Top Principal Engineer Jobs in Boston, MA

Leads FPGA architecture, HDL development, verification, integration, and release activities for medical diagnostic products. Collaborates with hardware and software engineering teams on interfaces, system-level debugging, design quality, and product releases. Performs complex design trade-off analysis, defect investigation, documentation, and technical mentoring. Supports schedules, CAPA or complaint investigations, and cross-functional technical communication.

Lead architecture, design, and delivery of PET product features; write production full‑stack code; champion testing, observability, CI/CD and operational readiness; mentor engineers and collaborate with product to shape technical roadmap.

Design and develop massively parallel distributed database kernels for real-time analytics at terabyte and petabyte scale. Responsibilities include low-level C++ development, MPP query execution, SIMD and hardware optimization, distributed communication using MPI and RDMA technologies, database internals, vector indexing, in-database machine learning, performance tuning, architecture reviews, mentoring, and resolving scalability issues.

Lead high-leverage technical work across teams: define architecture and patterns, drive end-to-end delivery and operational excellence, ship AI-enabled systems, mentor engineers, set AI guardrails, and represent technical leadership internally and externally.

Lead the design and development of Microsoft’s global-scale, Kubernetes-based cloud service platform. Provide technical leadership across teams, define requirements and architecture, mentor engineers, oversee project and release plans, and serve as a responsible on-call owner. Improve platform availability, reliability, security, observability, efficiency, and performance while standardizing service delivery across Microsoft cloud workloads.

Leads high-speed data converter development, selecting circuit architectures and designing transistor-level CMOS circuits. Prepares design documentation, conducts reviews, guides layout, evaluation, and test teams, and mentors engineers. The role requires advanced electrical engineering education, extensive CMOS design experience, expertise in ADC and DAC architectures, analog circuit design, Cadence and SPICE tools, and MATLAB-based behavioral modeling. Strong communication and teamwork skills are also needed.

Provides principal-level systems engineering support across the Department of the Air Force acquisition lifecycle. Responsibilities include requirements analysis, enterprise and system-of-systems architecture, mission integration, interoperability, risk mitigation, test and evaluation planning, and technical documentation. The role focuses on developing and assessing ICAM solutions, addressing capability gaps, coordinating with DoD and coalition stakeholders, and supporting acquisition strategies for the DAF Battle Network. This is a full-time, 100% onsite position at Hanscom AFB.

Lead research, architecture, and production development of hardware formal verification tools enhanced by agentic AI. Build formal verification algorithms, multi-agent systems, solver orchestration, RTL analysis, automated SystemVerilog Assertion generation, and high-performance C/C++ implementations for commercial EDA suites. The role requires deep expertise in formal methods, hardware verification, AI frameworks, RTL languages, and 15+ years developing advanced EDA tools.

Leads supplier transfer and optimization projects for medical device manufacturing. Manages cross-functional teams, project schedules, budgets, risks, KPIs, and supplier qualification activities. Applies Lean Six Sigma and structured problem-solving to improve process capability, quality, lead times, cost, and supply chain resilience. Reviews supplier designs, supports phase-in/phase-out planning, and ensures successful site-to-site transfers while coordinating with engineering, operations, quality, sourcing, and category management teams.

Lead the strategy, architecture, and scaling of CI/CD and DevOps platforms across multiple product teams. Design secure, resilient pipelines; implement infrastructure as code and cloud environments; integrate security, monitoring, logging, and alerting; improve developer productivity and self-service workflows; optimize build performance; and mentor engineering teams while driving standards and adoption of modern DevOps and AI practices.

The Principal SDET will lead automation framework development, mentor teams, drive migration to modern testing solutions, and collaborate across engineering teams to enhance quality and efficiency.

Designs and develops scalable full-stack software applications and platform features in a cloud-native enterprise environment. Leads application architecture, complex projects, testing, documentation, CI/CD implementation, risk management, and technical solution development. Collaborates with business and engineering teams, advises senior management, coordinates project delivery, and mentors junior engineers. Uses Angular and TypeScript for front-end systems and Java, Spring Boot, REST, databases, Docker, Jenkins, and Kubernetes for secure distributed backend and deployment solutions.

