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Top Principal Engineer Jobs in Boston, MA

Reposted 2 Days AgoSaved
Remote or Hybrid
Boston, MA
240K-330K Annually
Expert/Leader
240K-330K Annually
Expert/Leader
Artificial Intelligence • Automotive • Machine Learning • Transportation
Lead R&D of motion planning, trajectory generation, and control algorithms and ML models for autonomous vehicles. Architect systems with cross-functional teams, design simulation and validation for edge cases, document findings for safety traceability, and mentor junior engineers.
Top Skills: C++DdsLinuxPythonRosRust
Reposted 3 Days AgoSaved
In-Office
Boston, MA
148K-222K Annually
Senior level
148K-222K Annually
Senior level
Biotech • Pharmaceutical
Lead the development of automated solutions for data QC and reporting in biotechnology, ensuring accuracy and standardization of regulatory documents.
Top Skills: AICloud-Native PlatformsMlPythonR
3 Days AgoSaved
In-Office
Boston, MA
138K-180K Annually
Expert/Leader
138K-180K Annually
Expert/Leader
eCommerce • Fashion • Retail
Lead the technical strategy and architecture of Oracle platforms, ensuring high performance, compliance, and optimal operations while mentoring teams and overseeing design and governance.
Top Skills: AutomationExadataExadata Cloud@CustomerGoldengateInfrastructure-As-CodeMonitoring ToolsOracleOracle Cloud InfrastructureOracle Key VaultWeblogicZfs
8 Days AgoSaved
Easy Apply
In-Office
Boston, MA
Easy Apply
206K-284K Annually
Expert/Leader
206K-284K Annually
Expert/Leader
Machine Learning • Security • Software • Analytics • Defense
Lead development of advanced signal processing algorithms and systems for electronic warfare technologies, engaging with customers and leading multi-disciplinary teams.
Top Skills: C/C++MatlabMlflowPythonPyTorchTensorFlow
Reposted 8 Days AgoSaved
Easy Apply
Hybrid
Boston, MA
Easy Apply
244K-366K Annually
Expert/Leader
244K-366K Annually
Expert/Leader
Consumer Web • eCommerce • Marketing Tech • Retail • Software • Analytics • Generative AI
The Principal Engineer will lead enterprise scalability efforts, driving architectural changes, optimizing systems, and integrating AI for improved operational performance across multi-tenant SaaS platforms.
Top Skills: AIBack-PressureCachingCapacity PlanningMulti-Region ReadinessPartitioningPerformance EngineeringSharding
9 Days AgoSaved
In-Office
Boston, MA
173K-260K Annually
Senior level
173K-260K Annually
Senior level
Fintech • Information Technology • Payments • Sharing Economy • Financial Services • Cryptocurrency
As a Principal Software Engineer, you will design, develop, and implement complex software solutions, lead projects, and ensure compliance with standards in a cloud-first environment.
Top Skills: AWSCi/CdCSSDb2DevOpsHTMLJavaJSONNoSQLOracleRdsSpringSQLTerraformXML
Reposted 3 Days AgoSaved
In-Office
Boston, MA
75K-232K Annually
Senior level
75K-232K Annually
Senior level
Hardware • Semiconductor
The Principal Engineer - Process will support manufacturing and development of the Chip Scale Atomic Clock, focusing on process optimization, materials analysis, and lean manufacturing methodologies.
Top Skills: BomsErpLean ManufacturingPlmSix SigmaStatistical Methods
10 Days AgoSaved
Easy Apply
Hybrid
Boston, MA
Easy Apply
115K-155K Annually
Senior level
115K-155K Annually
Senior level
Cloud • Healthtech • Professional Services • Software • Pharmaceutical
The role involves designing, developing, and deploying efficient code, managing client communications, and providing technical guidance while ensuring quality control in clinical data services.
