Top Chief Of Staff Jobs in Boston, MA

9 Days AgoSaved
In-Office
Boston, MA
220K-295K Annually
Senior level
220K-295K Annually
Senior level
Beauty • Robotics • Design • Appliances • Manufacturing
Serve as the CPO's strategic operating partner for a ~480-person global Product Development org. Own executive rhythm, synthesize decision-ready materials, resolve cross-functional friction, and build reporting and operating cadences. Lead geo-expansion strategy across 32 markets, design and operationalize a cross-category loyalty program, and deploy AI-enhanced portfolio intelligence. Partner on org design, headcount planning, and high-priority cross-functional initiatives. Champion AI and automation adoption to accelerate decision-making and portfolio visibility.
Reposted 9 Days AgoSaved
Easy Apply
Hybrid
Boston, MA
Easy Apply
Mid level
Mid level
Fitness • Hardware • Healthtech • Sports • Wearables
The Deputy Chief of Staff will support the CEO by managing high-priority initiatives, preparing briefing materials, facilitating team communication, and executing events, requiring strong organizational and communication skills.
Top Skills: Ai Tools
3 Days AgoSaved
Easy Apply
Remote or Hybrid
Boston, MA
Easy Apply
216K-356K Annually
Expert/Leader
216K-356K Annually
Expert/Leader
Marketing Tech • Social Media • Software • Analytics • Business Intelligence
Partner with the CPO and CTO to run R&D operations: lead operating cadence, OKR alignment, reporting/dashboards, budget governance, and cross-functional strategic initiatives. Triage escalations, drive org design and AI-operating-model projects, and draft executive and board communications to enable prioritized, data-driven R&D decision making.
4 Days AgoSaved
In-Office or Remote
Boston, MA
175K-250K Annually
Senior level
175K-250K Annually
Senior level
Artificial Intelligence • Blockchain • Professional Services • Security • Consulting • Cybersecurity • Defense
Serve as the CEO's right-hand, managing their time and communications, driving strategic planning, owning cross-functional projects, building accountability systems, drafting executive materials, and executing organizational priorities to ensure follow-through and operational efficiency.
Top Skills: Ai ToolsAutomationEosSlack
10 Days AgoSaved
Remote or Hybrid
Boston, MA
156K-210K Annually
Expert/Leader
156K-210K Annually
Expert/Leader
Edtech • Information Technology • Software
Partner with the CPO to translate strategy into operating action, drive cross-functional execution, manage high-priority special projects, run product management rhythms, surface risks and dependencies, improve meeting and escalation discipline, and represent the CPO in internal forums to ensure alignment and delivery during reorganization.
Reposted 13 Days AgoSaved
Remote
Boston, MA
160K-180K Annually
Mid level
160K-180K Annually
Mid level
Insurance • Legal Tech • Social Impact
The Chief of Staff will lead strategic initiatives for new business lines at Atticus, focusing on client acquisition and operational strategy while collaborating with various leaders.
Reposted YesterdaySaved
In-Office
Boston, MA
Senior level
Senior level
AdTech
The Chief of Staff to the Founder will translate the founder's vision into executable plans, lead AI projects, drive sales initiatives, and build systems for organizational efficiency, while managing client delivery and talent acquisition.
Top Skills: AIAsanaGoogle WorkspaceNotionSlack
4 Days AgoSaved
Hybrid
Boston, MA
170K-200K Annually
Senior level
170K-200K Annually
Senior level
Artificial Intelligence • Cloud • Gaming • Machine Learning • Software • Virtual Reality • Cybersecurity
Serve as a strategic partner to the CEO and CTO, drive cross-functional initiatives, improve organizational effectiveness, lead people operations, and coordinate major company priorities to enable scalable growth.
4 Days AgoSaved
In-Office
Boston, MA
250K-285K Annually
Expert/Leader
250K-285K Annually
Expert/Leader
Software
Senior Chief of Staff partnering with the CTO to represent him in executive forums, run operating rhythms, lead strategic initiatives, synchronize engineering/product/data strategy (especially AI), produce C‑suite materials, and ensure follow-through across a global organization. Requires judgement to act with CTO authority, build senior relationships, and drive high‑impact outcomes.
6 Days AgoSaved
In-Office
Boston, MA
186K-345K Annually
Expert/Leader
186K-345K Annually
Expert/Leader
Biotech • Pharmaceutical
Senior strategic partner to the CSO & Site Head driving portfolio vision, program execution, governance, cross-functional integration, change management, and communications. Chairs portfolio review, leads strategic working groups, manages resource allocation, risk mitigation, publication strategy, and stakeholder alignment across Mariana and Novartis.
Reposted 2 Days AgoSaved
Easy Apply
Remote or Hybrid
Boston, MA
Easy Apply
167K-372K Annually
Senior level
167K-372K Annually
Senior level
Fintech • Information Technology • Payments • Productivity • Software • Travel • Automation
The Chief of Staff will advise the SVP of Global Operations, manage operational initiatives, coordinate meetings, oversee goal-setting, and drive strategic projects.
Reposted 8 Days AgoSaved
In-Office
Boston, MA
182K-275K Annually
Expert/Leader
182K-275K Annually
Expert/Leader
Biotech
The Chief of Staff will support the EVP, North America by driving strategic initiatives, enhancing operational efficiency, and supporting organizational goals, requiring strong leadership and project management skills.
