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Kelonia Therapeutics

Scientist II/Sr. Scientist, In Vivo Pharmacology

Posted 14 Days Ago
Be an Early Applicant
In-Office
Boston, MA
Mid level
In-Office
Boston, MA
Mid level
Lead in vivo pharmacology studies, develop murine models, mentor junior colleagues, and ensure compliance with regulations at Kelonia Therapeutics.
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Here at Kelonia Therapeutics, we aren’t just a clinical company; we’re trailblazers in viral engineering, pushing the boundaries of in vivo lentiviral gene and cell therapy. We're not just a team; we're dreamers on a mission to bring the promise of cell and gene therapy to every patient in need.

We've gathered a group of pioneers in cell and gene therapy to lead our journey, with extraordinary scientific founders at the helm, providing the cutting-edge technology that sets us apart. We're not just building a company; we're cultivating a culture that values both skill and care.

What You'll Do:

  • Lead in vivo murine model development and characterization for various programs.
  • Design, plan, conduct, document, analyze and interpret preclinical in vivo studies in support of various programs.
  • Work collaboratively to plan, execute, and analyze ex vivo characterization of multiple parameters such as bio-distribution and transduction efficiency.
  • Prepare and present data and interpretations to cross-functional stakeholders.
  • Help draft technical reports that document in vivo studies.
  • Mentor and guide junior colleagues.

What You'll Bring:

  • Strong scientific expertise in Pharmacology or related discipline, PhD, and non-PhD candidates encouraged to apply (level based on experience)
  • In-depth experience in animal handling and drug administration including i.v./i.p./s.c. dosing, in-study blood sampling, IVIS imaging, necropsy, tissue harvest and processing.
  • Understands and implements study protocols in accordance with regulatory requirements for compliance with IACUC guidelines.
  • Demonstrated initiative in experimental design, troubleshooting, and performing robust data analysis.
  • Excellent organizational and documentation skills.
  • Adaptable analytical person with a get-it-done attitude.
  • Experience with humanized mouse models, engineered human T cells, and secondary ex vivo assays (eg. multicolor flow cytometry, PCR, MSD, IHC, ISH) is a plus.
  • Ability to work collaboratively, meet deadlines, and prioritize and flexibly balance multiple workstreams.

At Kelonia, we’re serious about balance and growth. You’ll get Flexible Time Off, flexible scheduling that aligns with your needs and our objectives, a competitive benefits package (health, commuter, and more), and great on-site perks that include free parking, a state-of-the-art gym, and a food hall – all within a collaborative, inclusive team that invests in your development and makes big things happen together.
 
Kelonia Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Kelonia does not accept unsolicited resumes from any source other than directly from candidates. 
 
Job Type: Full-time
Work Type: On-Site M-F
Location: Boston, MA

Top Skills

Ihc
Ish
Ivis Imaging
Msd
Multicolor Flow Cytometry
Pcr
HQ

Kelonia Therapeutics Boston, Massachusetts, USA Office

Boston, Massachusetts, United States

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