Top Skills: .NetAWSAzureBiBig DataBusiness ObjectsC#CognosData AnalyticsData LakeData ModellingData PipelinesData WarehouseDb2Elluminate® MapperETLHTMLIbm DatastageInformaticaJavaJreviewMicrostrategyMs SqlOraclePl/SqlPythonQlikQliksenseQlikviewRSparkSpotfireSQLSsrsT-SqlTableauTeradata
Reposted YesterdaySaved
Easy Apply
Remote
Boston, MA
Easy Apply
155K-220K Annually
Expert/Leader
155K-220K Annually
Expert/Leader
Cloud • Information Technology
The Principal Software Engineer will tackle platform-level challenges, assist team members, write secure and scalable code, and develop features for cloud storage solutions.
Top Skills: AIAnsibleBashCephContainerdDhcpDnsGoGrafanaHelmHelmfileKubernetesLdapLokiPostgresPrometheusPxeTerraform
Reposted 5 Days AgoSaved
Remote or Hybrid
Boston, MA
211K-284K Annually
Senior level
211K-284K Annually
Senior level
Artificial Intelligence • Automotive • Machine Learning • Transportation
As a Principal Engineer on the Behaviors team, you will guide the technology direction, lead complex initiatives, and mentor engineers to enhance autonomous vehicle capabilities through ML solutions.
Top Skills: C++CudaDeep LearningMachine LearningPythonPyTorch
2 Days AgoSaved
Easy Apply
Remote
Boston, MA
Easy Apply
298K-350K Annually
Expert/Leader
298K-350K Annually
Expert/Leader
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
The Principal Software Engineer will lead AI automation efforts at Coinbase, designing AI-driven systems, mentoring teams, and solving complex AI challenges to improve operations and developer productivity.
Top Skills: AIBackend EngineeringGenerative AiLlmMulti-Agent ArchitecturesOrchestration Tools
Reposted 11 Days AgoSaved
In-Office
Boston, MA
227K-284K Annually
Expert/Leader
227K-284K Annually
Expert/Leader
Artificial Intelligence • Cloud • Software • Infrastructure as a Service (IaaS)
Lead the technical direction of PaaS at DigitalOcean by architecting and implementing robust cloud-native services while mentoring engineers and ensuring system reliability.
Top Skills: C++GoJavaPython
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2 Days AgoSaved
Remote or Hybrid
Boston, MA
Expert/Leader
Expert/Leader
Automotive • Big Data • Information Technology • Robotics • Software • Transportation • Manufacturing
The Principal Software Engineer leads technical initiatives across GM's Digital Products, focusing on high-quality coding, architecture, mentoring engineers, and improving processes. The role requires guiding teams in delivering impactful solutions and sharing best practices.
Top Skills: C++GoJava
Reposted 6 Days AgoSaved
In-Office
Boston, MA
275K-412K Annually
Expert/Leader
275K-412K Annually
Expert/Leader
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
The Principal State Estimation Engineer will develop advanced sensor fusion algorithms for UAV navigation, integrating multiple sensor data and ensuring robust performance in contested environments.
Top Skills: C++11CudaLinux
Reposted 7 Days AgoSaved
In-Office
Boston, MA
157K-227K Annually
Expert/Leader
157K-227K Annually
Expert/Leader
Artificial Intelligence • Hardware • Automation • Manufacturing
Serve as technical authority for mixed-signal IC architecture and design, lead complex projects from concept to production, integrate analog and digital IP, drive methodology innovation, mentor engineers, and influence product and technology roadmaps.
Top Skills: AdcAnalog/Digital Ip IntegrationCmosDacLayout And Physical DesignMixed-Signal Ic DesignPllPower Management IcsSimulation And ModelingVerification Strategy
Reposted 12 Days AgoSaved
Hybrid
Boston, MA
106K-177K Annually
Senior level
106K-177K Annually
Senior level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
The Principal Packaging Engineer will oversee lab operations, manage packaging development projects, ensure compliance with standards, and provide strategic direction to teams.
Top Skills: Fda RegulationsGmpIso 13485
Reposted 12 Days AgoSaved
Hybrid
Boston, MA
168K-210K Annually
Senior level
168K-210K Annually
Senior level
Consumer Web • eCommerce • Software
As a Principal Software Engineer, you'll modernize DevX Pipelines, enhance CI/CD infrastructure, and promote software delivery efficiency.
