Top Principal Engineer Jobs in Boston, MA

Build and operate Legion’s secure, scalable AWS and Kubernetes platform. Responsibilities include infrastructure automation, CI/CD, monitoring, alerting, incident response, operational runbooks, production support, and on-call participation. The role also develops production AI agents for SRE automation and owns a secure platform for engineering teams to build and operate agents with sandboxing, scoped credentials, integrations, cost controls, observability, and reliability guardrails.

Lead the architecture, development, testing, and deployment of hyperscale distributed storage systems optimized for AI and machine learning workloads. Drive innovations in scalability, performance, security, durability, and efficiency while collaborating with AI researchers and cloud infrastructure teams. Mentor engineers, guide technical strategy, and help shape Azure Blob Storage into an AI-native platform supporting zettabyte-scale storage.

Design, build, test, and support EPIC integration solutions across the full interface lifecycle. Gather requirements, resolve integration issues, develop standards and documentation, and provide production support within a remote, volunteer, part-time setup.

Owns the implementation, hardening, and polish of AI behaviors and systems for a narrative-driven AAA game. Collaborates with design and animation teams to create believable enemy behaviors, ensure critical AI systems are stable and reliable, and deliver a shipping-ready player experience. Requires extensive Unreal Engine experience, strong C++ skills, modern game AI architecture knowledge, animation expertise, and at least one shipped game focused on AI.

Develops novel sensor technologies and detection methods for next-generation diagnostic and point-of-care medical devices. Responsibilities include planning and conducting laboratory experiments, applying scientific methods, analyzing data, documenting results, collaborating with multidisciplinary teams, and guiding junior personnel. The role requires expertise in sensor technology, electrochemistry, engineering, chemistry, microfluidics, lab-on-a-chip systems, and biomedical applications, with occasional domestic and international travel.

Design and lead development of high-performance networking infrastructure for large-scale AI training and inference in Azure. Architect low-latency, low-jitter communication frameworks, optimize distributed systems, benchmark scalability, resolve complex networking issues, and improve reliability, observability, and performance. Mentor engineers, create technical designs, manage dependencies, and participate in on-call operations for critical services.

Develops and maintains high-quality systems software and microservices for Azure Messaging services, including data storage and replication. Drives product and engineering-process innovation, applies AI to software development, ensures software quality and stability, and uses rigorous development practices including requirements, testing, and efficient coding techniques.

Owns the design, administration, security, modernization, and recovery of Liquidia’s hybrid IT infrastructure across Azure, servers, virtualization, storage, and enterprise networks. Provides hands-on engineering, roadmap development, disaster recovery, patching, automation, vendor direction, documentation, and onsite support for manufacturing and laboratory systems. Ensures infrastructure complies with SOX, GxP, and 21 CFR Part 11 requirements while coordinating qualification, validation, change control, and infrastructure improvement initiatives.

Leads architecture and development of Azure Storage table, metadata, and indexing systems at massive cloud scale. Designs distributed-system primitives for partitioning, indexing, transactions, consistency, replication, caching, and high-performance data access. Drives architectural decisions, prototypes innovations through production, and improves performance, scalability, reliability, and cost efficiency. Requires deep expertise in distributed storage, databases, or large-scale systems.

Leads the design and development of scalable SaaS applications, including AI-powered features such as semantic search, vector databases, RAG, and LLM orchestration. Provides technical leadership, mentorship, architectural guidance, code reviews, and engineering standards enforcement. Collaborates cross-functionally to translate requirements into robust solutions, champions AI-assisted development tools, builds developer experience tooling, and drives innovation, quality, security, and continuous improvement across the engineering organization.

Define architectural direction for Azure Specialized platform services and lead the design of highly available distributed cloud systems. Drive reliability, scalability, observability, security, diagnostics, and operational improvements across engineering organizations. Establish service health frameworks, SLOs, metrics, and governance for mission-critical services. Mentor engineers, influence technical strategy, resolve complex cross-system challenges, and advance AI-assisted troubleshooting and platform modernization.

Lead design and prototyping of generative AI experiences for autonomy development; drive UX for Hivemind products; perform user research, collaborate with CTO and product leads, and deliver reference implementations and integrations across full-stack web and edge systems.

Leads automation engineering for a regulated medical-device manufacturing site. Responsibilities include developing automation roadmaps, supporting and troubleshooting automated equipment, leading machine vision and robotics initiatives, qualifying and validating equipment, implementing corrective actions, improving reliability, and deploying emerging technologies. Partners with cross-functional and regional teams to execute automation projects and ensure compliance with quality, safety, validation, and regulatory requirements. The role is onsite in Danvers, Massachusetts, with 10–15% travel.

