Top Python Jobs in Boston, MA

22 Days AgoSaved
Hybrid
Boston, MA
179K-246K Annually
Mid level
179K-246K Annually
Mid level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead a team of software developers and a portfolio of technology projects focused on regulatory risk solutions. Build distributed microservices, full-stack systems, and cloud-based applications using modern programming languages, databases, containers, and AWS services. Mentor engineers, evaluate emerging technologies, collaborate with product managers, and deliver resilient solutions in an agile environment.
Top Skills: AWSDockerGoGCPHTML/CSSJavaJavaScriptKubernetesAzureNode.jsNoSQLOpen Source FrameworksPythonRdbmsReactSQLTypescript
Reposted One Month AgoSaved
Easy Apply
Hybrid
Boston, MA
Easy Apply
90K-210K Annually
Senior level
90K-210K Annually
Senior level
Aerospace • Artificial Intelligence • Computer Vision • Machine Learning • Natural Language Processing • Software • Defense
Design, develop, and maintain scalable, reliable Python applications. Participate in design and code reviews, collaborate with engineers and data scientists, adopt microservices and containerization, follow Agile practices, and support deployment and integration for DoD-focused AI/ML and simulation projects.
Top Skills: AWSAzureContainerizationDevops ToolsDockerDocker-ComposeGCPGitKanbanKubernetesMicroservice ArchitecturePysparkPythonRelational DatabasesScrumSpark
7 Days AgoSaved
Hybrid
Boston, MA
160K-210K Annually
Senior level
160K-210K Annually
Senior level
Internet of Things • Semiconductor
Lead end-to-end technical initiatives for an IoT cloud platform, shaping architecture, strategy, and roadmap. Build and scale React/TypeScript frontends, Python backends, cloud infrastructure, databases, and data systems. Improve developer experience, operate production systems, establish engineering standards, mentor engineers, and influence technical direction across teams. Collaborate closely with product and design while delivering reliable systems for monitoring, debugging, and updating connected devices.
Top Skills: AWSClickhouseEmbedded SystemsHigh-Throughput Data PipelinesIotMessaging SystemsObservabilityPostgresPythonReactTypescript
One Month AgoSaved
Hybrid
Boston, MA
115K-190K Annually
Mid level
115K-190K Annually
Mid level
eCommerce • Healthtech • Pet • Retail • Pharmaceutical
Design, develop, and deploy high-performance distributed optimization, data, and simulation systems. Collaborate with cross-functional teams, resolve data quality and production issues, write maintainable code with TDD, unit tests, and CI/CD, and advocate engineering best practices.
Top Skills: Ci/CdPythonSQLUnit TestingVersion Control
Senior level
Artificial Intelligence • Logistics • Software • Transportation
Designs and develops APIs, system integrations, and AI-agent workflows for enterprise applications. Builds integrations with platforms such as Salesforce and REST APIs, deploys and supports solutions on AWS, and develops AI-powered automation using LLMs, tool calling, and multi-step workflows. The role includes client requirements gathering, troubleshooting, reliability optimization, cross-functional collaboration, and mentoring junior developers.
Top Skills: Ai AgentsApi GatewayAWSEcsLambdaLarge Language Models (Llms)PythonRdsRest ApisSalesforceSnsSqsTerraform
Reposted YesterdaySaved
Remote or Hybrid
Boston, MA
Internship
Internship
Artificial Intelligence • Software • Consulting • Automation
Work as a Python development intern building applications and APIs, processing and analyzing data, working with databases and data pipelines, contributing to system architecture, writing clean documented code, and collaborating with the team. Strong emphasis on backend development, SQL, ORMs, and REST API design with potential conversion to full-time.
Top Skills: DjangoDjango OrmFastapiFlaskGitGitHTTPJSONMySQLNumpyPandasPostgresPythonRest ApiSQLSqlalchemySqlite
2 Days AgoSaved
Remote
Boston, MA
140K-200K Annually
Senior level
140K-200K Annually
Senior level
Cloud • Software • Cybersecurity
Designs, develops, deploys, and operates scalable Go and Python microservices in distributed production environments. Responsibilities include API design, Kubernetes deployment, monitoring, scaling, troubleshooting incidents, system architecture, security, testing, code reviews, and continuous improvements to development processes and infrastructure. The role requires end-to-end service ownership, strong Linux and Docker expertise, observability knowledge, and experience with reliability, performance, and CI/CD practices.
Top Skills: AWSAzureCi/CdClickhouseDatadogDjangoDockerElkFastapiFlaskGCPGitGoGrafanaJwtKeycloakKubernetesLinuxMySQLOauth 2.0OpentelemetryPrometheusPythonRedisRestful Apis
Reposted 2 Days AgoSaved
Remote
Boston, MA
Mid level
Mid level
Artificial Intelligence • Computer Vision • Machine Learning • Software
Build and maintain Django-based web applications, design RESTful APIs, implement frontend features (HTML/CSS/JS), optimize performance and security, collaborate with cross-functional teams throughout the development lifecycle.
