Top Remote Senior Machine Learning Engineer Jobs in Boston, MA

Design, build, and support high-throughput, low-latency LLM inference and data pipelines; collaborate with data scientists to post-train and evaluate models; implement scalable, production-ready systems with strong testing, monitoring, and performance focus; mentor engineers and iterate on architecture, reliability, and user-facing AI applications.

Create, solve, review, and validate coding-heavy machine learning tasks for AI training. Build and optimize models, training and inference workflows, data pipelines, evaluation systems, and reproducible Python workflows. Diagnose numerical and system-level failures, improve memory use and throughput, and verify technical correctness while working with coding agents.

Develop and productize machine learning models for autonomous vehicle perception, including LiDAR and camera perception, sensor fusion, detection, classification, segmentation, and tracking. Build scalable data, training, metrics, and performance workflows, and implement efficient C++ code for the NVIDIA DRIVE AV platform. Collaborate across engineering teams, track advances in machine learning, and optimize models for real-time embedded inference.

Design and build a production-grade AI memory and retrieval engine for personalized, privacy-preserving LLM experiences. Responsibilities include developing multi-tier storage and hybrid retrieval pipelines, memory extraction and classification, adaptive updates, evaluation frameworks, and reliability safeguards. The role researches advanced memory architectures, supports agentic workflows and tool integrations, collaborates with product management, and owns production operations. Strong software engineering, Python, NLP/ML, vector database, LLM orchestration, privacy, and RAG expertise are required.

Build and maintain core infrastructure for developing, training, evaluating, deploying, and operating machine learning models and pipelines for Atlassian’s GenAI products. Solve complex software infrastructure and architecture challenges, lead engineers through technical projects from design to launch, and collaborate with internal teams and customers. The role involves large-scale distributed systems, data processing, cloud platforms, CI/CD, and machine learning lifecycle support.

Own the full lifecycle of production classification and detection models, including transformer fine-tuning, entity detection, behavioral risk scoring, training, serving, versioning, evaluation, drift detection, and retraining. Build SageMaker-based ML systems and define output contracts supporting audit and policy enforcement. Lead the evaluation harness and mentor a co-op while operating as the company’s sole ML engineer.

Design and deploy production recommendation and retrieval engines, build data orchestration pipelines for multiple modalities, implement agentic workflow frameworks, and prototype, optimize, and scale models with monitoring, governance, and low-latency SLAs.

Build and improve machine learning systems for ad ranking, relevance, personalization, and optimization. Responsibilities include feature pipelines, model training and evaluation, active learning, LLM-assisted labeling and synthetic data generation, experimentation, and low-latency production inference. The role partners with product, data, and platform teams to improve advertiser performance and user engagement while maintaining reliability, latency, and data quality.

Build and deploy scalable AI and machine learning products for clinical research, including patient recruitment, enrollment forecasting, and study feasibility. Develop ML models, LLM-powered agents, data pipelines, and MLOps infrastructure using cloud services and CI/CD automation. Collaborate with cross-functional teams to integrate AI into clinical research workflows, monitor model performance, and advance reliable, unbiased solutions that improve patient outcomes.

Own and improve Quora’s second-phase ranking models for feed and digest experiences. Build end-to-end machine learning systems covering data pipelines, candidate extraction, feature engineering, model training, and production integration. Identify new product applications for machine learning, develop efficient algorithms with other ML engineers, and contribute methodologies for large-scale recommendation systems.

Build and operate production machine learning systems for Safety AI, including low-latency APIs, data pipelines, model serving, evaluation, monitoring, and rollout infrastructure. Process large-scale camera and telematics data, optimize cloud and edge-to-cloud execution, track model performance and drift, and partner with applied scientists, firmware engineers, platform teams, and product managers to deliver reliable safety features.

Build and ship production AI systems for enterprise portfolio and planning workflows. Develop anomaly and signal detection, LLM-powered insight synthesis, natural-language planning rule translation, evaluation frameworks, and MCP tools. Partner with external AI providers initially, then establish internal standards for prompt design, model selection, agent architecture, reliability, and evaluation. Collaborate closely with product, design, and domain engineering teams.

Lead AI/ML initiatives for Air Force condition-based maintenance, from predictive model development through production deployment. Architect data pipelines, develop machine learning, deep learning, NLP, and generative AI solutions, and build knowledge graph capabilities. Provide technical leadership, integrate models into applications and workflows, and monitor data quality, model performance, drift, and bias. Collaborate with engineering, cloud, software, and product teams while supporting defense aviation logistics and sustainment missions.

