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Top Principal Engineer Jobs in Boston, MA

Reposted 8 Days AgoSaved
In-Office
Boston, MA
300K-500K Annually
Expert/Leader
300K-500K Annually
Expert/Leader
Artificial Intelligence • Information Technology • Software • Generative AI • Automation
The Principal Engineer will take ownership of production-grade systems, improve customer outcomes with high-leverage features, and ensure technical quality across the stack, utilizing deep expertise in backend and AI systems.
Top Skills: AWSAzureCassandraDynamoDBGCPKubernetesMongoDBMySQLNeo4JPostgresPythonTerraform
14 Days AgoSaved
Hybrid
Boston, MA
118K-201K Annually
Senior level
118K-201K Annually
Senior level
Aerospace • Hardware • Information Technology • Security • Software • Cybersecurity • Defense
Design, implement, and maintain C++ tracking and estimation software for ISR and sensor systems. Lead small multidisciplinary teams, manage codebase from requirements through testing, support demonstrations and customer interactions, and work within Agile/DevSecOps environments on Windows and Linux.
Top Skills: AgileCC++DevsecopsEmbedded SystemsGit (Collaborative Source Code Management)LinuxRadar TrackingReal-Time ProcessingSensor FusionTracking And EstimationWindows
Reposted 14 Days AgoSaved
Hybrid
Boston, MA
250K-310K Annually
Expert/Leader
250K-310K Annually
Expert/Leader
Artificial Intelligence • Cloud • Information Technology • Security • Software • Cybersecurity • Data Privacy
The Principal Software Engineer at Snyk will lead technical initiatives, mentor engineers, engage with stakeholders, and influence product strategy, focusing on software security and scalability.
Top Skills: GoTypescript
Reposted 5 Days AgoSaved
Remote
Boston, MA
131K-224K Annually
Senior level
131K-224K Annually
Senior level
Beauty • Robotics • Design • Appliances • Manufacturing
The Principal Electrical Systems Engineer will focus on system architecture, design, and prototyping across electrical and embedded domains, collaborating with cross-functional teams to evaluate emerging technologies and inform product direction.
Top Skills: ArduinoBluetoothEdge AiElectrical SystemsEmbedded SystemsMlPower ElectronicsRaspberry PiSensorsWi-Fi
Reposted 10 Days AgoSaved
Remote or Hybrid
Boston, MA
200K-275K Annually
Senior level
200K-275K Annually
Senior level
Artificial Intelligence • Automotive • Machine Learning • Transportation
Seeking a Principal Engineer to define and govern architecture for the Developer Platform while ensuring technical excellence in build systems and CI/CD practices.
Top Skills: AWSBazelCi/CdCloudFormationDatadogGithub ActionsGitlab CiGoGrafanaNode.jsPrometheusPythonTerraform
Reposted YesterdaySaved
Remote or Hybrid
Boston, MA
200K-285K Annually
Senior level
200K-285K Annually
Senior level
Artificial Intelligence • Automotive • Machine Learning • Transportation
Lead the development of perception capabilities for self-driving vehicles, focusing on computer vision and deep learning to enhance product impact and safety evaluation.
Top Skills: C++CudaPythonPyTorchTensorrt
Reposted YesterdaySaved
Remote
Boston, MA
Senior level
Senior level
Big Data • Marketing Tech • Analytics
Lead architectural vision and technical design for D2C platforms, focusing on AI integration, performance, and scalability while mentoring teams and promoting innovation.
Top Skills: AndroidAngularApi-First DesignAutomation ToolsAWSGithub CopilotGraphQLiOSKotlinMicroservicesReactSduiSwift
11 Days AgoSaved
Easy Apply
In-Office
Boston, MA
Easy Apply
147K-180K Annually
Senior level
147K-180K Annually
Senior level
Biotech
Lead engineering strategy and implementation for cGMP bioprocess and bioconjugation manufacturing. Design, optimize, and scale processes and equipment, develop PAT and automation control strategies, oversee CDMO activities, ensure regulatory compliance, and drive continuous improvement across cross-functional teams.
