Top Python Jobs in Boston, MA

Reposted 12 Hours AgoSaved
Hybrid
Boston, MA
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead a team to develop distributed systems using Golang and Python on Kubernetes, collaborate on AI/ML solutions, and drive technological innovation.
Top Skills: AWSAzureCSSDockerGCPGoHTMLJavaJavaScriptKubernetesNoSQLPythonRdbmsSQLTypescript
Reposted 2 Days AgoSaved
Hybrid
Boston, MA
179K-225K Annually
Senior level
179K-225K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead a team of developers to build technology projects using microservices and full stack systems, focusing on cloud-based solutions and mentoring team members.
Top Skills: AWSAzureCSSDockerGCPGoHTMLJavaJavaScriptKubernetesPysparkPythonSQLTypescript
Reposted 7 Days AgoSaved
Easy Apply
Hybrid
Boston, MA
Easy Apply
90K-210K Annually
Senior level
90K-210K Annually
Senior level
Aerospace • Artificial Intelligence • Computer Vision • Machine Learning • Natural Language Processing • Software • Defense
Design, develop, and maintain scalable, reliable Python applications. Participate in design and code reviews, collaborate with engineers and data scientists, adopt microservices and containerization, follow Agile practices, and support deployment and integration for DoD-focused AI/ML and simulation projects.
Top Skills: AWSAzureContainerizationDevops ToolsDockerDocker-ComposeGCPGitKanbanKubernetesMicroservice ArchitecturePysparkPythonRelational DatabasesScrumSpark
Reposted 4 Days AgoSaved
Easy Apply
Remote or Hybrid
Boston, MA
Easy Apply
126K-248K Annually
Senior level
126K-248K Annually
Senior level
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills: Ai/Ml FrameworksMongoDBPypiPython
Reposted 14 Days AgoSaved
Hybrid
Boston, MA
209K-286K Annually
Senior level
209K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead a portfolio of technology projects with a team of developers to create solutions for regulatory needs, collaborating on cloud-based projects while mentoring engineers.
Top Skills: Amazon SagemakerAWSCSSDatabricksDockerGoHTMLJavaJavaScriptKubernetesLuaMcpPythonSQLTypescript
Reposted 25 Days AgoSaved
Hybrid
Boston, MA
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead diverse technology projects in distributed microservices and full stack systems, mentoring team members and collaborating with product managers on cloud-based solutions.
Top Skills: AWSCSSDockerGoGCPHTMLJavaJavaScriptKubernetesAzureNosql DatabasesOpen Source RdbmsPythonSQLTypescript
Reposted 11 Hours AgoSaved
In-Office
Boston, MA
60K-80K Annually
Senior level
60K-80K Annually
Senior level
Artificial Intelligence • Information Technology • Software • Consulting
Develop Python-based solutions performing SQL/CRUD operations, file extraction/transformation/generation (CSV, XML, JSON, PDF), and email integration. Work in an onsite/offshore model, collaborate with teams, communicate clearly, and perform under pressure for contract assignments.
Top Skills: CsvDatabaseEmail IntegrationJSONPdfPythonSQLXML
2 Days AgoSaved
In-Office
Boston, MA
100K-150K Annually
Senior level
100K-150K Annually
Senior level
Artificial Intelligence • Information Technology • Software • Consulting
Design, build, and maintain enterprise-grade Python applications and data-intensive services. Own architecture, performance tuning, data processing (batch and near-real-time), production troubleshooting, CI/CD and observability. Mentor engineers, conduct code reviews, collaborate with product/data/infrastructure teams, and support incident response to improve reliability and maintainability.
Top Skills: Ci/CdMs Sql ServerOraclePostgresPythonSybase
7 Days AgoSaved
In-Office or Remote
Boston, MA
110K-270K Annually
Senior level
110K-270K Annually
Senior level
Big Data • Cloud • Healthtech • Software • Big Data Analytics
Build and own features for a new AI-driven enterprise SaaS platform for life sciences. Design, develop, deploy, and support production Python services, collaborate on technical design, drive scalability, mentor engineers, and define engineering best practices with AI-assisted workflows.
