Top Principal Engineer Jobs in Boston, MA

Reposted 8 Days AgoSaved
Easy Apply
Hybrid
Boston, MA
Easy Apply
152K-190K Annually
Expert/Leader
152K-190K Annually
Expert/Leader
Cloud • Healthtech • Professional Services • Software • Pharmaceutical
This role involves designing and developing core modules for an enterprise-level clinical data platform, ensuring compliance with quality standards, and collaborating with teams for software development and testing.
Top Skills: AngularAsp.Net MvcAWSC#CSSHTMLJavaScriptSQLTypescript
Reposted 4 Days AgoSaved
In-Office
Boston, MA
144K-288K Annually
Expert/Leader
144K-288K Annually
Expert/Leader
Fitness • Healthtech • Retail • Pharmaceutical
The Principal Engineer for Conversational AI will lead engineering teams, design software solutions, and ensure high-quality products in voice and chat bots, while collaborating across functions.
Top Skills: APIsC#JavaJavaScriptLlmsMicroservicesNlpNluPythonSQLSttTts
Reposted 4 Days AgoSaved
In-Office
Boston, MA
144K-288K Annually
Expert/Leader
144K-288K Annually
Expert/Leader
Fitness • Healthtech • Retail • Pharmaceutical
The Principal Engineer for Conversational AI will lead engineering teams, develop high-quality AI software solutions, and ensure operational excellence. They will oversee design and code reviews, mentor team members, and drive technical vision in cloud environments.
Top Skills: APIsC#JavaJavaScriptLlmsMicroservicesNlu/NlpPythonSQLStt/Tts
Reposted 10 Days AgoSaved
Hybrid
Boston, MA
168K-231K Annually
Senior level
168K-231K Annually
Senior level
Automotive • eCommerce • Hardware • Music • Retail • Software • Wearables
Lead system architecture and engineering for advanced audio products, collaborating across teams to define technical strategies and ensure successful product development.
Top Skills: Ai/MlCloud EngineeringData AnalysisDspEmbedded SystemsSystems Engineering
Reposted 4 Days AgoSaved
Hybrid
Boston, MA
170K-220K Annually
Expert/Leader
170K-220K Annually
Expert/Leader
Artificial Intelligence • Healthtech
The Integration and Test Architect will lead the design of system integration and test processes for robotic platforms, ensuring comprehensive testing and collaboration across multiple engineering disciplines to pave the way for successful product launches.
Top Skills: CadLabviewMatlabSimulinkSolidworks
Reposted 4 Days AgoSaved
In-Office
Boston, MA
122K-177K Annually
Senior level
122K-177K Annually
Senior level
Biotech
The role involves developing applications and tools for data visualization in clinical trials, managing projects, and ensuring compliance with data standards. Responsibilities include programming in R, creating dashboards, and integrating data across clinical systems.
Top Skills: Azure DevopsData.TableDplyrGgplot2GitKnitrLeafletPlotlyPurrrRRcolorbrewerStringrTidyr
Reposted 10 Days AgoSaved
Hybrid
Boston, MA
172K-216K Annually
Senior level
172K-216K Annually
Senior level
Consumer Web • eCommerce • Software
The Principal AI Engineer will design AI-powered workflows, partner with stakeholders, and build production-level systems in a cross-functional environment.
Top Skills: Ai ApisAWSPythonSalesforce Apis
Reposted 10 Days AgoSaved
Easy Apply
In-Office
Boston, MA
Easy Apply
206K-284K Annually
Expert/Leader
206K-284K Annually
Expert/Leader
Machine Learning • Security • Software • Analytics • Defense
The role involves developing advanced signal processing algorithms, leading projects, engaging with customers, and supporting business development initiatives. Requires deep technical knowledge and leadership in radar and electronic warfare solutions.
Top Skills: Ai/Ml AlgorithmsC/C++MatlabPython
Reposted 10 Days AgoSaved
Hybrid
Boston, MA
128K-225K Annually
Senior level
128K-225K Annually
Senior level
Artificial Intelligence • Fintech • Insurance • Marketing Tech • Software • Analytics
The Principal Front-Office Engineer will lead the design and implementation of AI-driven solutions in investment strategies, collaborating with analysts to enhance toolsets and reporting systems.
Top Skills: CvxpyDashGitNumpyPandasPlotlyPythonScikit-LearnScipySQL
Reposted 10 Days AgoSaved
Easy Apply
Hybrid
Boston, MA
Easy Apply
220K-250K Annually
Expert/Leader
220K-250K Annually
Expert/Leader
Artificial Intelligence • Information Technology • Professional Services • Social Impact • Software
The Principal Front-End Engineer will enhance the Growth team's platform and infrastructure by developing tools, managing applications, and ensuring a high-quality user experience across projects.
