Top Python Jobs in Boston, MA

Lead end-to-end technical initiatives for an IoT cloud platform, shaping architecture, strategy, and roadmap. Build and scale React/TypeScript frontends, Python backends, cloud infrastructure, databases, and data systems. Improve developer experience, operate production systems, establish engineering standards, mentor engineers, and influence technical direction across teams. Collaborate closely with product and design while delivering reliable systems for monitoring, debugging, and updating connected devices.

Lead software engineering projects and developer teams building cloud-based full-stack and distributed microservice solutions. Design service boundaries, APIs, reusable frameworks, and scalable systems using AWS and modern programming languages. Establish engineering standards, improve performance, reduce technical debt, and support operational excellence across Agile teams. Mentor engineers, evaluate emerging technologies, contribute to long-term technology strategy, and deliver financial technology solutions supporting regulatory and enterprise needs.

Leads technology projects and developers building full-stack, distributed microservice systems for financial technology. Designs cloud-based solutions, partners with architects on service boundaries and integration patterns, establishes engineering standards, reduces technical debt, and improves system performance. Provides technical leadership across Agile teams, mentors engineers, evaluates emerging technologies, and delivers solutions using modern programming languages, databases, containers, and cloud services.

Leads software engineering projects and developer teams building cloud-based full-stack and microservices solutions for financial technology. Responsibilities include technical leadership, mentoring, architecture collaboration, API and database development, cloud engineering, performance optimization, technical debt reduction, Agile delivery, and establishing engineering standards. The role uses Python and AWS alongside multiple programming languages, container orchestration, CI/CD, infrastructure as code, automated testing, observability, and AI-assisted development tools.

Build and own features for an AI-driven life sciences SaaS platform, from design and development through deployment, production support, and maintenance. Collaborate with product and engineering teams, solve complex technical problems, establish coding and AI-assisted engineering practices, conduct code reviews, and mentor engineers. The role requires production Python development, enterprise SaaS scalability expertise, and experience building high-volume cloud applications.

Modernize legacy SAS data-processing systems by translating logic into scalable, high-performance Python solutions. Build and optimize large-scale data pipelines using formats including SAS, Parquet, JSON, and SQL. Integrate PostgreSQL, implement parallel processing, automated testing, data validation, and quality assurance, and maintain well-documented code. Collaborate with IT specialists and stakeholders to validate requirements, troubleshoot issues, and deliver cloud-native modernization solutions.

Provides technical leadership for a team developing scalable decision-support applications. Leads software development across requirements, architecture, design, implementation, and delivery using Python, R, SAS, SQL, and database technologies. Models data sources and flows, develops security and operational frameworks, interprets analytical results, mentors colleagues, and presents recommendations to business and clinical stakeholders. The role also provides consultative support and leads complex analytical and software projects.

Own the technical foundation of a manufacturing software product, including auditing and hardening the existing codebase, designing architecture, shipping full-stack features, integrating ERP systems, evolving data models, building real-time capabilities, and managing infrastructure, deployment, and monitoring. The founding engineer will engage users, guide product decisions, establish engineering standards, help hire future engineers, and contribute to AI-powered features.

Leads multiple technology projects and engineering teams developing distributed microservices, full-stack systems, and cloud-native platforms. Provides technical leadership on architecture, system design, reliability, performance, platform roadmaps, and shared services. Partners with product managers and architects, mentors engineers, drives technology strategy, establishes coding standards, and delivers secure solutions supporting regulatory and compliance needs.

Build and scale Neuroscale’s backend platform for AI-powered recruiting workflows. Responsibilities include developing Python/FastAPI REST APIs, designing high-throughput systems, managing PostgreSQL, Redis, OpenSearch, Celery, and Temporal infrastructure, deploying services on AWS, maintaining containerized CI/CD pipelines, and supporting integrations, data pipelines, and asynchronous workflows. The role owns architecture and reliability decisions, mentors engineers, and collaborates with AI, product, and frontend teams in a high-ownership startup environment.

Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.

Own Telnyx’s global phone-number ordering pipeline, carrier integrations, regulatory automation, AI-powered order review, and Postgres data layer. Build reliable async Python services with retries, rollbacks, queues, SLA monitoring, document verification, auditability, and human escalation. Improve automation across dozens of vendors and 45+ countries while maintaining dashboards, analytics, and operational alerts across a large microservice estate.

Build and maintain AI-assisted full-stack platforms for manufacturing, spanning AWS infrastructure, Python Lambda services, Java microservices, agentic LLM workflows, and Angular interfaces. Develop event-driven architectures, APIs, retrieval and scoring systems, infrastructure as code, observability, CI/CD, and secure deployment strategies. Apply rigorous testing, specification-driven development, concurrency practices, and production reliability techniques across multi-repository systems. The role requires hands-on software development experience with enterprise server, storage, or networking products.

Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.

Work as a Python development intern building applications and APIs, processing and analyzing data, working with databases and data pipelines, contributing to system architecture, writing clean documented code, and collaborating with the team. Strong emphasis on backend development, SQL, ORMs, and REST API design with potential conversion to full-time.

Build and maintain Django-based web applications, design RESTful APIs, implement frontend features (HTML/CSS/JS), optimize performance and security, collaborate with cross-functional teams throughout the development lifecycle.

Lead the design, development, and implementation of resilient pricing tools using Python and cloud technologies. Improve automation, deployment reliability, testing, documentation, and technical standards. Coordinate complex projects, research new development practices, identify technical blockers, and mentor junior developers. Collaborate with stakeholders while developing expertise in insurance pricing and supporting applications built with technologies such as Streamlit, Flask, Docker, Kubernetes, and cloud compute.

Designs and builds scalable applications using React and Python, contributing to component development, data storage, deployment practices, performance optimization, testing, and client requirements analysis. The role collaborates with technical leaders, clients, and distributed teams in agile environments, using Git, code reviews, cloud platforms, databases, and AI-native development practices. U.S.-based travel to client sites is required.

Own end-to-end product features for a SaaS platform serving HR, therapists, and employees. Build, scale, and evolve frontend and backend components, lead architecture and standards, collaborate with design and product, and incorporate customer feedback and QA. Work in an early-stage startup environment with product-focused ownership.

Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.

Build and maintain Supabase’s public Python SDK across database, authentication, storage, realtime, and edge functions. Develop natural sync and async APIs, manage typing, packaging, testing, release automation, documentation, and issue triage. Collaborate with cross-functional teams and open-source contributors, support multiple Python environments, maintain WebSocket functionality, and design migration paths for API changes. Work autonomously in a remote, asynchronous environment while making the SDK accessible to developers and AI coding agents.

Evaluate AI coding agents such as Codex, Claude Code, and Cursor for engineering judgment, response quality, reasoning, explanations, and usefulness. Provide clear written and recorded feedback, distinguish quality levels, and help define standards for excellent AI-assisted development interactions. This contract role requires senior-level software engineering experience, strong Python or TypeScript/JavaScript skills, familiarity with modern AI development workflows, and excellent English communication.

Build, maintain, and scale e-commerce backend services using Python and Django. Develop REST APIs and features for catalogs, inventory, carts, checkout, orders, payments, and accounts. Integrate third-party services, optimize databases and performance, implement security controls, write tested code, resolve production issues, and collaborate on architecture, planning, reviews, deployment, and CI/CD.

Build and maintain full-stack applications that deliver AI/ML insights through backend services, REST APIs, containerized microservices, and high-performance front-end interfaces. Responsibilities include cloud-native development on Google Cloud or Azure, database management, testing, CI/CD automation, security, troubleshooting, and Agile collaboration.

Build and maintain Python backend services and serverless architectures for a restaurant operations platform. Ship end-to-end features, design robust systems, and help define product roadmap. Implement CI/CD and productionization, collaborate with product and GTM teams, and contribute to team culture and technical execution.