Top Skills: Pat,Automation,Process Modeling,Control Systems,Real-Time Monitoring,Manufacturing Skids,Continuous Manufacturing,Lean,Six Sigma,Advanced Process Analytics,Scale-Down Model Qualification (Sdmq),Process Characterization,Process Control Strategy (Pcs),Cgmp,Cdmo,Biologics Downstream Purification,Bioconjugation
Reposted 7 Days AgoSaved
Remote
Boston, MA
229K-284K Annually
Senior level
229K-284K Annually
Senior level
Healthtech • Other • Social Impact • Software • Telehealth
The Principal AI Engineer will lead the design and implementation of scalable AI systems in mental healthcare, ensuring safety and reliability while making AI useful in clinical contexts.
Top Skills: AnthropicAWSBedrockDspyFaissGCPGeminiGoHaystackJavaJavaScriptLangchainLlamaindexMilvusOpenaiPineconePythonTypescriptWeaviate
Reposted 7 Days AgoSaved
Remote
Boston, MA
200K-320K Annually
Senior level
200K-320K Annually
Senior level
Cloud • Fintech • Food • Information Technology • Software • Hospitality
As a Principal Software Engineer, you'll architect and code backend services and ML models, integrate them with Salesforce, and mentor junior engineers.
Top Skills: AWSGoJavaLambdaLangchainPythonSagemakerSalesforceSqs
12 Days AgoSaved
Remote or Hybrid
Boston, MA
240K-330K Annually
Expert/Leader
240K-330K Annually
Expert/Leader
Artificial Intelligence • Automotive • Machine Learning • Transportation
Lead R&D of motion planning, trajectory generation, and control algorithms and ML models for autonomous vehicles. Architect systems with cross-functional teams, design simulation and validation for edge cases, document findings for safety traceability, and mentor junior engineers.
Top Skills: C++DdsLinuxPythonRosRust
Reposted 2 Days AgoSaved
In-Office or Remote
Boston, MA
233K-480K Annually
Expert/Leader
233K-480K Annually
Expert/Leader
Social Media
The Principal Engineer will lead technical strategy for ad products, mentor teams, oversee significant engineering projects, and drive innovation in machine learning and advertising technology.
Top Skills: Advertising TechnologyGenerative AiMachine LearningSoftware Engineering
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Reposted 2 Days AgoSaved
Remote
Boston, MA
180K-250K Annually
Expert/Leader
180K-250K Annually
Expert/Leader
Gaming
Lead the design of Xsolla's identity platform, develop Golang microservices for user management, and implement security protocols for compliance.
Top Skills: AWSAzureGCPGoHashicorp VaultKubernetesOauth2OidcSAMLScim
Reposted 12 Days AgoSaved
In-Office or Remote
Boston, MA
150K-155K Annually
Senior level
150K-155K Annually
Senior level
Healthtech • Pharmaceutical
The Sr Principal Engineer guides software design and development for medical devices, resolving complex problems and mentoring junior engineers while adhering to medical regulations.
Top Skills: .Net Core.Net FrameworkAWSAzureC#GCPGitHTTPKubernetesRestSoapSQL ServerVMware
18 Days AgoSaved
Hybrid
Boston, MA
221K-425K Annually
Senior level
221K-425K Annually
Senior level
Blockchain • Fintech • Payments • Consulting • Cryptocurrency • Cybersecurity • Quantum Computing
Lead design and development of high-performance Java-based solutions, architect enterprise integrations, drive performance engineering, mentor developers, own CI/CD and containerization efforts, and represent domain direction externally.
Top Skills: Java Jdk 8+,Tomcat,Spring,Spring Boot,Shell Scripting,Json,Docker,Kubernetes,Junit,Jenkins,Gradle,Maven,Source Control Management,React.Js,Aws
Reposted 8 Days AgoSaved
Easy Apply
Remote or Hybrid
Boston, MA
Easy Apply
300K-400K Annually
Expert/Leader
300K-400K Annually
Expert/Leader
AdTech • Artificial Intelligence • Marketing Tech • Software • Analytics
The Principal AI/ML Engineer will develop machine learning models for campaign optimization in AdTech, collaborating across engineering and product teams to enhance advertising capabilities.
