Top Senior Systems Engineer Jobs in Boston, MA

Reposted 5 Hours AgoSaved
Remote
Boston, MA
127K-165K Annually
Senior level
127K-165K Annually
Senior level
Healthtech
As a Senior Systems Engineer II, you will lead stakeholder discussions, manage system requirements, support software services for cardiac health, and conduct compliance assessments while collaborating with cross-functional teams.
Top Skills: C#C/C++DoorsJamaJavaPolarionPythonSplunkSysmlUml
YesterdaySaved
Remote
Boston, MA
Senior level
Senior level
Professional Services • Financial Services
Serve as Tier 3 escalation for an MSP-managed, security-focused practice supporting life sciences clients. Design Microsoft-centric secure architectures (Azure, Microsoft 365, identity, endpoints), lead migrations/onboarding, mentor engineers, own root-cause analysis, implement security controls and compliance alignment, and build automation and AI-assisted tooling (PowerShell, Claude) to reduce manual work.
Top Skills: Active DirectoryAzureAzure AdBackup And Disaster RecoveryClaudeConnectwiseDlpEndpoint ProtectionEntra IdExchange OnlineFirewallsIdentity GovernanceIntuneMfa/Conditional AccessMicrosoft 365NinjaoneOnedrivePowershellPythonSharepointSwitchingVirtualizationVpnWindows Server
136K-184K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Lead and sustain HPC system operations for NOAA NWS, managing schedulers and system software, troubleshooting multi-node environments, improving performance and throughput, using Linux administration, PBS Pro/Slurm, scripting (Bash/Python/Perl), MPI, and participating in 24/7 on-call rotations with occasional travel for collaboration and training.
Top Skills: BashHigh Performance Computing (Hpc)MpiPbs ProPerlPythonRed Hat Enterprise Linux (Rhel)Rocky LinuxSlesSlurm
Reposted YesterdaySaved
Remote
Boston, MA
Mid level
Mid level
HR Tech • Professional Services • Software • Consulting
Key responsibilities include troubleshooting complex technical issues, mentoring junior team members, streamlining processes, and ensuring quality assurance in IT support.
Top Skills: Apple Certified Support ProfessionalApple ProductsCisco Certified Network AssociateComptia A+CongaDomoGoogle ApplicationsSalesforce
Reposted YesterdaySaved
Remote
Boston, MA
Senior level
Senior level
Artificial Intelligence • Cloud • Hardware • Machine Learning • Quantum Computing
Define and flow down engineering requirements from high-level designs, document and manage requirement changes, maintain system architecture and interfaces, identify tools/process improvements, and coach teams on systems engineering practices for complex hardware/firmware/software products.
Top Skills: Model-Based Systems Engineering (Mbse)Requirements Management Software
Reposted 2 Days AgoSaved
Remote
Boston, MA
156K-235K Annually
Senior level
156K-235K Annually
Senior level
Aerospace • Logistics • Security • Software • Cybersecurity
Lead and support design, deployment, administration, and Tier-2/3 support of AWS and hybrid-cloud systems. Maintain Linux/Windows servers, IP networking, automate operations with IaC/configuration management, produce documentation, and troubleshoot mission-critical infrastructure in a secured, fast-paced environment.
Top Skills: AnsibleAWSAzureBashConfiguration ManagementDockerGCPHybrid CloudInfrastructure As CodeIp NetworkingKubernetesLinuxMysql RdsOspfPodmanPostgresPowershellPuppetPythonSubnettingVlansVpnsWindows
13 Days AgoSaved
In-Office
Boston, MA
115K-173K Annually
Senior level
115K-173K Annually
Senior level
Semiconductor • Manufacturing
Lead and structure design programs for lithography product lines, develop system and subsystem requirements, coordinate HW and SW teams, define test/success criteria, and shepherd products from concept through release and introduction to manufacturing.