Top Skills: Co PilotExcelPowerPointSmartsheet
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Reposted 9 Days AgoSaved
In-Office
Boston, MA
185K-278K Annually
Expert/Leader
185K-278K Annually
Expert/Leader
Biotech • Pharmaceutical
The Chief of Staff leads strategic and operational project management, communicates effectively with stakeholders, and supports research initiatives in a biotech setting.
Top Skills: Business Case DevelopmentPortfolio ManagementProject ManagementStrategic Planning
Reposted 4 Hours AgoSaved
Remote
Boston, MA
Senior level
Senior level
AdTech
Lead operational rhythms and client delivery, focusing on AI solutions. Collaborate with executives and manage multi-stakeholder projects for positive outcomes.
Top Skills: Ai SolutionsAsanaGoogle WorkspaceLlm-Enabled Use CasesNotionSlack
YesterdaySaved
Remote or Hybrid
Boston, MA
Senior level
Senior level
Artificial Intelligence • Fintech • Software • Financial Services
Lead and run multi-country business operations: build operational infrastructure, set up offices and entities, implement payroll, manage vendors, support recruiting operations, plan events, track initiatives, and improve processes to ensure scalable execution.
2 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Big Data • Healthtech • Software • Biotech
Partner with the CEO/COO to translate strategy into execution, build AI-enabled operating systems, drive cross-functional programs, run OKRs and planning cadences, scale vendor/procurement, and lead high-priority projects end-to-end.
Top Skills: Ai AgentsAi ToolsOkr FrameworksSaas/Ai ToolsWorkflow Automation
Reposted 2 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Professional Services
The Chief of Staff supports the Chairman by driving strategic initiatives, managing projects, and optimizing decision-making processes while ensuring operational efficiency across ventures.
Top Skills: Ai WorkflowsAutomation SystemsProductivity PlatformsProject Management Tools
Reposted 2 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Healthtech
The Chief of Staff will work closely with the CEO and leadership team to drive company-wide execution, oversee strategic initiatives, improve processes across teams, and lead critical projects to accelerate growth and patient impact.
Top Skills: Data AnalysisKpi DashboardsModelingProgram Management Tools
3 Days AgoSaved
Remote
Boston, MA
130K-160K Annually
Mid level
130K-160K Annually
Mid level
Digital Media • News + Entertainment
Partner with the CEO and leadership to drive strategic execution, run leadership rhythms, translate goals into OKRs and roadmaps, lead cross-functional initiatives, improve studio workflows, and ensure alignment across Creative, Production, and Business teams.
Reposted 12 Days AgoSaved
In-Office
Boston, MA
Senior level
Senior level
Artificial Intelligence • Biotech
The Chief of Staff will support the CEO by increasing decision velocity and execution quality, managing initiatives, and handling executive communication and fundraising.
Top Skills: AIBiologyFundraising
3 Days AgoSaved
Remote
Boston, MA
Senior level
Senior level
Artificial Intelligence • Marketing Tech • Productivity • Generative AI
Strategic Chief of Staff who designs systems, anticipates problems, researches and decides best practices, manages the EA, builds recruiting/operations processes, and multiplies founder leverage. High-energy, AI-native partner who executes strategically and delegates operational tasks.
Top Skills: Ai AgentsAi WorkflowsAutomationsChatgptClaudeClaude CodeNotionPoppy
3 Days AgoSaved
Remote
Boston, MA
166K-207K Annually
Senior level
166K-207K Annually
Senior level
Artificial Intelligence • Information Technology • Consulting
Operate as Chief of Staff/Strategic Program Manager driving Nebius' top initiatives. Align Product, Engineering, Sales, Marketing and leadership on execution plans, build operating systems (dashboards, QBRs, reviews), remove blockers, translate complex technical and business issues into executive-ready recommendations, and ensure teams deliver on product launches, GTM programs, partnerships, and organizational priorities.
13 Days AgoSaved
In-Office or Remote
Boston, MA
124K-223K Annually
Senior level
124K-223K Annually
Senior level
Big Data • Cloud • Digital Media • Machine Learning • Mobile • Software • Industrial
The Chief of Staff, Fusion Sales drives operational excellence and organizational alignment within the Fusion Sales team, providing strategic partnership and executing key business initiatives across the global organization.
Top Skills: Ai-Powered ToolsBusiness Analytics SoftwareOperational Efficiency
Reposted 5 Days AgoSaved
In-Office or Remote
Boston, MA
Mid level
Mid level
Artificial Intelligence • Big Data • Information Technology • Software
The BizOps Lead will advise the CEO, manage strategic initiatives, coordinate programs, prepare communications for stakeholders, and lead special projects.
Top Skills: AirtableAsanaGoogle WorkspaceNotionSlack
6 Days AgoSaved
Remote
Boston, MA
60K-170K Annually
Mid level
60K-170K Annually
Mid level
Edtech • Professional Services • Sales • Consulting
Provide high-trust executive operations support to the CEO: own and optimize calendar, run the follow-up/action engine, manage company project systems, lead hiring operations, oversee content ops (delivery only), analyze monthly P&L and payroll, and execute personal/local projects. Build systems, hold leaders accountable, and scale into a Chief of Staff role over 3–18 months.
Top Skills: AsanaCalendlyChatgptGoogle WorkspaceImessageLoomNotionSlackTrelloWhatsappZoom
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