Top Senior Systems Engineer Jobs in Boston, MA

The Sr. Systems Engineer mentors junior engineers, provides IT support, manages service tickets, maintains documentation, and adheres to change control procedures in a collaborative environment.

The Senior Systems Engineer will ensure system availability, security, and performance for a large-scale global infrastructure at Automattic, addressing system health and facilitating developer efficiency.

Lead design verification for electrophysiology systems (Opal HDX), develop/validate test methods and fixtures, execute DV activities, author test procedures/reports, troubleshoot issues with cross-functional teams to support product development and regulatory submissions.

Design, build, and modernize cloud-native systems to automate Arrowstreet's systematic investment processes. Provide technical leadership, mentor engineers, migrate legacy systems to containerized/serverless platforms, optimize data flows for performance and resiliency, automate testing and deployment, and support production incidents with urgency while collaborating with business and technology stakeholders.

Design, build, and deploy scalable laboratory automation workflows and high-throughput workcells. Collaborate with scientists, hardware, controls, and software teams to translate scientific intent into reliable systems, perform testing, FMEAs, troubleshooting, and optimization, and integrate machine vision, sensors, and AI-driven decision logic while ensuring safety, quality, and reproducibility.

Provide systems engineering support across the DoD acquisition lifecycle including requirements, architecture, system modeling, test & evaluation, sustainment, ICDs, proposal evaluation, and technical documentation to deliver and sustain electronic and radar/ATCALS systems for the USAF.

Design, build, and maintain tools and services for Active Directory and cloud identity platforms. Implement security policies and access controls, collaborate on Azure and Google Workspace deployments, automate integrations via APIs and CI/CD, maintain runbooks, participate in on-call rotation, and support AWS infrastructure for production systems.

Lead design, implementation, and maintenance of system architectures across applications, infrastructure, and cloud platforms for federal IT modernization. Provide technical leadership, ensure performance, reliability, and integration, produce documentation, and collaborate with DevOps, security, and stakeholders within Agile teams.

Deploy, upgrade, and maintain High-Speed Data infrastructure supporting DNS, DHCP, DOCSIS provisioning and related platforms. Perform Linux (CentOS/RHEL) administration, scripting/automation (Python, Bash, Ansible, Docker), vendor management, troubleshooting, LLD documentation, project work, training, and on-call support to ensure availability and security of HSD services.

Lead the engineering architecture for an AI-driven product, focusing on system design, collaborating with AI agents, and ensuring quality and scalability in large-scale SaaS environments.

Design and implement production-quality system software, tools, and frameworks for enterprise storage systems. Develop and run realistic validation and analysis solutions, debug cross-layer issues (application, OS, driver, hardware), collaborate with firmware/hardware teams, drive technical design, mentor engineers, and evolve internal tooling with AI integrations.

Lead design and analysis of megawatt-scale electrical power and control systems for the Joule Hive™ thermal battery. Develop electrical simulation methodologies, manage contractors, perform site-specific studies, support installation/commissioning, and hire/mentor junior engineers while collaborating across design teams.

Lead and execute design transfers from development through manufacturing and post-launch. Define system-level I&T requirements, develop test plans, identify and mitigate I&T and manufacturing risks, document best practices, and coordinate cross-functional multi-site teams. Support program planning, schedule/cost control, and customer/government interactions; travel occasionally.

As a Senior Systems Engineer II, you will lead stakeholder discussions, manage system requirements, support software services for cardiac health, and conduct compliance assessments while collaborating with cross-functional teams.

Serve as Tier 3 escalation for an MSP-managed, security-focused practice supporting life sciences clients. Design Microsoft-centric secure architectures (Azure, Microsoft 365, identity, endpoints), lead migrations/onboarding, mentor engineers, own root-cause analysis, implement security controls and compliance alignment, and build automation and AI-assisted tooling (PowerShell, Claude) to reduce manual work.

Lead and sustain HPC system operations for NOAA NWS, managing schedulers and system software, troubleshooting multi-node environments, improving performance and throughput, using Linux administration, PBS Pro/Slurm, scripting (Bash/Python/Perl), MPI, and participating in 24/7 on-call rotations with occasional travel for collaboration and training.

Key responsibilities include troubleshooting complex technical issues, mentoring junior team members, streamlining processes, and ensuring quality assurance in IT support.

Define and flow down engineering requirements from high-level designs, document and manage requirement changes, maintain system architecture and interfaces, identify tools/process improvements, and coach teams on systems engineering practices for complex hardware/firmware/software products.

The Systems Engineer III/Senior will manage virtualization environments, focusing on hypervisor platforms, system architecture, automation, and software integration in a secure DoD setting.

The role involves leading systems engineering for product development in defense and aerospace systems, managing requirements, and collaborating with teams on complex engineering solutions.

Provide technical leadership in manufacturing complex infrared imaging systems, ensure product transition from development to production, and improve processes continuously.

Lead and support design, deployment, administration, and Tier-2/3 support of AWS and hybrid-cloud systems. Maintain Linux/Windows servers, IP networking, automate operations with IaC/configuration management, produce documentation, and troubleshoot mission-critical infrastructure in a secured, fast-paced environment.

Lead mission readiness and performance across the Mission Foundry lifecycle: define V&V campaigns, streamline AI&T workflows, analyze on-orbit telemetry, improve autonomy and fault management, feed performance data into design iterations, and support internal tooling roadmaps to scale spacecraft production and operations.

The Senior Systems Engineer I will develop and enhance mobile applications for cardiac health solutions, collaborating with engineers and cross-functional teams to ensure compliance with standards and successful project delivery.

Design, implement, and scale event-driven, distributed backend systems in Python on AWS to process and enrich large-scale document and media datasets. Lead technical projects, mentor engineers, integrate ML/LLM components, optimize performance, maintain observability, and collaborate with Data Science, ML Engineering, and Product to deliver reliable high-throughput content processing services.