Top Skills: 3D MetrologyDynamic Systems ControlElectro-Mechanical SystemsEmbedded MetrologyLatency DiagnosisLithographyMotion ControlOptical EngineeringPrecision AlignmentServo MotorsStepper MotorsTiming Diagrams
10 Days AgoSaved
Easy Apply
Remote or Hybrid
Boston, MA
Easy Apply
Senior level
Senior level
Artificial Intelligence • Big Data • Cloud • Security • Software • Cybersecurity • Infrastructure as a Service (IaaS)
Lead development and integration of Salesforce-centered GTM systems: build Apex/LWC solutions, design event-driven integrations, optimize data flows to Snowflake, manage CI/CD with Gearset/Git, write SQL for reporting and data quality, troubleshoot production, and mentor developers while advancing AI-enabled, composable CRM automation.
Top Skills: ApexCpqExperience CloudGearsetGitLightning Web ComponentsPlatform EventsRest ApisSales CloudSalesforceSalesforce ApiSalesforce FlowService CloudSQLWebhooks
Reposted 4 Days AgoSaved
Remote
Boston, MA
98K-122K Annually
Senior level
98K-122K Annually
Senior level
Fintech • Financial Services
The Senior Systems Engineer will manage Azure virtual desktop infrastructure, ensuring security and performance while collaborating with cross-functional teams and supporting end users.
Top Skills: Azure AdAzure Virtual DesktopEnterprise StorageExchange OnlineFslogixMicrosoft Active DirectoryMicrosoft Server TechnologiesO365Tcp/Ip NetworkingWindows Based Applications
Reposted 14 Days AgoSaved
Hybrid
Boston, MA
170K-190K Annually
Senior level
170K-190K Annually
Senior level
Aerospace
The Senior Systems Engineer will evaluate and improve systems engineering processes and conduct system level tests to ensure performance meets specifications, providing technical support and training throughout program lifecycle.
Top Skills: Computer ScienceElectrical EngineeringSystems Engineering
Reposted 14 Days AgoSaved
In-Office
Boston, MA
Senior level
Senior level
Automation • Manufacturing
The Senior Systems Engineer will design, implement, and support IT solutions, manage critical business software, improve processes, and mentor teams.
Top Skills: Cad SystemsDefender For EndpointDhcpDnsEntra IdIntuneMicrosoft 365AzureSharepointTeamsWindows Os
Reposted 5 Days AgoSaved
Remote
Boston, MA
115K-149K Annually
Senior level
115K-149K Annually
Senior level
Healthtech
The Senior Systems Engineer I will develop and enhance mobile applications for cardiac health solutions, collaborating with engineers and cross-functional teams to ensure compliance with standards and successful project delivery.
Top Skills: BleCellularDoorsIot HardwareJamaMobile ApplicationsPolarionWi-Fi
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15 Days AgoSaved
In-Office or Remote
Boston, MA
113K-203K Annually
Senior level
113K-203K Annually
Senior level
Cloud • Security • Software • Cybersecurity
Lead architecture, deployment, security, and governance of multi-cloud (M365, Google Workspace, GCP) environments, including GCC High. Drive migrations, automate workflows with PowerShell/Python/Apps Script/GAM/REST APIs, provide Tier 3 support, and produce documentation and SOPs while ensuring compliance with government security standards.
Top Skills: CmmcCompute EngineEntra IdExchange OnlineFedrampGamGcc HighGCPGoogle Admin ConsoleGoogle Apps ScriptGoogle GeminiGoogle WorkspaceIamIl5IntuneMicrosoft 365PowershellPythonRag/McpRest ApisSharepoint OnlineTeamsVpc
Reposted 20 Days AgoSaved
Hybrid
Boston, MA
209K-286K Annually
Senior level
209K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead a portfolio of technology projects with a team of developers to create solutions for regulatory needs, collaborating on cloud-based projects while mentoring engineers.
Top Skills: Amazon SagemakerAWSCSSDatabricksDockerGoHTMLJavaJavaScriptKubernetesLuaMcpPythonSQLTypescript
16 Days AgoSaved
Hybrid
Boston, MA
Senior level
Senior level
Aerospace • Hardware • Software
Lead systems engineering for flight autonomy: define subsystem features, requirements, architectures, and test strategies. Manage cross-functional execution, perform V&V, review artifacts with customers and regulators, and collaborate with safety, hardware, and software teams to integrate requirements and interfaces for safety-critical autonomous flight systems.
