Top Principal Engineer Jobs in Boston, MA

As a Principal Software Engineer, you will design, develop, and implement complex software solutions, lead projects, and ensure compliance with standards in a cloud-first environment.

This role involves designing and developing core modules for an enterprise-level clinical data platform, ensuring compliance with quality standards, and collaborating with teams for software development and testing.

Lead design and implementation of RF hardware systems, collaborating with teams on system requirements and hardware designs, while supporting assembly, integration, and testing.

Lead engineering strategy and implementation for cGMP bioprocess and bioconjugation manufacturing. Design, optimize, and scale processes and equipment, develop PAT and automation control strategies, oversee CDMO activities, ensure regulatory compliance, and drive continuous improvement across cross-functional teams.

The Principal Security Engineer leads projects, drives technical vision, mentors engineers, engages in business development, and oversees security software development.

The role involves designing, developing, and deploying efficient code, managing client communications, and providing technical guidance while ensuring quality control in clinical data services.

Lead technical teams in developing real-time software for RF sensor systems, transitioning algorithms from prototypes to production, and mentoring junior engineers.

As a Principal Software Engineer, you will architect and develop virtualization technology for vehicle testing, mentor teams, and enhance code quality across GM products.

The Principal Software Engineer will tackle platform-level challenges, assist team members, write secure and scalable code, and develop features for cloud storage solutions.

Design, build, train, and deploy AI models for healthcare applications, collaborate with product management, and integrate solutions.

The Principal Software Engineer will set technical direction, own cross-team initiatives, evolve platform architecture, and lead experimentation efforts while mentoring others in the Personal Loans team.

The Principal Engineer - Process will support manufacturing and development of the Chip Scale Atomic Clock, focusing on process optimization, materials analysis, and lean manufacturing methodologies.

As a Principal Software Engineer, you'll modernize DevX Pipelines, enhance CI/CD infrastructure, and promote software delivery efficiency.

The Principal Engineer will lead enterprise scalability efforts, driving architectural changes, optimizing systems, and integrating AI for improved operational performance across multi-tenant SaaS platforms.

The position involves reversing complex software/firmware, developing cybersecurity solutions, leading technical teams, and conducting vulnerability research, all while ensuring national security.

The Principal Engineer will lead the Test Platform Services team, focusing on building validation systems, ensuring reliability and scalability, and fostering team growth.

The Principal Specialist Sales Engineer will drive sales engineering efforts, focusing on cybersecurity solutions within vulnerability management and SecOps, while collaborating with customers and partners to secure digital transformations.

Lead technical vision and execution for enterprise-scale AI, automation, and data initiatives. Architect scalable, secure AI systems and data pipelines, mentor engineers, drive cross-functional alignment, and deliver high-impact production solutions that improve productivity and business outcomes.

Lead the architectural design and development of a new consumer credit product, focusing on backend systems, distributed services, and integrating AI tools. Mentor team members and influence product direction through engineering insights.

Lead a team in developing full-stack SaaS solutions, driving architecture, mentoring engineers, and collaborating with product management to enhance the web app and tech stack.

Lead the technical direction of PaaS at DigitalOcean by architecting and implementing robust cloud-native services while mentoring engineers and ensuring system reliability.

The Principal Radar Systems Engineer leads radar system development, collaborates with multi-disciplinary teams, and ensures effective solutions to customer needs while applying systems engineering principles.

The Principal Engineer, Hardware will design and develop hardware architectures, collaborate with engineering teams, and mentor junior staff while ensuring project goals are met.

The Principal Software Engineer will lead AI automation efforts at Coinbase, designing AI-driven systems, mentoring teams, and solving complex AI challenges to improve operations and developer productivity.

The Principal ML Engineer at Agero will develop and productionize a Dispatch System using ML models, optimize decision-making processes, and lead a team to improve operational performance.