Top Principal Software Engineer Jobs in Boston, MA

Lead the implementation of advanced NLP solutions, develop AI/ML applications, oversee model training and evaluation, and collaborate across teams.

Lead the design and implementation of AI-driven solutions, establish architectural direction, mentor engineers, and optimize AI systems. Drive technical alignment with product management.

As a Principal Software Engineer, you will architect WEX's Data-as-a-Service platform, set standards, guide strategy, and mentor teams while driving innovation with modern technologies.

Analyze and optimize system performance, develop solutions, extend metrics collection, build performance tools, and provide training across teams.

Lead technical vision and architecture for a cloud-native, event-driven health platform. Guide teams from prototype to production, ensure reliability, security, performance, and strong engineering practices (testing, observability, CI/CD), mentor senior engineers, and collaborate with product and architecture stakeholders to drive platform roadmaps and execution.

Lead design, architecture, and hands-on implementation of scalable healthcare SaaS systems. Drive interoperability (HL7, FHIR, EDI), mentor engineers, liaise with stakeholders, manage technical risk, and ensure quality, performance, security, and innovation.

Founding engineer responsible for architecting and building core product systems, writing scalable Python backend code, designing and maintaining AI/ML infrastructure, instituting best development practices (testing, CI/CD), collaborating on product roadmap, and mentoring future engineers.

Design, build, and improve Elasticsearch distributed-systems components for scalable, concurrent, and consistent indexing. Maintain cluster coordination for performance and resilience, push system scale limits, investigate performance and concurrency issues, support operations/support engineers, and lead projects involving multiple engineers from design through delivery.

Lead AI engineering initiatives, develop AI systems, integrate LLMs, mentor teams, and collaborate on business requirements within agile frameworks.

The Principal Software Engineer will develop imaging application software, create architecture, refine software processes, and manage technical teams, focusing on signal processing and software documentation.

The Principal Software Engineer leads technical vision and strategy for the division, mentors staff, and drives architectural standards across multiple business units.

As a Principal Software Engineer, you'll lead projects in Linux virtualization, design complex features, and collaborate in an Agile Scrum team, while ensuring software quality and customer advocacy.

The Principal Software Engineer at Snout will define architectural direction, build features across the stack, and enhance team effectiveness, ensuring quality and performance.

Lead reliability, availability, and resiliency strategies for large-scale systems, drive operational excellence, and provide technical mentorship across engineering teams.

The Principal Software Engineer will lead the design and development of scalable AI-native cybersecurity systems, drive technical initiatives, and mentor engineers while collaborating closely with cross-functional teams.

As a Principal Software Engineer, you'll develop software systems for NVIDIA's rack-scale infrastructure, defining software architecture, collaborating across teams, mentoring engineers, and ensuring high-quality technical decisions in complex environments.

The Principal Software Engineer will shape the Commerce Hub's technical future, build scalable systems, lead architectural changes, mentor engineers, and influence product strategy.

Lead compiler development for Xcelium, creating advanced language extensions, optimizing performance, and innovating for complex AI chip designs.

The Principal Engineer will lead the Test Platform Services team, focusing on building validation systems, ensuring reliability and scalability, and fostering team growth.

The Principal Software Engineer provides technical leadership for enterprise applications focusing on ERP and core systems, resolving complex issues, and enhancing solutions while ensuring best practices in full-stack development.

Lead technical direction for major full‑stack product areas, architect scalable systems across frontend, backend, and data, build AI-powered features (LLMs/embeddings), drive large cross-team initiatives, establish engineering standards (reliability, testing, observability), remove systemic risks, and mentor engineers while partnering with product and design to deliver customer-focused outcomes.

Lead design and implementation of large-scale search and retrieval systems, improve relevance using lexical and vector techniques, build scalable data workflows and microservices (Spark, Airflow), write testable code in Python/Java/Scala, diagnose distributed system issues, mentor engineers, and collaborate across product and platform teams to deliver production search infrastructure.

Lead a full-stack product team to build secure financial and card issuance SaaS solutions while ensuring system reliability and compliance in a regulated environment.

ABCorp is looking for a Principal Software Engineer to lead the technical direction of their Client Experience Platform, overseeing frontend, backend, and data architecture while mentoring engineers and collaborating with Product and UX teams.

Lead the design and development of web and mobile applications, mentor engineers, collaborate with teams, and manage software architecture while advocating for best practices in performance and accessibility.