Top Skills: AWSClaude CodeCloudflareGithub ActionsKubernetesNext.JsReactRemixSanity CmsTanstack StartTerraform
Reposted 24 Days AgoSaved
Easy Apply
In-Office or Remote
Boston, MA
Easy Apply
260K-300K Annually
Expert/Leader
260K-300K Annually
Expert/Leader
Artificial Intelligence • Hardware • Healthtech • Software
The Principal Engineer will lead the engineering team in building systems across full stack, improving development efficiency, and expanding products in new markets.
Top Skills: AWSBackend ServicesComputer VisionDatabricksEmbedded SystemsIotKafkaMlMobileNode.jsTypescriptUnity Catalog
Reposted 6 Days AgoSaved
In-Office
Boston, MA
159K-286K Annually
Expert/Leader
159K-286K Annually
Expert/Leader
Healthtech • Biotech
Design, implement, and standardize robotics control solutions (PLC/HMI/SCADA/motion) for GMP manufacturing, lead FAT/SAT/commissioning, support validation and integration with IIoT/digital systems, manage vendors and projects, mentor staff, and ensure compliance with GxP/GAMP and data integrity. Travel up to 25% to support global project execution.
Top Skills: Application ServersHistoriansHmiIiotIndustrial NetworksMotion ControlPlcProcess Control SystemsRockwellScadaSiemens
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Reposted 6 Days AgoSaved
In-Office
Boston, MA
75K-232K Annually
Senior level
75K-232K Annually
Senior level
Hardware • Semiconductor
The Principal Engineer - Process will support manufacturing and development of the Chip Scale Atomic Clock, focusing on process optimization, materials analysis, and lean manufacturing methodologies.
Top Skills: BomsErpLean ManufacturingPlmSix SigmaStatistical Methods
Reposted 6 Days AgoSaved
In-Office
Boston, MA
75K-232K Annually
Senior level
75K-232K Annually
Senior level
Hardware • Semiconductor
The Principal Engineer will lead electronic systems development for atomic clocks, mentor engineers, and collaborate across teams on design execution.
Top Skills: AgileAnalog CircuitsCad ToolsDigital CircuitsEmbedded MicrocontrollersFpgaMixed Signal CircuitsRf DesignVerilogVhdl
2 Days AgoSaved
In-Office or Remote
Boston, MA
140K-160K Annually
Senior level
140K-160K Annually
Senior level
Big Data • Information Technology • Software • Analytics • Energy
Lead design and build of scalable backend systems and data platforms; own architecture and production deployments; improve reliability, performance, and observability; mentor engineers and collaborate with Product, Data Science, SRE, and Security.
Top Skills: ArgoAWSAws BedrockClaudeClickhouseDockerGoGrafanaHoneycombKafkaKubernetesLangchainMySQLPulumiPythonRustSentryTerraform
6 Days AgoSaved
In-Office
Boston, MA
192K-240K Annually
Expert/Leader
192K-240K Annually
Expert/Leader
Fintech • Insurance • Financial Services
Lead design, development, and deployment of production-grade AI systems (LLM apps, retrieval pipelines). Own technical direction, ensure scalability, reliability, security, and responsible AI. Drive MLOps, model evaluation, monitoring, and mentor engineers while partnering with product and business stakeholders.
Top Skills: Ai/Ml FrameworksData PipelinesLlmMlopsModel Lifecycle ManagementPythonRetrieval PipelinesRustTypescript
Reposted 12 Days AgoSaved
Hybrid
Boston, MA
106K-177K Annually
Senior level
106K-177K Annually
Senior level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
The Principal Packaging Engineer will oversee lab operations, manage packaging development projects, ensure compliance with standards, and provide strategic direction to teams.
Top Skills: Fda RegulationsGmpIso 13485
Reposted 12 Days AgoSaved
Easy Apply
Hybrid
Boston, MA
Easy Apply
152K-190K Annually
Senior level
152K-190K Annually
Senior level
Cloud • Healthtech • Professional Services • Software • Pharmaceutical
The Principal SDET will lead automation framework development, mentor teams, drive migration to modern testing solutions, and collaborate across engineering teams to enhance quality and efficiency.
Top Skills: .NetAWSC#DockerHttp/HttpsPlaywrightRest ApisSQL
Reposted 12 Days AgoSaved
Easy Apply
In-Office
Boston, MA
Easy Apply
204K-284K Annually
Expert/Leader
204K-284K Annually
Expert/Leader
Machine Learning • Security • Software • Analytics • Defense
The position involves reversing complex software/firmware, developing cybersecurity solutions, leading technical teams, and conducting vulnerability research, all while ensuring national security.
