Top Senior Systems Engineer Jobs in Boston, MA

The Senior Systems Engineer will design, implement, and support IT solutions, manage critical business software, improve processes, and mentor teams.

Lead SAP Basis administration and lifecycle for enterprise SAP landscapes (S/4HANA, RISE, HANA). Provide technical architecture, cloud operations (AWS/Azure/GCP), performance tuning, security, automation, production support, governance, compliance (GxP/CSV), and mentor junior staff to ensure high availability, disaster recovery, and regulatory readiness.

Lead a portfolio of technology projects with a team of developers to create solutions for regulatory needs, collaborating on cloud-based projects while mentoring engineers.

Lead architecture, deployment, security, and governance of multi-cloud (M365, Google Workspace, GCP) environments, including GCC High. Drive migrations, automate workflows with PowerShell/Python/Apps Script/GAM/REST APIs, provide Tier 3 support, and produce documentation and SOPs while ensuring compliance with government security standards.

The Senior Systems Engineer will support sales of enterprise storage, assist in configurations and installations, and collaborate on product requirements and architecture blueprints.

The Senior Systems Engineer will advise DOE customers on architecture design and deployment of VAST's data platform, working with sales teams and managing complex federal accounts.

Responsible for generating business with enterprise customers, managing sales processes, and nurturing customer relationships to expand VAST Data's market presence.

The Senior Systems Engineer will assist customers with system evaluations, configurations, and installations, collaborate with R&D on product specifications, and demonstrate expertise in storage architectures. The role involves creating blueprints for solutions and developing a support organization.

The Senior Systems Engineer will assist customers with evaluations and configurations, demonstrate product expertise, and collaborate on sales strategies and technical documentation.

The Senior Systems Engineer will assist customers with system evaluations, configurations, and installations while promoting and supporting VAST's enterprise storage solutions.

The Senior Systems Engineer will assist customers with evaluations, system installations, and configurations, while collaborating with R&D on product specifications, and demonstrating expertise in storage technologies.

The Senior Systems Engineer I will develop and enhance mobile applications for cardiac health solutions, collaborating with engineers and cross-functional teams to ensure compliance with standards and successful project delivery.

Lead systems engineering for flight autonomy: define subsystem features, requirements, architectures, and test strategies. Manage cross-functional execution, perform V&V, review artifacts with customers and regulators, and collaborate with safety, hardware, and software teams to integrate requirements and interfaces for safety-critical autonomous flight systems.

Lead systems integration for avionics and mission systems from requirements through demonstration on civil-certified and commercial-derivative aircraft. Define CONOPS and architectures, manage requirements and interfaces across hardware/software/safety teams, host design reviews, coordinate suppliers/customers/regulators, and support certification planning, verification, and test in experimental R&D flight test environments.

Senior technical owner of an existing NetSuite ERP: provide Tier 2/3 production support, triage and permanently resolve incidents, build and optimize SuiteScript 2.x and SuiteFlow customizations, maintain integrations (Deposco WMS, Salesforce via Jitterbit), manage SDF sandbox-to-production promotions, monitor performance, ensure release readiness, author runbooks, and operate under ITGC/SOX-adjacent change management with on-call responsibilities.

Designs, deploys, administers, and maintains enterprise SAN storage infrastructure (arrays, SAN switches). Performs provisioning, zoning, masking, replication, performance monitoring, troubleshooting, security remediation, compliance support, vendor coordination, lifecycle management, and provides on-call and onsite support for federal data center operations.

Own and administer Salesforce and NetSuite while designing and deploying production-grade AI-driven automations and agent workflows. Ensure data governance, PHI/HIPAA compliance, release management, and quote-to-cash integrity. Partner cross-functionally to prioritize work, coach teams, document systems, and measure impact of automation on operations and revenue.

Lead implementation and support of an agency-level cybersecurity program. Design and administer RSA Archer solutions, investigate and remediate security incidents, manage SIEM-related troubleshooting, support remote workstation and server management, assess compliance with NIST/FISMA and cloud guidelines, and provide security engineering guidance and documentation.

The Senior GTM Systems Engineer will lead the technical aspects of Salesforce and GTM tooling, focusing on automation, architecture, and scaling the systems as the company grows.

Develop software for instrumentation and machine control, ensuring high performance, reliability, and integration with hardware and software systems.

Lead administration and continuous improvement of the medical device Quality Management System (QMS) and eQMS. Drive CAPA, NCR, audit programs, management review, metrics, system validation, and cross-functional quality initiatives to ensure compliance with FDA QMSR, ISO 13485, MDSAP and other global regulations. Provide SME guidance, perform root-cause analysis, and support regulatory inspections and quality transformations.

Provide advanced, customer-facing technical escalation support for CalixOne and cloud-connected Wi‑Fi premises equipment. Troubleshoot complex networking and cloud issues, use data-driven insights to recommend improvements, create technical documentation, support early adopter customers, collaborate cross-functionally including executive communication, and complete ongoing training to stay current on features and technologies.

Lead systems engineering for space electronics products: develop requirements, manage technical baseline, perform analysis, support design reviews, verification/validation, propose and support new product development, and collaborate across mechanical, electrical, software, and firmware teams.

Leads technical pre-sales activities for cyber resilience and disaster recovery solutions. Partners with sales teams, account managers, and channel partners to understand customer needs, design architectures, conduct evaluations and proof-of-concepts, configure systems, respond to RFPs, and deliver technical presentations. Builds customer-specific solutions, validates interoperability and performance, positions offerings against competitors, and supports opportunities through technical close and revenue growth.

Lead technical engagement with Global Systems Integrator partners to embed VAST into AI, hybrid cloud, and data infrastructure practices. Build reference architectures, enablement programs, demos, and playbooks; support sales cycles, drive partner-led pipeline, and bring partner feedback into product and engineering.