Senior Manager, Talent Acquisition

Company Overview

Tango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.

Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.

This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.

The Tango labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts

Summary

The Senior Manager, Talent Acquisition will report to the Head of Talent Acquisition and act as a strategic and hands-on partner in shaping Tango’s hiring strategy and elevating recruiting excellence. This newly created role manages full-cycle recruiting across multiple functions, ensuring high-quality execution while closely aligning with company-wide priorities. Beyond leading searches, the Senior Manager will champion initiatives that enhance Tango’s employer brand, optimize recruiting processes, and deliver exceptional candidate experience.

As Tango continues to grow with multiple ongoing clinical trials and a robust pipeline of innovative programs, this role will play a critical part in translating business needs into effective hiring strategies that enable the company to scale successfully and compete for top talent in a dynamic biotech environment.

Your role:

• Drive and support strategic hiring plans across critical domains, aligned with Tango’s growth trajectory and workforce planning
• Partner extensively with hiring managers, HR Business Partners, and functional leaders as a strategic talent advisor providing market and talent insights
• Leverage talent intelligence and market mapping to identify and engage top talent, building diverse pipelines of active and passive candidates
• Optimize recruiting tools, systems, and workflows to improve efficiency, data accuracy, and scalability
• Partner with business and HR to continue to embed structured, candidate-centered selection practices that ensure consistent, high-quality hiring decisions and positive experience
• Collaborate with the communications team and stakeholders to deliver creative recruitment campaigns and talent attraction initiatives that enhance immediate hiring outcomes and elevate Tango’s employer brand
• Represent Tango as an ambassador at industry events, conferences, and networking forums
• Track, analyze, and present key hiring metrics to business stakeholders, driving continuous improvement and operational excellence in recruitment practices
• Oversee the management of external search firm partnerships for hard-to-fill roles, ensuring quality outcomes within budget in a manner consistent with Tango’s employer brand
• Support cross-functional HR initiatives and lead ad hoc projects as needed

What You Bring:

• Bachelor’s degree; advanced degree preferred
• 6+ years of progressive full-cycle Talent Acquisition experience, ideally with both agency and sponsor side exposure
• 4+ years in biotechnology with a successful track record of quality hires ideally across functions from R&D to commercial
• Strong business acumen and consultative influence with senior executives, experienced in navigating complex, matrixed environments
• Ability to translate business strategy into actionable talent acquisition plans and deliver results
• Exceptional market research, headhunting, networking, and sourcing skills
• Strong data-driven recruiting skills, including metrics, analytics, and dashboard creation to support evidence-based hiring decision
• Experience creating compelling employer branding campaigns that engage top talent
• Skilled in project management of talent acquisition programs, ensuring timely and effective execution
• Advanced Excel required, Power BI or equivalent preferred
• Proficiency with ATS and onboarding technologies (Greenhouse preferred), and LinkedIn Recruiter
• Proactive and adaptable; a bias for action and learning agility
• Collaborative and strategic acumen; the ability to balance strategic thinking with hands-on execution

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.