Architects, develops, and governs enterprise Archer GRC solutions, including workflows, custom objects, integrations, dashboards, reporting, and data models. Partners with risk, compliance, audit, legal, and business stakeholders to deliver scalable solutions. Leads application architecture, testing, documentation, project planning, technical strategy, and modernization efforts. Requires advanced Archer configuration and integration expertise using APIs, JavaScript, Python, SQL, and third-party platforms. Mentors engineers and advises senior management.

Lead the architecture and operation of Yahoo’s enterprise developer experience platform, including CI/CD, artifact management, GitOps deployments, and developer tooling. Design production agentic AI automation with evaluation frameworks, correctness checks, and security guardrails. Establish standardized workflows, templates, and CI practices; improve developer productivity through AI-assisted engineering and self-service portals. Partner with security and compliance teams, provide technical leadership, guide architecture reviews, mentor engineers, and measure platform adoption and reliability.

The Principal Engineer will shape the technical strategy for messaging infrastructure, influence architectural decisions across teams, and solve complex technical problems. Responsibilities include mentoring engineers, driving coherence across teams, and leading initiatives to ensure Weave's competitiveness in messaging solutions.

Lead the technical direction for integrating algorithms on the Prism Mapping platform, focusing on real-time signal pipelines and optimization strategies. Collaborate with teams to ensure robust clinical performance and timely delivery of new capabilities.

Lead the technical direction and architecture for the core infrastructure of the Prism Mapping platform, ensuring reliability and performance in a medical device environment. Mentor engineers and drive technical improvements while communicating complex decisions to stakeholders.

Lead architectural design for real-time 3D visualization on the Prism Mapping platform, mentor engineers, and define the long-term visualization roadmap.

Lead the UI architecture for the Prism Mapping application, drive design and delivery of major subsystems, mentor engineers, and shape technical direction in a clinical environment.

Lead the architecture and evolution of managed Kubernetes and cloud-native services. Provide cross-team technical oversight, standardize platform practices, integrate open-source technologies, improve scale, performance, security, and operational efficiency, and mentor engineering teams. The role requires expertise in Kubernetes-based platforms, container runtimes, cloud-native architectures, and Go, Python, or Bash.

Lead design, build, deployment, and operation of highly resilient, high-throughput configuration and publishing systems. Define long-term architecture and strategy, mentor senior engineers, diagnose and fix performance bottlenecks, and leverage AI tools to improve engineering productivity and platform capabilities.

Develop and deploy software for laboratory automation systems, including instruments, liquid handlers, robotic workcells, and data workflows. Integrate APIs, databases, LIMS, ELN, and enterprise systems while troubleshooting hardware and software issues. Collaborate with scientists, engineers, and vendors to optimize laboratory processes, improve data quality, and support drug development. Create documentation, user guides, and software validation records.

No specific responsibilities listed. Senior technical leadership role to develop and direct hedge fund and analytics technology platforms, collaborate with investment stakeholders, design and implement analytics systems, and mentor engineering staff.

Build, operate, and secure cloud-native and edge infrastructure including Kubernetes, artifact pipelines, application streaming, and air-gapped appliances. Partner with product, GRC, and mission owners to design, deploy, and harden systems, remediate vulnerabilities, support audits (IL5/IL6/JWICS), and ensure trusted artifact delivery across environments.

Lead the design and evolution of cloud-native platforms, distributed systems, and infrastructure services at large scale. Define architecture across compute, networking, storage, datacenter, and AI infrastructure environments. Improve automation, lifecycle management, observability, reliability, security, and developer productivity. Guide technical strategy across engineering organizations while contributing to GPU, HPC, bare-metal, networking, and distributed computing platforms. Mentor engineers and foster technical excellence through architecture reviews and cross-organizational collaboration.