SOPHiA GENETICS Logo

SOPHiA GENETICS

Senior Software Engineer

Posted 58 Minutes Ago
Be an Early Applicant
Hybrid
Boston, MA, USA
71K-144K Annually
Senior level
Hybrid
Boston, MA, USA
71K-144K Annually
Senior level
Design, develop, and optimize scalable backend services, APIs, middleware, and core platform components. Build hospital-system integrations, improve performance for high-volume medical data, maintain monitoring and observability, and automate deployment pipelines and infrastructure. Support live customer integrations, implement enhancements, and contribute to system architecture, reliability, and cost efficiency across cloud-native, containerized environments.
The summary above was generated by AI
Are you an experienced Software Engineer with a passion for building and improving scalable, high-performance systems? Are you looking for a team that embraces fresh ideas, encourages an agile approach, and ensures your voice is heard and your contributions truly make an impact?
If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Software Engineering team as our new Senior Software Engineer, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide.
This is a hybrid opportunity, requiring 3 days onsite our corporate office in Boston, MA.
Our Mission
We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe.
Your Mission
As a Senior Software Engineer, you will be responsible for designing, developing, optimizing, and continuously improving software solutions, while contributing to technical initiatives and ensuring the solutions meet both business and technical requirements.
Your work will enable healthcare institutions in setting up diagnostic workflows that integrate seamlessly with the SOPHiA DDM platform - processing high-volume of medical data and bringing insights for oncologists via a streamlined process.
These components span the complete technology stack of SOPHiA DDM as well as the middleware layer responsible for integration and connectivity between SOPHiA DDM and external hospital systems. Your expertise will ensure these components not only scale effectively but also remain efficient in terms of performance and cost, while being extended with features required for new integrations.
The value you bring
  • Design, develop, and continuously improve robust services that are scalable and efficient while fitting into overall system architecture
  • Implement new features and enhancements across SOPHiA DDM core components, public API as well as middleware layer to enable setup of new integrations with external hospital systems of our customers
  • Support existing live integrations with customers, propose and implement enhancements based on customer feedback and to achieve system robustness goals
  • Ensure components perform reliably under high workloads, optimize system performance, resource utilization, and task execution times, contribute to improvements in system stability
  • Optimize deployment workflows, automate pipelines, and enhance infrastructure management for efficient and reliable application deployment
  • Implement and maintain monitoring systems to track performance and identify bottlenecks, use existing observability tools like Grafana and Loki to provide insights into operational health
  • Use cutting edge AI tools and software engineering best practices to boost productivity across all workstreams

Requirements
    • Minimum of 5 years' experience in a comparable role, holding a bachelor's or master's degree (or higher)
    • Solid proficiency in Java for backend services
    • Solid understanding and extensive working experience with microservices architecture
    • Solid experience with public APIs including API definition and change management
    • Proficiency with databases like MySQL, MariaDB, and DuckDB, including design and query optimization
    • Power user of latest AI tools and agent orchestration in all stages of software life cycle
    • Knowledge of HL7 and FHIR standards for healthcare data exchange is a strong plus
    • Familiarity with Linux environments and GitLab for version control and CI/CD pipelines
    • Experience in optimization of system performance, manage resources effectively, and improve execution time - esp. when dealing with large data volumes
    • Experience with scalable architecture, particularly in cloud environments and containerized infrastructure
    • Familiarity with monitoring and observability tools such as Grafana and Loki
    • React.js experience for front end development is a strong plus
    • Experience with Micronaut for developing microservices and backend solutions is a strong plus.
    • Knowledge of Kafka is a plus
    • Experience in genomics is beneficial

Benefits
You will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth.
Business recognition and accolades include:
  • World's most innovative companies (Top 10)
  • World's smartest companies (Top 50)
  • 100 Best Places to Work in Boston
  • Top 10 European Tech Startup
  • Top 10 European biotechs startup to watch
  • Top 25 East-Coast Biotech to watch

Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview:
US:
Outstanding Medical, Dental & Vision with 90% Employer Contribution
Company matched 401K at 4%
Company-paid short & long-term disability insurance
FSA commuter benefits
20 Days PTO, increasing to 25 with tenure; 5 Days Sick and 14 Public Holidays
Free EAP
Our DNA
Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous
Our Virtues
At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn.
At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal
The Process
We use the power of AI to help our partners make decisions. If you're utilizing AI in your search and application process, why not use some of these prompts, or read our AI guide.
'What impact can I expect to have on the world by working at SOPHiA GENETICS?'
'I have an interview with SOPHiA GENETICS. What should I know before I meet with them?'
'I am a *job title* - What can SOPHiA GENETICS offer my career?'
Apply now with your CV and any supporting information.
Suitably qualified candidates will be invited through an interview and screening process where you will speak with members of our Talent Acquisition Team, the hiring leader alongside key colleagues and stakeholders from across the business.
If you need additional support or accommodations for accessibility, please contact our TA team for assistance on [email protected]. SOPHiA GENETICS recruiters only contact candidates from @sophiagenetics.com addresses and never request payment at any stage. Verify any offer before responding.
We appreciate the value external partners can bring, but we operate a direct-hiring model and we are not looking to utilize agency support at this time. All hiring is controlled by Talent Acquisition, potential partners should liaise through TA and not our hiring teams please.
Starting Date: ASAP
Location: Boston, MA - Hybrid 3x/week in office
Contract: Permanent
MA Pay Range: USD 71'250-143'750
Disclaimer: The estimated pay range represents a good faith estimate of what the Company expects to pay a successful applicant for the listed position and applies specifically to candidates based in Massachusetts. Due to various factors, the estimated pay range may vary in other locations. Should the level or location of the role change during the hiring process, the applicable base range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual's qualifications, job related skills, years of experience, location, relevant education or training, internal equity, and alignment with market data. The range does not include benefits, and if applicable, bonus, commission, or equity.
HQ

SOPHiA GENETICS Boston, Massachusetts, USA Office

401 Park Drive, Boston, MA, United States, 02215

Similar Jobs at SOPHiA GENETICS

Senior level
Artificial Intelligence • Big Data • Healthtech • Software • Biotech
Leads business development and strategic account growth with pharmaceutical and biotechnology partners across the U.S. West and Central regions. Responsibilities include acquiring customers, building pipelines in Salesforce, developing proposals, advancing precision medicine and genomics opportunities, negotiating and closing projects, and collaborating with scientific, commercial, and operational teams. The role focuses on NGS-based assays, biomarker discovery, clinical trial solutions, and companion diagnostics, with approximately 30% domestic and international travel.
Top Skills: Biomarker DiscoveryClinical Trial AssaysCompanion Diagnostics (Cdx)CtdnaGenomic AssaysLiquid BiopsyNext-Generation Sequencing (Ngs)SalesforceSophia Ddm
7 Days Ago
Remote or Hybrid
Boston, MA, USA
Senior level
Senior level
Artificial Intelligence • Big Data • Healthtech • Software • Biotech
Leads end-to-end IVD, companion diagnostic, clinical trial assay, tumor profiling, and SaMD development programs. Aligns internal cross-functional teams and biopharma partners across strategy, validation, clinical operations, regulatory submission, manufacturing, and commercialization. Owns governance, milestones, budgets, resources, risks, and partner relationships while delivering programs through regulatory approval or pivotal clinical trials.
Top Skills: Analytical ValidationAssay DevelopmentBioinformaticsBlaClinical ValidationCompanion Diagnostics (Cdx)Design ControlsEu IvdrFda Regulatory RequirementsIndIvdMaaNdaPhase I/Ii/IiiSoftware As A Medical Device (Samd)
10 Days Ago
Hybrid
Boston, MA, USA
88K-168K Annually
Expert/Leader
88K-168K Annually
Expert/Leader
Artificial Intelligence • Big Data • Healthtech • Software • Biotech
Lead North American field marketing, connecting marketing, sales, and SDR teams to generate qualified pipeline. Manage inbound leads from events and campaigns, improve sales follow-up, plan targeted account-based outbound campaigns using 6sense and marketing automation, and coordinate execution across a decentralized sales organization. The role also manages two SDRs and an Events Lead while focusing on conversion quality and pipeline outcomes in complex healthcare and life sciences buying environments.
Top Skills: 6SenseAccount-Based MarketingMarketing Automation

What you need to know about the Boston Tech Scene

Boston is a powerhouse for technology innovation thanks to world-class research universities like MIT and Harvard and a robust pipeline of venture capital investment. Host to the first telephone call and one of the first general-purpose computers ever put into use, Boston is now a hub for biotechnology, robotics and artificial intelligence — though it’s also home to several B2B software giants. So it’s no surprise that the city consistently ranks among the greatest startup ecosystems in the world.

Key Facts About Boston Tech

  • Number of Tech Workers: 269,000; 9.4% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Thermo Fisher Scientific, Toast, Klaviyo, HubSpot, DraftKings
  • Key Industries: Artificial intelligence, biotechnology, robotics, software, aerospace
  • Funding Landscape: $15.7 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Summit Partners, Volition Capital, Bain Capital Ventures, MassVentures, Highland Capital Partners
  • Research Centers and Universities: MIT, Harvard University, Boston College, Tufts University, Boston University, Northeastern University, Smithsonian Astrophysical Observatory, National Bureau of Economic Research, Broad Institute, Lowell Center for Space Science & Technology, National Emerging Infectious Diseases Laboratories

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account