Top Skills: Arp4754ACameoIadsJamaMbseRtca Do-178B/CSimulink
Reposted 6 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Artificial Intelligence • Software
The Senior Systems Engineer will support sales of enterprise storage, assist in configurations and installations, and collaborate on product requirements and architecture blueprints.
Top Skills: Enterprise SecurityEnterprise StorageHigh-Performance NetworkingVirtualization
Reposted 6 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Artificial Intelligence • Software
The Senior Systems Engineer will advise DOE customers on architecture design and deployment of VAST's data platform, working with sales teams and managing complex federal accounts.
Top Skills: Ai/MlData PlatformsEnterprise SecurityEnterprise StorageHigh-Performance NetworkingHpcVirtualization
Reposted 6 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Artificial Intelligence • Software
Responsible for generating business with enterprise customers, managing sales processes, and nurturing customer relationships to expand VAST Data's market presence.
Top Skills: Ai InfrastructureData ManagementEnterprise SecurityEnterprise StorageHigh-Performance NetworkingVirtualizationWeb Frameworks
Reposted 6 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Artificial Intelligence • Software
The Senior Systems Engineer will assist customers with system evaluations, configurations, and installations, collaborate with R&D on product specifications, and demonstrate expertise in storage architectures. The role involves creating blueprints for solutions and developing a support organization.
Top Skills: Enterprise SecurityHigh-Performance NetworkingVirtualization
Reposted 6 Days AgoSaved
Remote
Boston, MA
5-5 Annually
Senior level
5-5 Annually
Senior level
Artificial Intelligence • Software
The Senior Systems Engineer will assist customers with evaluations and configurations, demonstrate product expertise, and collaborate on sales strategies and technical documentation.
Top Skills: Enterprise SecurityEnterprise StorageHigh-Performance NetworkingVirtualization
Reposted 6 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Artificial Intelligence • Software
The Senior Systems Engineer will assist customers with system evaluations, configurations, and installations while promoting and supporting VAST's enterprise storage solutions.
Top Skills: Enterprise SecurityHigh-Performance NetworkingVirtualization
Reposted 6 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Artificial Intelligence • Software
The Senior Systems Engineer will assist customers with evaluations, system installations, and configurations, while collaborating with R&D on product specifications, and demonstrating expertise in storage technologies.
Top Skills: DasDistributed Storage ArchitecturesEnterprise SecurityFile SystemsHigh-Performance NetworkingNasSanStorage ProductsSystems EngineeringVirtualization
7 Days AgoSaved
Remote
Boston, MA
89K-210K Annually
Senior level
89K-210K Annually
Senior level
Information Technology • Utilities • Big Data Analytics
Designs, deploys, administers, and maintains enterprise SAN storage infrastructure (arrays, SAN switches). Performs provisioning, zoning, masking, replication, performance monitoring, troubleshooting, security remediation, compliance support, vendor coordination, lifecycle management, and provides on-call and onsite support for federal data center operations.
Top Skills: BrocadeDell PowermaxHpe 3ParMaskingNetappOlvmOracle LinuxPowershellPythonReplicationSanStorage ArraysUnix ShellVMwareWindowsZoning
Reposted 16 Days AgoSaved
In-Office
Boston, MA
115K-173K Annually
Senior level
115K-173K Annually
Senior level
Semiconductor • Manufacturing
Lead system-level definition and integration of the Common EFEM platform, collaborating across various engineering disciplines to define requirements, architecture, and validate performance.
Top Skills: Factory AutomationMatlabPrecision MotionPythonRoboticsSemi Standards
22 Days AgoSaved
In-Office or Remote
Boston, MA
110K-170K Annually
Senior level
110K-170K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Lead systems engineering for Hivemind-based autonomy products: define and manage requirements, develop system architectures and trade studies, coordinate hardware/software interfaces, support integration/verification/validation and testing, and identify and mitigate technical risks across the system lifecycle.
Top Skills: C++Cameo ApiHivemind Autonomy SoftwareMbsePythonVelocity Template Language (Vtl)
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