As a Principal Engineer for Core Infrastructure at Klaviyo, you will architect and enhance the Kubernetes platform and CI/CD pipelines, improve developer velocity, and ensure operational excellence while incorporating AI tools for automation and incident response.

Leads end-to-end electrical design for robotic material-handling systems, including architecture, schematics, PCB layout, harnesses, power distribution, integration, testing, EMC/EMI validation, and production release. Owns designs through manufacturing ramp, collaborates with contract manufacturers and cross-functional teams, investigates field failures, supports customer and test-site bring-up, and mentors electrical designers while driving process and technical quality.

Architects and standardizes laboratory automation deployments, including robotic systems, orchestration software, LIMS, ELN, and third-party integrations. Defines commissioning standards, acceptance criteria, integration patterns, and testing methods; leads new product introduction and resolves complex technical escalations. The role mentors engineers, develops training and documentation, partners cross-functionally, and selectively supports high-risk customer deployments. Requires extensive laboratory automation experience, object-oriented programming, robotic arm integration, and travel up to 20%.

Provides principal-level engineering support for Air Force network and communications systems. Responsibilities include planning, designing, integrating, testing, operating, and maintaining wired, wireless, and Private 5G infrastructure. The role supports RF, 5G Core, gNodeB, network architecture, switching, routing, NAC interoperability, capacity and performance monitoring, backup and recovery, operating system maintenance, and cybersecurity policy implementation in a DoD environment.

Leads the design, integration, implementation, commissioning, and lifecycle improvement of enterprise OT, telemetry, and SCADA solutions across global data centers. Translates operational and customer requirements into secure, scalable architectures; integrates field devices, BMS/EPMS, Ignition, Azure services, messaging, APIs, and data platforms; troubleshoots multidisciplinary issues; leads testing and modernization; and mentors engineers and stakeholders.

Principal Frontend Engineer responsible for defining and governing large-scale frontend architecture across clinical applications. Leads modernization from fragmented systems to a React-based platform using JavaScript, TypeScript, Node.js, GraphQL, and shared component standards. Drives migration strategy, technical governance, performance improvements, AI-assisted development tooling, and cross-team alignment while mentoring engineers. Advises on CI/CD, AWS infrastructure, Oracle integrations, legacy Perl utilities, security, hiring, and long-term workforce planning.

Leads the roadmap, architecture, security, and organizational adoption of CI/CD and release infrastructure. Designs scalable release gates, hardens supply chains, directs engineers through complex projects, manages severe incidents, and drives cross-functional technical alignment. The role remains hands-on through code reviews, prototyping, debugging, documentation, mentorship, and design reviews while primarily achieving impact through team leadership.

Design, build, and operate distributed storage and file-system platforms for cloud-scale AI training and inference. Architect storage and caching for Kubernetes and GPU workloads, improve performance, reliability, observability, and resiliency, diagnose cross-layer production issues, and lead architecture reviews. Partner across infrastructure, networking, operating systems, and AI platform teams while mentoring engineers and shaping long-term storage strategy.

Lead the architecture, technical strategy, and roadmap for Microsoft's Windows ML compiler stack. Design high-performance compiler infrastructure, execution engines, optimization frameworks, and developer tools supporting CPU, GPU, and NPU workloads. Drive NPU enablement, graph optimization, scheduling, memory management, code generation, and hardware abstraction. Partner with silicon vendors and internal teams, influence AI hardware and platform strategy, lead cross-team initiatives, and mentor engineers developing on-device and generative AI capabilities.

Design, develop, customize, and administer ServiceNow ITSM applications. Build scripts, workflows, interfaces, reports, and dashboards; integrate ServiceNow with external systems using REST and SOAP. Provide troubleshooting and end-user support, analyze requirements, improve processes, and support testing and deployments. Serve as a senior technical authority by leading customer engagements, technical documentation, demonstrations, innovation initiatives, stakeholder collaboration, and mentoring junior staff.

Designs, develops, and optimizes embedded firmware for microcontroller-based motion control systems. Responsibilities include bare-metal and RTOS development, motor and sensor interfaces, low-level drivers, hardware bring-up, board-level debugging, peripheral integration, performance optimization, documentation, design reviews, and mentoring junior engineers.

Leads electrical engineering projects from concept through production, designing PWM amplifiers, power converters, power supplies, and embedded hardware/software. Develops microprocessor and FPGA solutions, performs circuit simulation and validation, oversees PCB design, and tests prototypes using laboratory equipment. Ensures manufacturability, reliability, and performance while collaborating with cross-functional engineering teams.