Top Senior Systems Engineer Jobs in Boston, MA

Lead cybersecurity engineering and software development for HPE Block Storage products. Responsibilities include designing security architecture, implementing cybersecurity features, supporting certification and compliance activities, evaluating security technologies, remediating vulnerabilities, influencing security standards, and mentoring engineers. The role requires expertise in cybersecurity engineering, software development, compliance frameworks, scalable security solutions, and technical leadership.

Provides Oracle-based digital finance and systems integration consulting for clients. Responsibilities include analyzing financial processes, designing and implementing business application solutions, integrating enterprise platforms, supporting NetSuite adoption, managing projects and budgets, applying agile methodologies, documenting deliverables, and maintaining stakeholder relationships. The role also provides client training, technical support, and optimization advice across financial planning, reporting, and operations.

Lead battery system architecture, integration, validation, and sustaining engineering for wearable products. Develop requirements, power budgets, verification strategies, reliability assessments, and manufacturing controls. Integrate charging, fuel gauging, protection, thermal sensing, firmware, and mechanical systems. Investigate failures using test data and telemetry, collaborate with engineering and external partners, qualify designs, support compliance, and evaluate battery technologies. Travel up to 15% to suppliers, manufacturing partners, and testing facilities.

Lead and contribute to the design, integration, deployment, and sustainment of mission-focused systems. Translate stakeholder needs into technical requirements, architectures, interface definitions, deployment patterns, and operational processes. Partner with software engineers and data scientists to integrate applications, data pipelines, infrastructure, and external systems. Support testing, verification, troubleshooting, operational readiness, documentation, and reliability improvements for secure, scalable, data-intensive systems.

Designs system architectures, requirements, interfaces, and performance metrics for robotaxi systems spanning autonomy, remote operations, fleet orchestration, mapping, and customer-facing software. Evaluates system performance through data pipelines, simulation, verification, and validation campaigns; collaborates across engineering and operations teams; documents complex workflows; and supports safety-focused autonomous vehicle deployment.

Leads systems engineering for wearable hardware programs, including requirements management, system architecture, interface definitions, verification and validation, technical documentation, design reviews, risk resolution, and cross-functional integration across electrical, mechanical, firmware, signal processing, manufacturing, and product teams. Provides technical leadership and mentorship while collaborating with partners, suppliers, and manufacturers through up to 15% domestic and international travel.

Provides presales technical support for HPE Networking solutions serving Rhode Island state government and higher education accounts. Designs complex networking solutions, delivers presentations and demonstrations, supports proposals and proofs of concept, manages technical customer and partner relationships, and collaborates with territory managers to advance sales opportunities. The role requires expertise in WLAN, switching, NAC/AAA, routing, LAN/WAN technologies, consultative selling, solution design, and executive-level customer engagement.

Senior Systems Engineer supporting Air Force air defense sensor programs across the full systems lifecycle. Responsibilities include requirements and architecture analysis, technical baseline and configuration management, system validation, trade studies, risk management, technical reviews, acquisition support, integration, deployment, sustainment, and systems engineering documentation. The role requires extensive DoD acquisition experience, MBSE, modeling and simulation, verification and validation, and familiarity with network, embedded, cloud, and virtualization architectures.

Develop and lead mechanical and ocean engineering solutions for uncrewed undersea systems, including vehicles, buoys, pressure vessels, hydrodynamic structures, and sensor subsystems. Responsibilities include modeling and simulation, prototyping, fabrication, integration, testing, peer reviews, technical documentation, and collaboration across mechanical, electrical, acoustic, software, and systems teams. The role supports advanced defense and ISR research involving fielded undersea systems.

Leads system integration, verification, validation, defect analysis, and remediation for medical device products. Translates user needs and system requirements into traceable test cases, executes system-level testing, analyzes risks and results, supports DFMEA and risk-control verification, and ensures compliance with medical device standards and regulations. Collaborates with cross-functional teams on issue resolution, product safety, design reviews, and readiness milestones. Some domestic and international travel may be required.

Lead end-to-end LLM inference performance across serving systems, models, GPU hardware, and workloads. Define rigorous benchmarks, diagnose bottlenecks from scheduling through kernels and interconnects, optimize single- and multi-node deployments, and deliver production-ready runtimes and configurations. Collaborate with product and infrastructure teams, evaluate inference technologies, and implement runtime fixes. The role requires strong Python engineering, production experience with serving engines such as vLLM or SGLang, GPU profiling, and knowledge of modern inference optimization techniques.

Leads architecture and systems engineering for vacuum SEMI platforms in semiconductor automation. Responsibilities include cross-functional project leadership, technology integration, customer engagement, technical innovation, mentoring engineers, and presenting to management. Requires advanced expertise in vacuum systems and semiconductor automation design, with international travel potentially expected.