Top Skills: CSSDjangoGitHTMLJavaScriptMySQLPostgresPythonRestful Apis
2 Days AgoSaved
Remote or Hybrid
Boston, MA
140K-155K Annually
Mid level
140K-155K Annually
Mid level
eCommerce • Information Technology • Machine Learning • Marketing Tech • Database • Analytics • Big Data Analytics
Build and maintain reliable data pipelines, APIs, integrations, and event-driven or batch processing systems. Transform data from advertising, ecommerce, order management, and event sources while improving monitoring, freshness, performance, and scalability. Collaborate with data engineering, infrastructure, product, and business teams to extend the integration platform in a cloud-native, multi-tenant environment.
Top Skills: AirflowAmazon ApisAmazon RedshiftBigQueryCdpsCrmsDagsterDockerErp SystemsGdprGraphQLKubernetesOauth 2.0PrefectPythonRest ApisShopifySnowflakeSoc 2SQLWebhooks
2 Days AgoSaved
Remote or Hybrid
Boston, MA
140K-155K Annually
Mid level
140K-155K Annually
Mid level
eCommerce • Information Technology • Machine Learning • Marketing Tech • Database • Analytics • Big Data Analytics
Build backend services, APIs, data-processing systems, and frontend features for Northbeam’s marketing intelligence platform. Work on experimentation, near-real-time data infrastructure, AI-powered workflows, data integrations, RBAC, and end-to-end product delivery. Collaborate with data scientists, product managers, designers, and senior engineers while contributing across backend, frontend, pipelines, and infrastructure in a fast-moving environment.
Top Skills: AIAPIsData Processing SystemsDistributed SystemsMachine LearningMicroservicesNear-Real-Time Data IngestionPythonRbacReactTypescript
2 Days AgoSaved
Remote or Hybrid
Boston, MA
190K-220K Annually
Senior level
190K-220K Annually
Senior level
eCommerce • Information Technology • Machine Learning • Marketing Tech • Database • Analytics • Big Data Analytics
Lead backend-focused software architecture and development across distributed systems, data ingestion, experimentation platforms, AI workflows, and product capabilities. Build primarily in Python while contributing to React and TypeScript frontend work. Translate ambiguous product needs into scalable production systems, guide technical direction, partner with product and data teams, mentor engineers, and improve engineering practices.
Top Skills: Ai WorkflowsAPIsData Processing SystemsDistributed SystemsMicroservicesNear-Real-Time Data InfrastructurePythonReactRole-Based Access Control (Rbac)Typescript
Reposted 2 Days AgoSaved
In-Office or Remote
Boston, MA
Mid level
Mid level
Healthtech
Own end-to-end product features for a SaaS platform serving HR, therapists, and employees. Build, scale, and evolve frontend and backend components, lead architecture and standards, collaborate with design and product, and incorporate customer feedback and QA. Work in an early-stage startup environment with product-focused ownership.
Top Skills: Next.JsPythonReact
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12 Days AgoSaved
In-Office
Boston, MA
Senior level
Senior level
Information Technology • Software • Consulting
Develop software applications in Python, integrate third-party and portfolio management APIs, build ETL and data integration solutions, process XML and JSON, work with MySQL and complex SQL, extract information from PDF and Excel documents, conduct code reviews, and mentor developers.
Top Skills: AllvueDjangoETLExcelFastapiJSONMySQLPdfPythonRest ApisSQLXMLZope Rest Framework
Reposted 2 Days AgoSaved
Remote or Hybrid
Boston, MA
Senior level
Senior level
Digital Media • Social Media • Software • Design
Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.
Top Skills: Python
Senior level
Artificial Intelligence • Machine Learning • Natural Language Processing • Software • Generative AI
Develop and maintain open-source Python frameworks and ML developer tools, architect scalable libraries, grow early-stage projects, build real-time streaming capabilities, integrate modern frontend technologies, and collaborate with open-source contributors and the broader developer community.
Top Skills: JavaScriptPythonReactSvelteTypescriptWebrtcWebsockets
Reposted 15 Days AgoSaved
In-Office
Boston, MA
153K-229K Annually
Senior level
153K-229K Annually
Senior level
Healthtech
Lead the technical direction for integrating algorithms on the Prism Mapping platform, focusing on real-time signal pipelines and optimization strategies. Collaborate with teams to ensure robust clinical performance and timely delivery of new capabilities.
Top Skills: C++Python
Reposted 15 Days AgoSaved
In-Office
Boston, MA
125K-187K Annually
Senior level
125K-187K Annually
Senior level
Healthtech
As a Senior Software Engineer, you'll develop signals and algorithm interfaces, collaborate with developers, optimize algorithms, and mentor engineers in a regulated environment.
Top Skills: C++Python
16 Days AgoSaved
In-Office
Boston, MA
Entry level
Entry level
Information Technology • Professional Services • Consulting
Develop scalable Python-based full-stack applications, data pipelines, and information infrastructure for multidisciplinary research and advanced analytics. Responsibilities include ingesting structured and unstructured data, contributing to big-data ecosystem design, building database-backed websites and RESTful services, using SQL and NoSQL technologies, and developing JavaScript frontends with modern frameworks.
