Senior Scientist, Biology

ROLE SUMMARY
The Internal Medicine Research Unit (IMRU) is strategically focused on discovering novel therapies to prevent or treat cardiometabolic diseases. Our mission is to build a world-class research team dedicated to deepening the mechanistic understanding of disease pathogenesis.
As a member of the discovery biology team, the Senior Scientist will play a pivotal role in the drug discovery process-from ideation and hypothesis generation to the identification and validation of therapeutic targets and disease-related biomarkers.
This individual will contribute to experimental strategy and execution and work closely with other scientists across disciplines. Expertise in cardiovascular biology is essential, and familiarity with dysmetabolic pathophysiology is highly desirable. The role also involves fostering collaborations with academic institutions and internal partners across the Pfizer network.
Daily interactions will occur within a dynamic and supportive environment of innovative scientists. Success in this role requires strong self-motivation, excellent communication and interpersonal skills, and the ability to influence and collaborate effectively within a team setting.
ROLE RESPONSIBILITIES
Successful candidates will be expected to:

• Apply scientific expertise and creative thinking to develop strategies for identifying and validating therapeutic targets aligned with IMRU priorities.
• Stay abreast of cutting-edge developments in preclinical and translational science and integrate relevant advances into portfolio programs.
• Design and execute rigorous in vitro, ex vivo, and in vivo experiments, including data analysis and interpretation.
• Support the development of junior scientists through mentorship and collaborative engagement.
• Translate experimental findings to advance understanding of cardiovascular biology and complex physiological systems in disease and therapeutic contexts.
• Build and maintain collaborations with academic partners and internal Pfizer scientists.
• Communicate research findings through peer-reviewed publications, scientific presentations, and internal leadership briefings.
• Uphold the highest standards of scientific integrity, quality, and compliance with regulatory and ethical guidelines.

QUALIFICATIONS

• PhD in cardiovascular biology, cardiometabolic diseases, or a related field, with 0-3 years of postdoctoral research experience.
• Demonstrated ability to critically evaluate scientific data and formulate innovative hypotheses.
• Strong track record of scientific contributions, as evidenced by peer-reviewed publications and presentations at scientific conferences.
• Hands-on experience with in vitro, in vivo, and ex vivo models relevant to cardiovascular disease.
• Proven ability to work independently and collaboratively within interdisciplinary research teams.
• Capacity to manage multiple projects simultaneously with scientific rigor and adaptability.
• Excellent written and verbal communication skills, with the ability to engage effectively across scientific disciplines.
• Prior experience in drug discovery is preferred but not required.

PHYSICAL/MENTAL REQUIREMENTS
Sitting, standing, walking, basic lab bench activities, ability to perform complex data analysis
ADDITIONAL INFORMATION
Relocation is support available.
Work Location Assignment: Full-time, on premise.
Last day to apply September 14th, 2025
The annual base salary for this position ranges from $90,900.00 to $151,500.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Research and Development