Top Python Jobs in Boston, MA

Reposted YesterdaySaved
Hybrid
Boston, MA
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead diverse technology projects in distributed microservices and full stack systems, mentoring team members and collaborating with product managers on cloud-based solutions.
Top Skills: AWSCSSDockerGoGCPHTMLJavaJavaScriptKubernetesAzureNosql DatabasesOpen Source RdbmsPythonSQLTypescript
Reposted 2 Days AgoSaved
Hybrid
Boston, MA
209K-286K Annually
Senior level
209K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead a portfolio of technology projects with a team of developers to create solutions for regulatory needs, collaborating on cloud-based projects while mentoring engineers.
Top Skills: Amazon SagemakerAWSCSSDatabricksDockerGoHTMLJavaJavaScriptKubernetesLuaMcpPythonSQLTypescript
Reposted 9 Days AgoSaved
Easy Apply
Hybrid
Boston, MA
Easy Apply
90K-210K Annually
Senior level
90K-210K Annually
Senior level
Aerospace • Artificial Intelligence • Computer Vision • Machine Learning • Natural Language Processing • Software • Defense
Design and develop scalable software applications in Python, collaborate with teams, and ensure code quality for critical defense projects.
Top Skills: AgileAWSAzureDockerDocker-ComposeGCPGitKubernetesPysparkPythonSpark
13 Days AgoSaved
Hybrid
Boston, MA
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead a team to develop distributed systems using Golang and Python on Kubernetes, collaborate on AI/ML solutions, and drive technological innovation.
Top Skills: AWSAzureCSSDockerGCPGoHTMLJavaJavaScriptKubernetesNoSQLPythonRdbmsSQLTypescript
Reposted 15 Days AgoSaved
Hybrid
Boston, MA
179K-225K Annually
Senior level
179K-225K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead a team of developers to build technology projects using microservices and full stack systems, focusing on cloud-based solutions and mentoring team members.
Top Skills: AWSAzureCSSDockerGCPGoHTMLJavaJavaScriptKubernetesPysparkPythonSQLTypescript
Reposted YesterdaySaved
Remote
Boston, MA
Senior level
Senior level
Artificial Intelligence • Information Technology • Professional Services • Software
The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.
Top Skills: CSSDjangoDockerFastapiFlaskGitGnu/LinuxHTMLJavaScriptMongoDBMySQLNode.jsOraclePostgresPythonReactSvnVue
Reposted 3 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Logistics • Software • Transportation
The Principal Python Engineer will design, build, and maintain backend services and APIs, focusing on system reliability and engineering quality. The role involves working with databases, applying DevOps practices, and leveraging AI for development efficiency.
Top Skills: DockerFastapiKubernetesPostgresPulumiPythonTemporalVue
Reposted 3 Days AgoSaved
In-Office or Remote
Boston, MA
Senior level
Senior level
Cloud • Software
The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.
Top Skills: CC++DockerGoKubernetesLinuxNoSQLPythonRustSQL
4 Hours AgoSaved
In-Office
Boston, MA
120K-228K Annually
Senior level
120K-228K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, implement, and scale event-driven, distributed backend systems in Python on AWS to process and enrich large-scale document and media datasets. Lead technical projects, mentor engineers, integrate ML/LLM components, optimize performance, maintain observability, and collaborate with Data Science, ML Engineering, and Product to deliver reliable high-throughput content processing services.
Top Skills: AirflowAWSCloudwatchDatabricksDatadogEcsElasticacheLambdaLlmMachine LearningPythonScalaSnsSparkSqsTerraform
4 Hours AgoSaved
In-Office
Boston, MA
104K-196K Annually
Senior level
104K-196K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, build, and optimize event-driven, distributed backend systems and APIs in Python for large-scale content metadata extraction and enrichment. Deploy and operate resilient AWS-based pipelines, collaborate with ML teams to integrate models, and ensure system performance, observability, and data integrity.
Top Skills: AirflowAws CloudwatchAws EcsAws ElasticacheAws LambdaAws SnsAws SqsDatabricksDatadogLlmMachine LearningPythonScalaSparkTerraform
4 Hours AgoSaved
In-Office
Boston, MA
120K-228K Annually
Senior level
120K-228K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, build, and scale event-driven, distributed backend systems in Python to extract and enrich metadata at massive scale. Lead architecture, mentor engineers, integrate ML/LLM components, optimize performance, and ensure observability and reliability across AWS-based pipelines.
Top Skills: AirflowAws CloudwatchAws EcsAws ElasticacheAws LambdaAws SnsAws SqsDatabricksDatadogLlmMachine LearningPythonScalaSparkTerraform
Reposted 18 Days AgoSaved
Easy Apply
Remote or Hybrid
Boston, MA
Easy Apply
126K-248K Annually
Senior level
126K-248K Annually
Senior level
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills: Ai/Ml FrameworksMongoDBPypiPython
New

Track Smarter, Apply Better.

Ditch the spreadsheets. Organize your job search with our freeApplication Tracker.

