Jobs at Kymera Therapeutics

Lead Kymera's enterprise AI strategy and roadmap; prototype, build, and deploy AI/LLM solutions; select and govern AI platforms; establish AI governance with InfoSec; manage vendors and external engagements; drive adoption through training; and advise functional leaders to operationalize AI across research, development, regulatory, and G&A.

Lead early commercial strategy for assigned programs, including indication prioritization, market landscapes, forecasting, primary/secondary research, and competitive intelligence. Partner with cross-functional teams to shape target product profiles, evidence-generation priorities, and portfolio decisions. Use AI-enabled tools to accelerate intelligence workflows, attend scientific meetings, and deliver concise executive-ready analyses to inform development and business development opportunities.

Lead HEOR, RWE, and value strategy across Kymera's immunology portfolio. Drive economic modeling, payer engagement, AMCP dossiers, RWE plans, HTA readiness, cross-functional launch preparation, and build a high-performing outcomes and access team.

The role involves leading targeted proteomics research, developing and optimizing assays, and collaborating with project teams to inform drug discovery decisions.

Lead analytics for clinical trial feasibility and enrollment planning by integrating internal and external data, building forecasts and dashboards, monitoring study performance, assessing competitive trial landscape, automating reporting, and delivering executive-level insights to optimize study design and execution across the clinical portfolio.

Lead and grow PBPK/PBBM capabilities to predict human PK and oral bioavailability, support formulation selection and IVIVC, model DDI/food effects and special populations, embed in project teams, liaise with partners/CROs, and prepare regulatory documentation to support IND/NDA submissions and health authority interactions.

Lead strategic sourcing for R&D vendors (CROs, CMOs), manage supplier relationships, negotiate MSAs/SOWs, run RFPs and vendor selection, identify cost savings, track contract status and vendor performance, and improve sourcing processes across the organization.

Manage and maintain Kymera's electronic Quality Management System (Veeva Vault) including document control, training program administration, compliance monitoring, metrics reporting, and inspection-ready records. Support SOP lifecycle, vendor qualification, and continuous improvement to sustain QMS operations during late-stage development and commercialization.

Senior IT leader embedded in Development to define and execute technology strategy for clinical programs. Own Veeva Vault implementations (QMS, eTMF, CTMS), validated systems governance, regulatory submission readiness, vendor relationships, data integrations, and AI-enabled opportunities. Drive requirements gathering, process design, change management, and ensure GxP/21 CFR Part 11 compliance while supporting Phase 3, NDA, and commercialization scale.

Lead global and U.S. pricing, reimbursement, access, and value strategies across Kymera's pipeline. Drive payer engagement, pricing governance, evidence-generation alignment with Clinical/HEOR, launch readiness, and lifecycle access optimization. Influence cross-functional strategy, manage market access risks, and support commercial planning to maximize patient access and product value for immunology indications.

Lead global commercial strategy, brand planning, and launch readiness for KT-621. Define product vision, positioning, target segments, and value proposition. Drive launch execution, cross-functional alignment, evidence generation, market assessments, and lifecycle expansion across immunology indications. Partner with Clinical Development, Medical Affairs, Market Access, Regulatory, Finance, and Analytics to support successful US and global commercialization.

Lead Kymera's business development strategy by sourcing, evaluating, negotiating, and closing collaborations and licensing deals. Manage transactions end-to-end, coordinate cross-functional diligence, prepare partnering materials and financial analyses (NPV, forecasts, comparables), negotiate agreements, and represent the company at industry events to build strategic partnerships.

The Director, Trial Master File will lead TMF platform implementation, oversee compliance, standardize processes, and ensure inspection readiness across clinical operations.

Provide strategic and operational leadership for study start-up activities in clinical programs, ensuring compliant site activation and timely execution of trial initiatives.

Serve as scientific and operational lead for outsourced GLP and non-GLP toxicology studies, liaising with CROs, reviewing protocols and data, monitoring study conduct and quality, managing timelines and risks, reviewing reports, maintaining audit-ready study documentation, and representing Preclinical Safety on cross-functional teams.