Maintains AWS infrastructure supporting PLM applications for DoD customers. Responsibilities include cloud architecture, Ansible automation, database administration, application installation and patching, security updates, performance tuning, testing, troubleshooting, documentation, and infrastructure scaling. Requires AWS and Security+ certifications, enterprise cloud experience, Linux and Windows administration, database expertise, an active or obtainable U.S. national security clearance, and potential travel to customer sites.

Lead systems engineering for advanced audio platforms across embedded, cloud, mobile, and AI/ML domains. Define architecture and requirements, perform trade studies and risk analysis, ensure traceability and verification, drive platform reuse, influence hardware/software decisions, and partner cross-functionally to deliver consumer and automotive audio products from concept through launch.

Leads systems engineering for complex spaceflight electronics, including requirements development, systems analysis, technical baseline management, verification, validation, and design reviews. Collaborates across mechanical, electrical, software, and firmware disciplines; supports program execution, customer interactions, new product development, and proposals. Requires advanced technical judgment and experience delivering aerospace hardware from concept through qualification, production, and customer delivery.

Build and operate Airbnb’s content management systems, including authoring tools, workflows, integrations, analytics, auditing, and AI-assisted features. Own and extend the Contentstack headless CMS using React, TypeScript, and Node.js. Lead complex projects across multiple workstreams, design scalable and fault-tolerant systems, improve reliability and security, mentor engineers, document technical decisions, and collaborate with product, engineering, and content teams.

Lead design and implementation of data architecture and scalable storage solutions, drive AI/GenAI thought leadership, oversee data governance and security, translate business requirements into technical plans, implement FastAPI endpoints, enhance LLMs through prompt engineering, and manage cross-functional teams to deliver advanced data and AI solutions.

Develop and optimize AI and machine learning algorithms, models, and scalable Python systems. Transform raw data into actionable insights, apply machine learning libraries and NLP techniques, improve data quality, and deliver automation solutions for clients. The role also involves complex data analysis, stakeholder collaboration, client relationship management, and navigating ambiguous business challenges.

Serve as the senior LabVantage LIMS expert for Moderna’s Digital Laboratory Systems organization. Lead continuous improvements, support cross-functional projects, and design integrations with MES, SAP, LIMS, and eQMS. Provide level 2/3 application support, including upgrades, patching, deployments, maintenance, and version control. Help shape the integrated digital laboratory systems strategy, manage risks, support demand planning, and develop business cases for system changes in a GxP and GMP environment.

Lead complex presales engagements for Boomi’s API Management solutions across North America. Design API-first strategies, governance models, security policies, developer portals, and enterprise architectures. Advise executive stakeholders on digital ecosystems and business value, lead proofs of concept and RFI/RFP responses, and demonstrate integration between API Management and iPaaS capabilities. The role requires deep expertise in API lifecycle management, gateways, identity and security frameworks, cloud platforms, microservices, service mesh, and event-driven architectures.

Own the design, administration, reliability, security, and roadmap of enterprise identity, endpoint, and SaaS systems. Lead SSO, SCIM, device management, integrations, automation, and AI-assisted workflow projects end to end. Translate ambiguous business needs into scalable solutions, troubleshoot complex incidents, maintain audit-ready controls, evaluate vendors, document systems, mentor engineers, and participate in an after-hours on-call rotation.

Leads complex audio product development from concept through launch, coordinating multidisciplinary internal teams, external partners, and contract manufacturers. Designs and integrates acoustics, DSP, algorithms, firmware, software, hardware, and SoC elements. Drives engineering plans, feasibility assessments, risk resolution, technical deliverables, regulatory compliance, and product-cost targets. Develops and validates audio algorithms and system-level processing architectures using C, MATLAB, Simulink, and real-time DSP techniques.

Lead design, implementation, and maintenance of system architectures across applications, infrastructure, and cloud platforms for federal IT modernization. Provide technical leadership, ensure performance, reliability, and integration, produce documentation, and collaborate with DevOps, security, and stakeholders within Agile teams.

Architect, deploy, and operate highly available multi-cloud infrastructure across AWS and Azure. Manage Kubernetes, Linux systems, databases, caching platforms, CI/CD pipelines, infrastructure as code, observability, security, incident response, and performance optimization. The role also requires automation with Python and Bash, comprehensive documentation, client collaboration, and participation in a 24/7 on-call rotation.

Provides advanced remote IT support, systems administration, infrastructure troubleshooting, and technical escalation across client environments. Administers Microsoft 365, Windows Server, identity systems, Azure, networking, virtualization, endpoint management, and cybersecurity technologies. Mentors junior engineers, resolves complex tickets, maintains documentation and change controls, supports infrastructure initiatives, and evaluates emerging technologies. The role requires remote availability during West Coast Pacific Time business hours and effective communication in a managed services environment.