitor, and support APIs and system integrations (Salesforce, REST, third-party). Work directly with clients to gather requirements, troubleshoot and optimize integrations, operate solutions in AWS, collaborate with teams, and mentor junior developers.

Build and ship full‑stack features for transportation management and other client products. Design and implement APIs and UIs, collaborate with product and design, own delivery, write modular testable code, troubleshoot and iterate quickly, and mentor peers.

The Forward Deployed Engineer will serve as a technical bridge between clients and engineering teams, writing custom code and integrations, while ensuring customer success with Socket's security platform through strong relationships and expert technical guidance.

Design, implement, and maintain SaaS features using Python and React on AWS. Lead system design, code reviews, CI/CD pipelines, AI-integrated development (LLMs and AI coding agents), prompt engineering, testing (Cypress), and on-call production support. Mentor teammates and ensure secure, scalable, well-documented software.

Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.

The Senior Software Engineer will build a large-scale data ingestion and classification system using web scraping, data processing, and search technologies, overseeing data extraction from various sources and developing search capabilities.

Develop and maintain backend solutions, ensuring performance, security, and regulatory compliance, while collaborating in cross-functional teams.

The Principal Python Backend Engineer will design and build high-performance backend systems for AI/ML services, focus on clean code, maintainability, and automation, while leading teams through a collaborative and innovative approach.