Top Skills: SparkAWSCassandraDockerDynamoDBGoHadoopJavaKafkaKubernetesMySQLPostgresPythonPyTorchRedisTensorFlow
Reposted 18 Days AgoSaved
Easy Apply
Hybrid
Boston, MA
Easy Apply
244K-366K Annually
Expert/Leader
244K-366K Annually
Expert/Leader
Consumer Web • eCommerce • Marketing Tech • Retail • Software • Analytics • Generative AI
The Principal Engineer will lead enterprise scalability efforts, driving architectural changes, optimizing systems, and integrating AI for improved operational performance across multi-tenant SaaS platforms.
Top Skills: AIBack-PressureCachingCapacity PlanningMulti-Region ReadinessPartitioningPerformance EngineeringSharding
Reposted 13 Days AgoSaved
In-Office
Boston, MA
75K-232K Annually
Senior level
75K-232K Annually
Senior level
Hardware • Semiconductor
The Principal Engineer - Process will support manufacturing and development of the Chip Scale Atomic Clock, focusing on process optimization, materials analysis, and lean manufacturing methodologies.
Top Skills: BomsErpLean ManufacturingPlmSix SigmaStatistical Methods
Reposted 9 Days AgoSaved
Easy Apply
Remote or Hybrid
Boston, MA
Easy Apply
225K-250K Annually
Senior level
225K-250K Annually
Senior level
Artificial Intelligence • Machine Learning
Design and build scalable backend platforms for regulated scientific workflows, ensuring compliance and reproducibility while enhancing performance and usability across cloud environments.
Top Skills: AWSAzureDockerGCPGoGrpcJavaKubernetesPythonRestScala
Reposted 4 Days AgoSaved
Remote
Boston, MA
128K-261K Annually
Senior level
128K-261K Annually
Senior level
Cloud • Security • Software • Cybersecurity
The Principal Engineer will design, implement, and deploy tools and workflows to enhance engineering productivity, working closely with teams to improve software delivery.
Top Skills: AWSBazelGithub ActionsGoJfrog ArtifactoryLaunchdarklyPythonSonarqubeSpinnakerTerraform
Reposted 10 Days AgoSaved
Easy Apply
Remote or Hybrid
Boston, MA
Easy Apply
152K-190K Annually
Expert/Leader
152K-190K Annually
Expert/Leader
Cloud • Healthtech • Professional Services • Software • Pharmaceutical
This role involves designing and developing core modules for an enterprise-level clinical data platform, ensuring compliance with quality standards, and collaborating with teams for software development and testing.
Top Skills: AngularAsp.Net MvcAWSC#CSSHTMLJavaScriptSQLTypescript
6 Days AgoSaved
Remote
Boston, MA
105K-115K Annually
Senior level
105K-115K Annually
Senior level
Healthtech • Pharmaceutical
Lead systems engineering for infusion medical devices: develop and manage system/subsystem requirements, ensure regulatory compliance (DHF, ISO, IEC, FDA), support risk management, V&V, and cross-functional design activities, investigate root causes, and document system assessments throughout the product lifecycle.
Top Skills: Iso 13485,Iso 14971,Iec 62304,Fda Regulations,Design History File (Dhf),Risk Management,Verification And Validation (V&V)
Reposted 20 Days AgoSaved
In-Office
Boston, MA
227K-284K Annually
Expert/Leader
227K-284K Annually
Expert/Leader
Artificial Intelligence • Cloud • Software • Infrastructure as a Service (IaaS)
Lead the technical direction of PaaS at DigitalOcean by architecting and implementing robust cloud-native services while mentoring engineers and ensuring system reliability.
Top Skills: C++GoJavaPython
Reposted 15 Days AgoSaved
Remote or Hybrid
Boston, MA
211K-284K Annually
Senior level
211K-284K Annually
Senior level
Artificial Intelligence • Automotive • Machine Learning • Transportation
As a Principal Engineer on the Behaviors team, you will guide the technology direction, lead complex initiatives, and mentor engineers to enhance autonomous vehicle capabilities through ML solutions.
Top Skills: C++CudaDeep LearningMachine LearningPythonPyTorch
Reposted 15 Days AgoSaved
In-Office
Boston, MA
275K-412K Annually
Expert/Leader
275K-412K Annually
Expert/Leader
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
The Principal State Estimation Engineer will develop advanced sensor fusion algorithms for UAV navigation, integrating multiple sensor data and ensuring robust performance in contested environments.
Top Skills: C++11CudaLinux
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