Top Chief Of Staff Jobs in Boston, MA

Senior Chief of Staff partnering with the CTO to represent him in executive forums, run operating rhythms, lead strategic initiatives, synchronize engineering/product/data strategy (especially AI), produce C‑suite materials, and ensure follow-through across a global organization. Requires judgement to act with CTO authority, build senior relationships, and drive high‑impact outcomes.

Serve as strategic advisor and operational leader to the Chief Commercial Officer, translating CCO priorities into actionable commercial roadmaps, driving revenue acceleration, overseeing partnerships and GTM alignment, establishing governance rhythms, preparing executive materials, and leading analytics and performance management to improve forecasting, pipeline health, and commercial outcomes.

Partner with the CPO and CTO to run R&D operations: lead operating cadence, OKR alignment, reporting/dashboards, budget governance, and cross-functional strategic initiatives. Triage escalations, drive org design and AI-operating-model projects, and draft executive and board communications to enable prioritized, data-driven R&D decision making.

Serve as the CEO's right-hand, managing their time and communications, driving strategic planning, owning cross-functional projects, building accountability systems, drafting executive materials, and executing organizational priorities to ensure follow-through and operational efficiency.

The Chief of Staff will lead strategic initiatives for new business lines at Atticus, focusing on client acquisition and operational strategy while collaborating with various leaders.

Partner with the CEO to drive strategy, execution, and external engagement. Run executive operating cadence, prepare board and investor materials, oversee cross-functional initiatives, translate technical science/AI work for leadership, and ensure decisions are driven to closure. Act as a connector across the leadership team while building operational systems and standards across chiefs of staff and EAs.

Serve as strategic partner and operational lead to the VP of Global Regulatory Affairs. Drive governance, planning, and cross-functional coordination to advance filing readiness and approvals. Lead business planning, performance management, organizational effectiveness, change initiatives, and executive communications. Represent the VP in forums, create executive materials, and ensure decisions have owners, timelines, and follow-through.

Partner with the CFO to prioritize and advance high-impact finance, people, operations, and strategy work. Shape operating cadence, prepare executive materials, track CFO-owned projects to closure, coordinate cross-functional stakeholders, resolve stalled work, and draft decision notes and executive communications to maintain momentum and clarity across the CFO portfolio.

The Chief of Staff to the Founder will translate the founder's vision into executable plans, lead AI projects, drive sales initiatives, and build systems for organizational efficiency, while managing client delivery and talent acquisition.

Act as the founders' right hand to operationalize AI: prototype internal AI workflows, turn experiments into company-wide programs, run executive cadence and OKRs, unblock cross-functional projects, prepare strategic briefs, enforce responsible AI guardrails, and drive exit-readiness and organizational health.

Serve as VP/GM's strategic partner to drive operational execution, program management, and cross-functional alignment for athenaFlex. Own business rhythms, lead special projects, track metrics, manage a small operations team, coordinate leadership meetings, and enable strategic planning and decision-making across Product, Engineering, Sales, Finance, HR, and Marketing.

Work directly with the CEO and CFO to translate executive priorities into execution: lead strategic initiatives, run executive operating rhythms (meetings, OKRs), synthesize decision-ready materials, coordinate cross-functional workstreams, support finance with analysis and board/investor materials, and represent leadership in confidential matters.

Act as the CTO's right hand for R&D and Technology, owning program management, roadmaps, milestone tracking, dependency management across chemistry and engineering workstreams, translating between technical teams and business stakeholders, preparing executive/investor materials, and building operating cadence and decision processes without adding bureaucracy.

The Chief of Staff / Integrator will manage operations for two eCommerce brands, driving execution, improving workflows, and building operational systems to support growth.

Lead operational rhythms and client delivery, focusing on AI solutions. Collaborate with executives and manage multi-stakeholder projects for positive outcomes.

Operate as Chief of Staff/Strategic Program Manager driving Nebius' top initiatives. Align Product, Engineering, Sales, Marketing and leadership on execution plans, build operating systems (dashboards, QBRs, reviews), remove blockers, translate complex technical and business issues into executive-ready recommendations, and ensure teams deliver on product launches, GTM programs, partnerships, and organizational priorities.

Partner with the founder and leadership team to build and run the company operating system: filter founder intake, convert ideas into decisions with owners and deadlines, run executive rhythm, close cross-functional work, build ClickUp/SOPs/knowledge systems, and implement AI-driven automations to increase founder leverage and ensure leaders reliably hit commitments.

Serve as strategic partner to senior sales leaders, align priorities, drive cross-functional initiatives, manage KPIs and performance reporting, lead Impact Managers, and scale Employee Benefits sales and client management through transformation and execution discipline.

The Chief of Staff will work closely with the CEO and leadership team to drive company-wide execution, oversee strategic initiatives, improve processes across teams, and lead critical projects to accelerate growth and patient impact.

Partner with the CEO/COO to translate strategy into execution, build AI-enabled operating systems, drive cross-functional programs, run OKRs and planning cadences, scale vendor/procurement, and lead high-priority projects end-to-end.

Partnering with the CEO, lead strategic initiatives and build business operations. Facilitate executive alignment, create KPI frameworks and dashboards, run cross-functional execution, improve communication, and remove operational friction to drive company-wide results.

The Chief of Staff will support the CTO by translating company strategy into operational systems, managing projects, driving alignment, and enhancing leadership within the Tech organization, ensuring effective execution of strategic initiatives.

The Chief of Staff supports the Chairman by driving strategic initiatives, managing projects, and optimizing decision-making processes while ensuring operational efficiency across ventures.

The Chief of Staff, Fusion Sales drives operational excellence and organizational alignment within the Fusion Sales team, providing strategic partnership and executing key business initiatives across the global organization.

Serve as the SVP's right hand for Healthcare Analytics by managing budgets and ROI, running operational rhythms (recruiting, onboarding, meetings), producing executive communications, supporting strategic planning and talent processes, coordinating cross-functionally, and resolving blockers to ensure delivery and alignment.