Senior Scientist I Immunohistochemistry

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Are you an experienced and motivated immunohistochemistry scientist looking to contribute to innovative drug discovery programs in a highly collaborative and dynamic environment? Join our Pathology team and help advance research that informs target validation, target distribution, animal model development, pharmacology, and combination therapy strategies.

The Pathology team is seeking an immunohistochemistry scientist to perform single-plex and multiplex immunohistochemistry and immunofluorescence assays using advanced multiplex immunofluorescence (mIF) platforms. The successful candidate will work closely with study pathologists, project teams, histotechnologists, and fellow scientists to develop robust assays and generate high-quality, quantitative data that support critical research decisions.

This role requires strong technical expertise, attention to detail, independent judgment, and the ability to manage multiple priorities in a fast-paced, team-oriented environment.

Key Responsibilities:

• Independently design and execute single-plex and multiplex immunohistochemistry and immunofluorescence assays ensure assay execution meets established quality and performance criteria
• Partner with pathologists and project teams to determine the most appropriate assay design and experimental approach for key project questions, including questions related to target validation and expression aligned with project objectives and timelines 
• Develop, optimize, and troubleshoot assays using the Opal and Leica Bond Rx platforms with minimal input from pathologists
• Analyze results and present clear, well-organized findings with representative images and quantitative data
• Provide technical leadership in IHC panel design, assay optimization, and complex assay development
• Apply a thorough understanding of image analysis to support the complete assay-development process, from assay design through endpoint generation
• Mentor junior scientists and promote consistent, high-quality laboratory practices
• Evaluate emerging technologies and communicate relevant opportunities to the team
• Use Sample Manager, DreamPath, and other laboratory systems to document and track activities
• Maintain accurate, timely, and compliant experimental records

• Bachelor’s degree in biology/chemistry or related field with 10 years of experience or master’s degree with 8 years of experience
• Bachelor’s or master’s degree in biology, pathology, life sciences, or a related discipline, with relevant industry experience
• Demonstrated experience performing immunohistochemistry and immunofluorescence assays
• Thorough knowledge of the Opal mIF platform, including assay development, optimization, and troubleshooting
• Experience with image analysis and the ability to understand how image-analysis methods affect assay quality and quantitative endpoints
• Ability to work independently, prioritize workload, and manage multiple projects and deadlines
• Strong attention to detail and commitment to generating accurate, reproducible, and well-documented results
• Excellent communication and collaboration skills, including the ability to present technical findings clearly to cross-functional project teams
• Microsoft office skills 

Preferred Qualifications:

• Qualification in IHC (QIHC)
• Experience with the COMET multiplex immunofluorescence platform
• Knowledge of spatial biology, quantitative pathology, or image-analysis software
• Familiarity with Sample Manager, DreamPath, or comparable laboratory tracking systems
• Experience mentoring junior scientists or providing technical guidance to colleagues
• This is an exciting opportunity to join a motivated and collaborative team of immunohistochemistry scientists and histotechnologists. If you enjoy solving technical challenges, applying emerging technologies, and working with multidisciplinary teams to advance drug discovery, we encourage you to consider joining us.

Other Desirable Attributes:

• Well organized
• Attention to detail
• Adherence to established protocols and laboratory documentation requirements
• Ability to work and effectively communicate within a team environment
• Ability to handle multiple projects simultaneously
• Delivery of high-quality, timely results
• Excellent oral and written communication skills
• Enthusiastic
• Independent, analytical, innovative thinker
• Proficiency with MS office-Excel, OneNote

Significant Work Activities and Conditions:

• Continuous standing for prolonged periods  (more than 2 consecutive hours in an 8-hour day)
• Routine work with chemicals

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at  the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors  including  geographic location, and we may ultimately  pay more or less than the posted range. This range may be  modified in the future. ​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

• This job is eligible to  participate in our short-term incentive programs.  ​

Note: No amount of pay is  considered to be wages or compensation until such amount is earned,  vested,  and determinable. The amount and availability of  any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a   particular employee  remains in the Company's sole and absolute discretion unless and until paid and may be  modified at the Company’s sole and absolute discretion,  consistent with applicable law. ​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

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