Top Skills: AICloudFastapiGitPydanticPythonSaaS
7 Days AgoSaved
In-Office or Remote
Boston, MA
150K-300K Annually
Expert/Leader
150K-300K Annually
Expert/Leader
Big Data • Cloud • Healthtech • Software • Big Data Analytics
Lead design, build, deploy, and support a new AI-driven enterprise SaaS platform. Own features end-to-end, drive technical designs, mentor engineers, enforce best practices, perform expert code reviews, and ship scalable production Python services with AI-assisted engineering workflows.
Top Skills: AICloudFastapiGitPydanticPythonSaaS
Reposted An Hour AgoSaved
Remote or Hybrid
Boston, MA
Internship
Internship
Artificial Intelligence • Software • Consulting • Automation
Work as a Python development intern building applications and APIs, processing and analyzing data, working with databases and data pipelines, contributing to system architecture, writing clean documented code, and collaborating with the team. Strong emphasis on backend development, SQL, ORMs, and REST API design with potential conversion to full-time.
Top Skills: DjangoDjango OrmFastapiFlaskGitGitHTTPJSONMySQLNumpyPandasPostgresPythonRest ApiSQLSqlalchemySqlite
Reposted 11 Hours AgoSaved
Remote
Boston, MA
165K-215K Annually
Senior level
165K-215K Annually
Senior level
Legal Tech • Software
Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.
Top Skills: Async/AwaitClaude (Llm)Event-Driven ArchitectureFastapiGitlab Ci/CdMessage QueuesNew Relic ApmOctopus DeployPlaywrightPydantic V2Pydantic-AiPytestPython 3.12+ReactStructlogSyrupyTemporal
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Reposted 12 Hours AgoSaved
Remote
Boston, MA
200K-225K Annually
Senior level
200K-225K Annually
Senior level
Artificial Intelligence • eCommerce • Software
Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.
Top Skills: APIsAWSAzureDockerGCPKubernetesLlmsMachine LearningNoSQLPythonSQL
YesterdaySaved
Remote
Boston, MA
103K-150K Annually
Mid level
103K-150K Annually
Mid level
Big Data • Machine Learning • Software • Analytics
Develop and maintain Alteryx Intelligent Services cloud and on‑prem products. Own design, implementation, testing, and contribute to DevOps pipelines and quality frameworks. Participate in code reviews, mentor teammates, collaborate with Product Management, and focus on delivering customer-centric, well-tested, performant software.
Top Skills: APIsCloudDevOpsGitPythonReactSdks
Reposted YesterdaySaved
In-Office or Remote
Boston, MA
Mid level
Mid level
Healthtech
Own end-to-end product features for a SaaS platform serving HR, therapists, and employees. Build, scale, and evolve frontend and backend components, lead architecture and standards, collaborate with design and product, and incorporate customer feedback and QA. Work in an early-stage startup environment with product-focused ownership.
Top Skills: Next.JsPythonReact
Reposted 10 Days AgoSaved
In-Office
Boston, MA
115K-195K Annually
Senior level
115K-195K Annually
Senior level
Information Technology • Software • Database
Maintain and improve the LangChain Python package, enhance documentation, assist users, and build example applications.
Top Skills: Python
Reposted 2 Days AgoSaved
Remote
Boston, MA
100K-200K Annually
Senior level
100K-200K Annually
Senior level
Artificial Intelligence • HR Tech • Information Technology • Software
As a Founding Staff Software Engineer, you will lead the design and development of robust backend systems and APIs, optimize large-scale data workflows, and mentor a growing engineering team.
