Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Senior Project Manager: Full-Time | [PCORI-funded, Term-limited position]
About the Role:
We are seeking a highly organized and motivated Senior Project Manager to administer day-to-day operations of a large, multi-site Patient-Centered Outcomes Research Institute (PCORI)-funded study. The study is the Supporting Practices in Respecting Elders (SPIRE) project (https://www.spire-study.org/) and is funded as a multi-year comparative effectiveness trial in primary care practices across four health systems. This individual will play a critical role in ensuring successful execution of a complex, stakeholder-engaged research initiative designed to improve healthcare delivery and patient outcomes for older adults with complex care needs. The ideal candidate has experience managing large federally or foundation-funded research studies or improvement initiatives, excels in cross-institutional collaboration, and brings a deep commitment to person-centered care.
Key Responsibilities:
Project Oversight & Implementation
• Leads overall project management, including timeline tracking, budget oversight, milestone monitoring, and deliverable completion.
• Coordinates site engagement activities across multiple different health systems and clinical practices.
• Assists the leadership team in ensuring compliance with PCORI and institutional requirements including IRB compliance, reporting, and data safety protocols.
Team and Stakeholder Coordination
• Facilitates communication across multidisciplinary teams, including SPIRE study core leadership, site-based principal investigators, champions, clinicians, community partners, and stakeholders.
• Supports the implementation of learning collaborative activities, SPIRE study meetings, and stakeholder engagement meetings.
• Works closely with project Clinical Research Coordinators on study deliverables to clinical sites and funders.
Study Infrastructure & Data Coordination
• With oversight by the Project Director, develops and maintains project management systems for task tracking, documentation, and communication.
• Collaborates with the Study PIs and Project Director to develop streamlined methods for study activities, including recruitment and enrollment tracking, data collection, data reporting, and quality assurance processes.
• Collaborates with SPIRE study leadership to support fidelity monitoring, site-level adaptation, and tracking of implementation facilitators, barriers, and lessons learned.
Reporting & Communication
• Assists with drafting and coordinating progress reports, grant deliverables, and presentations to funders and stakeholders.
• Assists with dissemination of findings, including manuscript support, public-facing materials, and presentations.
Preferred Qualifications:
• Master’s Degree in Public Health, Health Policy, Health Services Research, or a related field
• Minimum 5–7 years of relevant experience managing large-scale research or healthcare implementation projects
• Strong understanding of patient-centered outcomes research, stakeholder engagement principles, and real-world evidence generation.
• Proven ability to manage complex, multi-site teams and balance competing priorities.
• Excellent organizational, writing, and interpersonal communication skills.
• Proficiency with research and project management tools (e.g., Airtable, REDCap, Smartsheets) and collaborative platforms (e.g., Zoom, Microsoft Teams).
Preferred Experience:
• Experience with multi-site healthcare studies, improvement initiatives, and research or evaluation methods
• Prior experience working with multiple stakeholder advisory groups.
• Experience in aging, serious illness care, primary care, or chronic disease a plus.
Job Summary
Responsible for all aspects of project administration and coordination of multiple clinical trials including multi-center trials. Duties include the review of all proposals, budgets, and contracts and tracking of all milestones and timelines. The development of study related documents, completion of data management functions, and reporting of safety and endpoints to the study sponsor and IRB. For multi-site trials, the overall direction of the clinical sites for protocol adherence is under the direction. Accountable for assuring that the project team that he/she leads meets all deadlines and is also required to maintain a close effectual working relationship with Sponsors, Study Coordinators, and Principal Investigators.Does this position require Patient Care?
No
Essential Functions
-Coordinate the development of investigator-initiated and industry sponsored project documents and timelines and manage any changes, including future timeline changes that may result from changes in scope, delays in schedule or resource constraints.
-Is responsible for all regulatory maintenance for assigned clinical research and trial projects including IRB submissions, biosafety committee submissions, FDA submissions and reporting, funding agency reporting, clinicaltrials.gov record maintenance, and other related tasks on assigned projects.
-Monitors and manages sub-sites on multi-center clinical research projects including facilitating regular sub-site status meetings, overseeing sub-site data collection and quality, and collecting sub-site regulatory documentation and ensuring compliance.
-Develop and finalize complete project plans with formalized project milestones and deliverables.
-Facilitate and maintain records of all internal and external communication relevant to assigned clinical trials.
-Responsible for Project Operating Planning Manual development.
-Present and lead presentations at site initiations or trial kick off meetings.
Qualifications
Education
Bachelor's Degree Related Field of Study required
Can this role accept experience in lieu of a degree?
No
Licenses and Credentials
Experience
Clinical Research Experience 3-5 years required
Knowledge, Skills and Abilities
- Must be able to prioritize multiple, competing tasks with excellent organizational skills.
- Strong interpersonal and leadership skills with ability to train, supervise, mentor and support team members effectively.
- Excellent judgment and ability to make independent effective decisions in appropriate situations.
- Team building and conflict management skills.
- Ability to promote collaboration and communication within and beyond the team.
Additional Job Details (if applicable)
Physical Requirements
- Standing Frequently (34-66%)
- Walking Frequently (34-66%)
- Sitting Occasionally (3-33%)
- Lifting Frequently (34-66%) 35lbs+ (w/assisted device)
- Carrying Frequently (34-66%) 20lbs - 35lbs
- Pushing Occasionally (3-33%)
- Pulling Occasionally (3-33%)
- Climbing Rarely (Less than 2%)
- Balancing Frequently (34-66%)
- Stooping Occasionally (3-33%)
- Kneeling Occasionally (3-33%)
- Crouching Occasionally (3-33%)
- Crawling Rarely (Less than 2%)
- Reaching Frequently (34-66%)
- Gross Manipulation (Handling) Frequently (34-66%)
- Fine Manipulation (Fingering) Frequently (34-66%)
- Feeling Constantly (67-100%)
- Foot Use Rarely (Less than 2%)
- Vision - Far Constantly (67-100%)
- Vision - Near Constantly (67-100%)
- Talking Constantly (67-100%)
- Hearing Constantly (67-100%)
Remote Type
Work Location
Scheduled Weekly Hours
Employee Type
Work Shift
Pay Range
$77,396.80 - $126,401.60/AnnualGrade
8At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
EEO Statement:
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
Top Skills
Mass General Brigham Somerville, Massachusetts, USA Office
399 Revolution Dr, Somerville, Massachusetts, United States, 02145
Mass General Brigham Boston, Massachusetts, USA Office
800 Boylston St, Boston, Massachusetts, United States, 02199
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