Use For Free
Application Tracker Preview
Reposted YesterdaySaved
In-Office or Remote
Boston, MA
150K-300K Annually
Expert/Leader
150K-300K Annually
Expert/Leader
Big Data • Cloud • Healthtech • Software • Big Data Analytics
As a Principal Software Engineer, you will lead the development of an AI-driven platform for life sciences, owning feature implementation, driving solutions, mentoring engineers, and promoting best practices.
Top Skills: FastapiGitPydanticPython
Reposted YesterdaySaved
In-Office
Boston, MA
170K-201K Annually
Senior level
170K-201K Annually
Senior level
eCommerce • Hardware • Healthtech • Software
Lead the design and development of a Python SDK for ultrasound imaging devices, collaborating cross-functionally and ensuring robustness and performance in a healthcare context.
Top Skills: CC++DjinniPythonSwig
21 Days AgoSaved
Remote
Boston, MA
Mid level
Mid level
Information Technology
Concept Plus seeks a Junior Python Developer to enhance enterprise-scale applications, focusing on backend development, DevSecOps practices, and secure coding under senior guidance.
Top Skills: Ci/CdGitPyodidePythonRest ApisWebassembly
8 Days AgoSaved
In-Office
Boston, MA
107K-216K Annually
Senior level
107K-216K Annually
Senior level
Fintech
The Principal Python Backend Engineer will design and build high-performance backend systems for AI/ML services, focus on clean code, maintainability, and automation, while leading teams through a collaborative and innovative approach.
Top Skills: AWSCi/CdDockerKubernetesPython
7 Hours AgoSaved
Remote
Boston, MA
165K-215K Annually
Senior level
165K-215K Annually
Senior level
Legal Tech • Software
Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.
Top Skills: Async/AwaitClaude (Llm)Event-Driven ArchitectureFastapiGitlab Ci/CdMessage QueuesNew Relic ApmOctopus DeployPlaywrightPydantic V2Pydantic-AiPytestPython 3.12+ReactStructlogSyrupyTemporal
YesterdaySaved
Remote
Boston, MA
130K-165K Annually
Senior level
130K-165K Annually
Senior level
HR Tech • Legal Tech • Software • Consulting
Design, implement, and maintain SaaS features using Python and React on AWS. Lead system design, code reviews, CI/CD pipelines, AI-integrated development (LLMs and AI coding agents), prompt engineering, testing (Cypress), and on-call production support. Mentor teammates and ensure secure, scalable, well-documented software.
Top Skills: AWSCicdClaude CodeCodexContainerized EnvironmentsCypressDevin.AiLlmMcpMySQLPython 3.11ReactRestful Apis
Reposted YesterdaySaved
In-Office or Remote
Boston, MA
Mid level
Mid level
Cloud • Software
We are seeking a software engineer to build and validate resilient distributed systems, enhance CI pipelines, and improve testing strategies for cloud applications.
Top Skills: AWSCircleCIGithub CiGoJenkinsKubernetesOpenstackPythonTerraform
Reposted YesterdaySaved
In-Office or Remote
Boston, MA
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Machine Learning • Other
The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.
Top Skills: AWSCi/CdDockerPostgresPostgresql/PostgisPythonTerraform
Reposted 3 Days AgoSaved
In-Office or Remote
Boston, MA
2K-2K Annually
Mid level
2K-2K Annually
Mid level
Cloud • Software
As a Python and Kubernetes Software Engineer, you will develop data analytics solutions using open source tools, collaborating with a distributed team.
Top Skills: AirflowApache SupersetApache TrinoAWSAzureClickhouseDbtDockerDvcFeastGCPKubernetesLxdMlflowPythonTemporal
4 Days AgoSaved
Remote
Boston, MA
50K-120K Hourly
Mid level
50K-120K Hourly
Mid level
Artificial Intelligence • HR Tech • Professional Services • Software
Develop and enhance Panda3D-based 3D game simulations for AI training. Implement and maintain Python and C++ code, ensure cross-platform performance, use GitHub workflows, document architecture, and collaborate with teams through reviews and discussions.
Top Skills: 3D Graphics PipelineC++GitGitPanda3DPythonSimulation Mechanics
5 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Healthtech • Software
Lead backend development on the scheduling platform modernization, contribute across products, write APIs, and drive AI-accelerated software development workflows.
Top Skills: .NetAgent OrchestrationAi-Assisted DevelopmentLlm ToolingPython
5 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Healthtech • Software
Lead backend development on the scheduling platform modernization. Contribute across Python and .NET ecosystems, write APIs, review code, and support AI-accelerated development workflows while collaborating in a remote team environment.
Top Skills: .NetAi-Assisted Development WorkflowsClaude CodeLlm ToolingMulti-Agent SystemsPython
6 Days AgoSaved
Remote
Boston, MA
Mid level
Mid level
Information Technology • Professional Services
Seeking a Full Stack Engineer to develop and scale the platform using React and Python. Responsibilities include building frontend applications, developing APIs, managing workflows, and optimizing databases.
Top Skills: Ci/CdDockerGCPPlaywrightPostgresPythonReactTailwindTemporalTypescriptVitest
All Filters
JobType
New Jobs
Job Category
Experience
Industry
Company Name
Company Size

Sign up now Access later

Create Free Account