Top Skills: AWSCeleryFastapiOpensearchPostgresPythonRedisTemporal
Reposted 12 Days AgoSaved
In-Office
Boston, MA
120K-228K Annually
Senior level
120K-228K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, implement, and scale event-driven, distributed backend systems in Python on AWS to process and enrich large-scale document and media datasets. Lead technical projects, mentor engineers, integrate ML/LLM components, optimize performance, maintain observability, and collaborate with Data Science, ML Engineering, and Product to deliver reliable high-throughput content processing services.
Top Skills: AirflowAWSCloudwatchDatabricksDatadogEcsElasticacheLambdaLlmMachine LearningPythonScalaSnsSparkSqsTerraform
Reposted 14 Days AgoSaved
In-Office
Boston, MA
153K-229K Annually
Senior level
153K-229K Annually
Senior level
Healthtech
Lead the technical direction for integrating algorithms on the Prism Mapping platform, focusing on real-time signal pipelines and optimization strategies. Collaborate with teams to ensure robust clinical performance and timely delivery of new capabilities.
Top Skills: C++Python
Reposted 14 Days AgoSaved
In-Office
Boston, MA
125K-187K Annually
Senior level
125K-187K Annually
Senior level
Healthtech
As a Senior Software Engineer, you'll develop signals and algorithm interfaces, collaborate with developers, optimize algorithms, and mentor engineers in a regulated environment.
Top Skills: C++Python
Reposted 4 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Artificial Intelligence • Logistics • Software • Transportation
Design, develop, deploy, monitor, and support APIs and system integrations (Salesforce, REST, third-party). Work directly with clients to gather requirements, troubleshoot and optimize integrations, operate solutions in AWS, collaborate with teams, and mentor junior developers.
Top Skills: Aws Api GatewayAws EcsAws LambdaAws RdsPythonRest ApiSalesforceSnsSqsTerraform
Reposted 4 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Information Technology • Logistics • Transportation • Consulting
Build and ship full‑stack features for transportation management and other client products. Design and implement APIs and UIs, collaborate with product and design, own delivery, write modular testable code, troubleshoot and iterate quickly, and mentor peers.
Top Skills: .NetC#Ci/CdDevOpsDockerElectronFastapiGraphQLJavaJavaScriptLlmsLookmlMlMongoDBMySQLNode.jsPythonReact NativeReactRestSpringTypescriptVue
Reposted 4 Days AgoSaved
Remote
Boston, MA
Junior
Junior
Artificial Intelligence • Blockchain • Digital Media • Information Technology
Develop and maintain Python applications focusing on iterators/generators/streams, concurrency (multithreading, non-blocking I/O), and high-precision numeric handling. Work with JSON/XML, REST and SOAP APIs, ACID-compliant databases, message brokers/queues, and produce clean, SOLID code. Unit and integration testing experience is beneficial.
Top Skills: Acid-Compliant DatabasesDecimal ModuleFractions ModuleGeneratorsIntegration TestingIteratorsJSONMessage BrokersMessage QueuesMulti-ThreadingNon-Blocking I/OParallelismPythonRegular ExpressionsRestSoapStreamsUnit TestingXML
Reposted 4 Days AgoSaved
Remote
Boston, MA
125K-200K Annually
Senior level
125K-200K Annually
Senior level
Software • Cybersecurity
The Forward Deployed Engineer will serve as a technical bridge between clients and engineering teams, writing custom code and integrations, while ensuring customer success with Socket's security platform through strong relationships and expert technical guidance.
Top Skills: Automation ScriptsCi/CdDevOpsPythonSastWebhook Implementations
Reposted 5 Days AgoSaved
In-Office or Remote
Boston, MA
150K-200K Annually
Mid level
150K-200K Annually
Mid level
Artificial Intelligence • Food • Software • Hospitality
Build and maintain Python backend services and serverless architectures for a restaurant operations platform. Ship end-to-end features, design robust systems, and help define product roadmap. Implement CI/CD and productionization, collaborate with product and GTM teams, and contribute to team culture and technical execution.
Top Skills: Aws LambdaAws ServerlessAws Step FunctionsCi/CdGoJavaJavaScriptPythonReactTypescript
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