Top Skills: AngularjsAnsibleBackboneCassandraCouchdbDjangoDurandalEmberFlaskJavaScriptKnockoutjsMongoDBMySQLNode.jsPandasPostgresPythonRestful Web ServicesRuby On RailsSalt
7 Days AgoSaved
Remote
Boston, MA
130K-130K Annually
Mid level
130K-130K Annually
Mid level
Artificial Intelligence • HR Tech • Professional Services • Software
Build and validate challenging codebase-exploration tasks for AI agents using production Python repositories. Responsibilities include investigating runtime behavior and issue history, rewriting questions, refining rubrics and foils, running validation workflows, documenting solutions, and addressing expert review. The role is fully remote, asynchronous, contract-based, and task-paid, with work performed in a dedicated Studio environment.
Top Skills: CertbotCommand-Line ToolingContainersCoverage.PyDjangoGitMesonMitmproxyMypyOktaPipPythonScrapySqlfluffSympyTornadoTwistedWerkzeug
Reposted 9 Days AgoSaved
In-Office or Remote
Boston, MA
150K-200K Annually
Mid level
150K-200K Annually
Mid level
Artificial Intelligence • Food • Software • Hospitality
Build and maintain Python backend services and serverless architectures for a restaurant operations platform. Ship end-to-end features, design robust systems, and help define product roadmap. Implement CI/CD and productionization, collaborate with product and GTM teams, and contribute to team culture and technical execution.
Top Skills: Aws LambdaAws ServerlessAws Step FunctionsCi/CdGoJavaJavaScriptPythonReactTypescript
12 Days AgoSaved
Remote
Boston, MA
145K-150K Annually
Senior level
145K-150K Annually
Senior level
Digital Media • Software
Modernize legacy SAS data-processing systems by translating logic into scalable, high-performance Python solutions. Build and optimize large-scale data pipelines using formats including SAS, Parquet, JSON, and SQL. Integrate PostgreSQL, implement parallel processing, automated testing, data validation, and quality assurance, and maintain well-documented code. Collaborate with IT specialists and stakeholders to validate requirements, troubleshoot issues, and deliver cloud-native modernization solutions.
Top Skills: AWSDaskGitJSONLinuxMultiprocessingParquetPostgresPysparkPythonSASSQL
15 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Software
Lead the design, development, and operation of production-grade automation, agent frameworks, and CI/CD pipelines supporting documentation, localization, and language operations. Integrate platforms through REST APIs and MCPs, apply LLM capabilities responsibly, improve reliability and scalability, establish reusable standards, and mentor engineers. The role is fully remote in the US, with preferred Eastern or Central time zone availability.
Top Skills: Ai AgentsAzure DevopsChatgptCi/CdContainerizationCursorGitGitGithub ActionsGithub CopilotGitlab CiJenkinsJIRALinearLlmsMcpsMicrosoft CopilotObservabilityPythonRest Apis
Reposted One Month AgoSaved
Easy Apply
Remote or Hybrid
Boston, MA
Easy Apply
126K-248K Annually
Senior level
126K-248K Annually
Senior level
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills: Ai/Ml FrameworksMongoDBPypiPython
18 Days AgoSaved
Remote
Boston, MA
100K-130K Annually
Senior level
100K-130K Annually
Senior level
Healthtech • Pharmaceutical • Hospitality
Build and maintain scalable backend applications, serverless functions, microservices, data workflows, ETL pipelines, and cloud-native architectures using Python and AWS. Manage databases, APIs, batch jobs, and real-time integrations while optimizing performance, scalability, security, compliance, and cost. Collaborate with product, engineering, analytics, and data teams; contribute to architecture, CI/CD, infrastructure automation, development standards, and technical mentorship. Healthcare claims data experience is required.
Top Skills: Amazon Api GatewayAmazon AuroraAmazon KinesisAmazon RdsAmazon RedshiftAmazon S3AWSAws GlueAws LambdaAws Step FunctionsCi/CdData LakesData WarehousesDevOpsETLHipaaHl7Infrastructure As CodeMicroservicesMySQLPostgresPythonServerless ComputingSQLStored Procedures
23 Days AgoSaved
Remote
Boston, MA
Junior
Junior
Software
Build and maintain scalable Python-based AI applications under senior guidance. Assist with requirements, feature implementation, data modeling using Pydantic, code reviews, troubleshooting, testing, and CI/CD. The role requires collaboration, communication, and willingness to learn modern Python tools, frameworks, and libraries. Candidates should understand object-oriented programming, REST APIs, large language models, and AI coding tools. The position is fully remote within the United States.
Top Skills: AWSAzureCi/CdClaude CodeGCPGitGithub CopilotJavaScriptLarge Language Models (Llms)Node.jsPydanticPythonRest ApisTypescript
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