Own the end-to-end machine learning and LLM lifecycle, taking models and agentic AI workflows from experimentation into reliable, scalable production. Design MLOps infrastructure, serving, orchestration, CI/CD, evaluation, observability, and GPU optimization. Build self-service tooling and establish LLMOps standards while partnering with engineering and business teams. The role is fully remote and involves up to 10% travel.

Design and build production-grade AI memory systems, including retrieval pipelines, storage tiers, privacy filtering, memory extraction, adaptive updates, hybrid search, and evaluation frameworks. Ship and maintain LLM-powered features, diagnose RAG and prompt failures, implement agentic workflows and tool integrations, and ensure reliable degradation and fallback strategies. Collaborate with product management to define feasible memory-system capabilities while owning production reliability.

Lead design, development, and production deployment of ML and algorithmic solutions. Own end-to-end ML systems, support distributed production reliability, communicate tradeoffs, and apply generative AI, LLM fine-tuning, RAG, and agentic techniques to product problems.

Build and operate production machine learning systems for Airbnb Payments, including LLM agents, real-time fraud detection, anomaly detection, personalization, and checkout optimization. Design, train, deploy, monitor, and continuously improve batch and streaming AI applications at global scale. Partner with product, engineering, operations, and data science teams, establish model governance and testing standards, and mentor engineers.

Lead end-to-end LLM inference performance across serving systems, models, GPU hardware, and workloads. Define rigorous benchmarks, diagnose bottlenecks from scheduling through kernels and interconnects, optimize single- and multi-node deployments, and deliver production-ready runtimes and configurations. Collaborate with product and infrastructure teams, evaluate inference technologies, and implement runtime fixes. The role requires strong Python engineering, production experience with serving engines such as vLLM or SGLang, GPU profiling, and knowledge of modern inference optimization techniques.

Designs, deploys, and operates production machine learning systems for identity resolution, scoring, deliverability, and personalization. Responsibilities include feature engineering, model training, real-time inference, graph database integration, monitoring, drift detection, retraining, low-latency APIs, and scalable data processing. The role also contributes to MLOps standards, GPU acceleration, and ML architecture while partnering with platform engineering.

Own the production lifecycle of ranking and recommendation models, including training, validation, deployment, monitoring, retraining, versioning, rollback, and retirement. Build scalable Spark-based feature and data pipelines, orchestration workflows, model hubs, observability, CI/CD, and reliability standards. Partner with data science and engineering teams to improve model quality, deployment speed, infrastructure efficiency, and operational resilience while mentoring teammates.

Lead the design, development, deployment, and operation of production-grade generative AI and LLM solutions. Build data and ML pipelines, fine-tune and evaluate models, implement RAG and prompt engineering, and establish MLOps practices on AWS. Drive use cases across insurance workflows, ensure security and responsible AI compliance, mentor engineers, and collaborate with product, engineering, security, finance, and go-to-market teams.

Lead exploration and application of large language models and generative AI for enterprise contact-center automation. Translate research into high-performing, deployable ML systems; contribute across experimentation, implementation, and deployment; collaborate with engineering and product teams; optimize performance; and help shape team strategy, innovation, and professional growth.

Lead exploration and application of large language models and generative AI, translate research into deployable ML systems, and guide strategic direction. Develop solutions across experimentation, implementation, and deployment while collaborating with engineering and product teams to optimize performance and customer outcomes in contact center automation.

Own the complete machine learning model lifecycle, from experimentation and validation through deployment, monitoring, retraining, rollback, and retirement. Build reusable training, evaluation, deployment, orchestration, and CI/CD infrastructure. Establish model promotion standards, versioning, lineage, monitoring, alerting, and incident-response processes. Partner with data scientists to preserve scientific validity, improve reliability and efficiency, support delayed-label use cases, mentor teammates, and define MLOps priorities.

Own the production lifecycle for machine learning and LLM-backed systems, including training and post-training pipelines, inference serving, model releases, monitoring, retrieval infrastructure, and cost and latency optimization. Partner with AI researchers and engineering teams to move prototypes into reliable production capabilities across customer tenants. Develop ETL and GraphQL features, enforce tenant isolation, and support deployments in regulated or customer-controlled environments.