Staff Product Manager, Genomics GenAI

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

Are you a visionary product leader passionate about transforming precision medicine and revolutionizing healthcare with groundbreaking AI?

Recent advancements in underlying technology, particularly Generative AI, present an unprecedented opportunity to fundamentally reshape clinical care. Tempus's proprietary platform orchestrates an entire ecosystem of real-world evidence, delivering real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

As Tempus continues to pioneer the application of AI in healthcare, we are seeking an exceptional Staff Product Manager - Genomics GenAI. This role is paramount to defining, shaping, and driving the strategic vision for how Generative AI fundamentally transforms our Genomics engineering efforts. You will be instrumental in solving highly complex, ambiguous, and novel challenges to simplify the operationalization of new assays at scale, drastically reducing manual processes and accelerating our mission to improve patient outcomes through data and technology.

This role is ideal for a seasoned, highly autonomous, and technically proficient self-starter who thrives in deeply ambiguous and intensely cross-functional settings. You'll serve as a thought leader and key influencer, partnering closely with diverse internal teams including lab operations, bioinformatics, clinical, legal, reporting, and core software engineering, to architect and refine transformative GenAI workflows. This means not only translating complex, often uncharted requirements into clear, enterprise-wide roadmaps but also owning mission-critical, 0-to-1 launches from conception through delivery, all while defining the future of genomics at Tempus.

What You'll Do:

Strategic Vision & Innovation

• Define and champion the long-term strategic vision for GenAI tools within the Genomics engineering and broader product organization, ensuring alignment with Tempus’s overarching genomics, AI, and company-wide strategies.

• Translate deeply complex scientific and technical challenges into clear, actionable product strategies and groundbreaking GenAI-driven solutions that address fundamental pain points and unlock new capabilities.

• Identify and drive architectural shifts and foundational improvements that leverage GenAI to enhance efficiency, accuracy, and scalability across the entire genomics platform.

• Proactively identify and validate new frontiers for GenAI application in genomics, moving beyond existing problems to create novel, high-impact product offerings.

Product Development & Enablement at Scale

• Lead the end-to-end product lifecycle for complex GenAI solutions, from early-stage ideation, technical prototyping, and experimentation to full-scale deployment, adoption, and continuous optimization.

• Collaborate deeply with core product and engineering teams, providing technical guidance and strategic direction to design, develop, and implement GenAI-powered tools and workflows that redefine industry standards.

• Drive significant system enhancements that utilize GenAI to drastically improve turnaround time for launching assays and reduce manual work in test production, with a clear focus on measurable business impact.

• Leverage advanced analytics, deep user insights, and industry trends to propose, champion, and lead transformative improvements to core genomics infrastructure and tooling through innovative GenAI applications.

Cross-functional Leadership & Organizational Influence

• Proactively engage with executive stakeholders and key internal thought leaders to gather insights, define enterprise-level requirements, and ensure GenAI solutions meet the evolving needs of diverse, high-impact user groups.

• Represent and advocate for GenAI product needs in high-stakes, cross-team forums, influencing dependencies, securing resources, and ensuring strategic alignment across the organization.

• Cultivate understanding, define best practices, and actively mentor and guide product managers and other product leaders on strategic approaches to leveraging GenAI for innovation in Genomics workflows and tooling, accelerating organizational capabilities.

Executive Communication & Strategic Documentation

• Maintain highly organized, transparent, and comprehensive strategic product plans, architectural decision logs, and visionary requirements documentation for complex GenAI initiatives.

• Communicate progress, critical blockers, strategic risks, and nuanced technical details to a wide array of stakeholders, including senior executives, proactively and with exceptional clarity, navigating extreme ambiguity with a compelling vision.

• Champion transparent, repeatable, and scalable documentation practices that enable broad organizational understanding and adoption of all GenAI-driven solutions.

Qualifications:

• 8+ years of product management experience, with a significant portion dedicated to Generative AI products or large-scale AI/ML applications.

• Proven track record of defining, launching, and scaling highly complex GenAI solutions within an engineering or product development context, demonstrating significant, measurable business and strategic impact.

• Demonstrated ability to define product strategy and drive execution in highly ambiguous and uncharted territories with minimal oversight. You excel at creating structure and clarity where none exists.

• Deep technical expertise in Generative AI models, platforms, and their practical application. You can engage in architectural discussions and influence technical strategy.

• Exceptional execution mindset with a proven ability to lead and deliver highly complex, cross-functional, and critical initiatives across multiple teams.

• Comfort working with highly technical stakeholders and solving systems-level challenges, particularly within the genomics, bioinformatics, or other complex scientific domains.

• Outstanding written and verbal communication skills, including the ability to distill complex technical and strategic information for diverse audiences, especially in high-stakes or regulated contexts.

• Highly organized with strong attention to detail and a pervasive bias toward clarity, structure, and scalable processes.

• Demonstrated leadership experience, including actively mentoring and developing other product managers and contributing to the overall product organization's capabilities.

• A background in genomics, molecular biology, biomedical engineering, or life sciences is a significant plus.

#LI-SH1

CHI: $130,000-$180,000

The expected salary range above is applicable if the role is performed from Illinois and may vary for other locations (California, Colorado, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.