Top Skills: BashCi/CdCloud EnvironmentsContainerizationGoJavaKubernetesPython
Reposted 7 Days AgoSaved
In-Office
Boston, MA
72K-189K Annually
Mid level
72K-189K Annually
Mid level
Healthtech • Biotech • Pharmaceutical
The Principal Engineer role involves developing LNP processes, conducting characterization studies, and supporting technology transfers for manufacturing readiness in the field of cardiovascular disease treatment.
Top Skills: High-Pressure MixingLipid Nanoparticle (Lnp)Lnp FormulationStatistical SoftwareTff
13 Days AgoSaved
Easy Apply
In-Office
Boston, MA
Easy Apply
204K-284K Annually
Expert/Leader
204K-284K Annually
Expert/Leader
Machine Learning • Security • Software • Analytics • Defense
The position involves reversing complex software/firmware, developing cybersecurity solutions, leading technical teams, and conducting vulnerability research, all while ensuring national security.
Top Skills: Afl++ArmBinary NinjaC/C++GhidraIda ProPythonQemuX86
Reposted 8 Days AgoSaved
In-Office or Remote
Boston, MA
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Healthtech • Pharmaceutical
Design and implement embedded software, improve process efficiency, resolve defects, and mentor junior staff while adhering to design controls.
Top Skills: C++Ci/CdLinux Shell ScriptingMicroc/CosQt FrameworkRtos (QnxThreadx)Vxworks
Reposted 4 Days AgoSaved
Easy Apply
Remote
Boston, MA
Easy Apply
158K-338K Annually
Senior level
158K-338K Annually
Senior level
Cloud • Security • Software • Cybersecurity • Automation
As a Principal Database Engineer, you will architect scalable PostgreSQL solutions, ensuring data reliability, performance, and collaborating with teams to build a robust data platform for GitLab's growth.
Top Skills: ElasticsearchPostgresTypescript
Reposted 4 Days AgoSaved
Remote
Boston, MA
256K-347K Annually
Expert/Leader
256K-347K Annually
Expert/Leader
Artificial Intelligence • Cloud • Consumer Web • Productivity • Software • App development • Data Privacy
Lead technical vision and execution for enterprise-scale AI, automation, and data initiatives. Architect scalable, secure AI systems and data pipelines, mentor engineers, drive cross-functional alignment, and deliver high-impact production solutions that improve productivity and business outcomes.
Top Skills: AIAutomated TestingAutomationCiData AnalyticsData PipelinesDistributed TrainingGoJavaMachine LearningNatural Language ProcessingPythonScalaVisualization
14 Days AgoSaved
In-Office or Remote
Boston, MA
250K-320K Annually
Expert/Leader
250K-320K Annually
Expert/Leader
Blockchain • Fintech • Payments • Financial Services • Cryptocurrency • Web3
The role involves leading Cloud Security strategy, enhancing security posture, managing infrastructure requirements, and collaborating across teams to ensure robust security in blockchain services.
Top Skills: AWSAzureBlockchainBurp SuiteCosmosEthereumGCPOwaspSolana
Reposted 5 Days AgoSaved
Easy Apply
Remote or Hybrid
Boston, MA
Easy Apply
150K-200K Annually
Senior level
150K-200K Annually
Senior level
Automotive • Big Data • Insurance • Software • Transportation
The Principal ML Engineer at Agero will develop and productionize a Dispatch System using ML models, optimize decision-making processes, and lead a team to improve operational performance.
Top Skills: AirflowAWSAzureGCPPythonPyTorchSagemakerSQLXgboost
Reposted 9 Days AgoSaved
In-Office
Boston, MA
75K-232K Annually
Senior level
75K-232K Annually
Senior level
Hardware • Semiconductor
The Principal Engineer will lead electronic systems development for atomic clocks, mentor engineers, and collaborate across teams on design execution.
Top Skills: AgileAnalog CircuitsCad ToolsDigital CircuitsEmbedded MicrocontrollersFpgaMixed Signal CircuitsRf DesignVerilogVhdl
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