Top Skills: Afl++ArmBinary NinjaC/C++GhidraIda ProPythonQemuX86
13 Days AgoSaved
Easy Apply
In-Office
Boston, MA
Easy Apply
144K-205K Annually
Senior level
144K-205K Annually
Senior level
Artificial Intelligence • Big Data • Healthtech • Machine Learning • Software • Database • Analytics
Design, implement, and maintain DevSecOps features for cloud-native and on-prem database platforms. Collaborate with product and cross-functional teams, follow development workflows (source control, code reviews, CI/CD), write automated tests, and support security, configuration, monitoring, licensing, and upgrades across Kubernetes and traditional deployments.
Top Skills: AixAWSBashC/C++Claude CodeDockerGitlabGoHelmIntersystems IrisJavaKubernetesOauth 2.0/OidcObjectscriptOpentelemetry (Otel)PerforcePythonRhelSuse Linux EnterpriseUbuntuVs CodeWindowsYaml
3 Days AgoSaved
Remote or Hybrid
Boston, MA
Expert/Leader
Expert/Leader
Fintech • Software
Lead frontend architecture and implementation for a high-performance SPA and Node.js BFF. Solve algorithmic, concurrency, and memory challenges, optimize performance and builds, drive observability, security, and CI/CD, mentor engineers, and collaborate with product, UX, and SRE teams to deliver resilient, distributed real-time collaborative features.
Top Skills: AksAngularBrowser ApisC# .NetCanvasDockerEcmascriptFrontend Test FrameworksGraphQLGrpcHTTPIacJava Spring BootJavaScriptKubernetesLong PollingMicro-FrontendsNode.jsPostgresReactReduxRedux-SagaRestSignalrSQL ServerTypescriptV8 EngineWeb WorkersWebsockets
13 Days AgoSaved
Easy Apply
Hybrid
Boston, MA
Easy Apply
152K-283K Annually
Expert/Leader
152K-283K Annually
Expert/Leader
Artificial Intelligence • Cloud • Insurance • Software • Database • Conversational AI • Generative AI
Build internal AI operations infrastructure and tools (knowledge systems, agent-builder UIs, dashboards, catalogs). Design data flows and decide centralization vs decentralization. Create discoverable, governable surfaces for teams to compose and trust agents. Run a portfolio of small internal products, prioritize requests, and ship production code while partnering with a technical infrastructure counterpart.
Top Skills: Aws BedrockAws CdkAws CognitoClaude CodeCodexCursorNext.JsReactShadcn/UiTailwindTypescript
13 Days AgoSaved
Easy Apply
Hybrid
Boston, MA
Easy Apply
152K-283K Annually
Expert/Leader
152K-283K Annually
Expert/Leader
Artificial Intelligence • Cloud • Insurance • Software • Database • Conversational AI • Generative AI
Lead design and build of an AWS-only AI Operations platform: hosting, IaC, registries (Accountability, Agent, Tool), identity/authorization patterns, developer DX, observability, and security hooks for agentic systems. Evangelize internally and partner on compliance and security integrations.
Top Skills: AgentcoreAws BedrockAws CognitoAws IamAws LambdaCdkClaude CodeCursorDlpDynamoDBEventbridgeGoModel Context Protocol (Mcp)Oauth 2.1PostgresPythonSagemakerTerraformTypescriptWorkshop Studio
4 Days AgoSaved
Easy Apply
Remote
Boston, MA
Easy Apply
195K-270K Annually
Senior level
195K-270K Annually
Senior level
Artificial Intelligence • Fintech • Machine Learning • Social Impact • Software
Lead Android migration and launch across Cash Line and Unsecured Installment products. Define mobile architecture, partner with product/design, mentor engineers, deliver high-quality native Android and React Native solutions, and continue as a mobile specialist post-launch to improve performance and scalability.
Top Skills: AndroidJavaKotlinReact NativeTypescript
Reposted 4 Days AgoSaved
Easy Apply
Remote or Hybrid
Boston, MA
Easy Apply
300K-400K Annually
Expert/Leader
300K-400K Annually
Expert/Leader
AdTech • Artificial Intelligence • Marketing Tech • Software • Analytics
The Principal AI/ML Engineer will develop machine learning models for campaign optimization in AdTech, collaborating across engineering and product teams to enhance advertising capabilities.
Top Skills: SparkAWSCassandraDockerDynamoDBGoHadoopJavaKafkaKubernetesMySQLPostgresPythonPyTorchRedisTensorFlow
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