Lila Sciences Logo

Lila Sciences

Principal Engineer, AI Security

Posted 2 Days Ago
Be an Early Applicant
In-Office
Cambridge, MA, USA
252K-374K Annually
Entry level
In-Office
Cambridge, MA, USA
252K-374K Annually
Entry level
Owns security engineering for AI and ML infrastructure, including training and inference pipelines, model registries, MCP servers, and agent runtimes. Designs security controls, conducts threat modeling and adversarial assessments, maintains compliance, and drives vulnerability remediation. Partners with AI Platform, Research, ML Operations, Science, and AI Safety teams to embed security across data, models, pipelines, and agentic systems.
The summary above was generated by AI

Your Impact at LILA

Lila Sciences is building autonomous systems for scientific discovery, and the AI infrastructure behind that work needs security built in from the start. This role sits on the IT & Security team and owns security engineering for Lila's AI and ML systems, from training and inference pipelines to model registries, MCP servers, and agent runtimes.

As the senior individual contributor for AI security, you will translate the AI security roadmap into delivered controls, drive vulnerability remediation to closure, and reduce risk across the full AI lifecycle: data, models, pipelines, and agentic systems. The work is hands on, with technical depth across cloud security, supply chain security, and AI-specific threat models.

The role is deeply cross-functional. You will partner with AI Platform, AI Research, ML Operations, Science, and AI Safety so security shows up at design time rather than after the fact. Success looks like AI infrastructure that stays continuously compliant, measurable reduction in open risk, and engineering teams that treat security as part of how they build.

What You'll Be Building

  • Turn the AI security roadmap into delivered controls with measurable outcomes
  • Design and implement security controls across training and inference pipelines, model registries, MCP servers, and agent runtimes
  • Keep AI infrastructure continuously compliant against internal standards and applicable frameworks
  • Drive vulnerability remediation across AI infrastructure, models, and dependencies to closure with system owners
  • Reduce risk across data, models, pipelines, and agentic systems through threat modeling, control design, and adversarial assessment
  • Partner with AI Platform, AI Research, ML Operations, Science, and AI Safety so security is embedded at design time

What You'll Need to Succeed

  • Strong background in security engineering, cloud security, or DevSecOps, with hands-on experience securing production infrastructure
  • Working knowledge of AI/ML systems and the ML lifecycle, plus AI-specific risks such as prompt injection, model and data poisoning, insecure agent tooling, and inference-time threats
  • Experience with software supply chain security and dependency and vulnerability management
  • Experience implementing data security controls (classification, data flow mapping, access control, encryption) in cloud environments
  • Proven ability to partner across engineering teams and drive cross-functional remediation to closure
  • Comfort operating with ambiguity in a fast-moving research environment

Bonus Points For

  • Hands-on AWS security experience
  • Experience with SBOM tooling at scale
  • Familiarity with AI governance and assurance frameworks such as NIST AI RMF
  • Experience with MAESTRO-style threat modeling for agentic systems

Compensation

We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.

U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.

Expected Base Salary Range
$252,000—$374,000 USD

About LILA

Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.

LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.

Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.

We’re All In

Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.

A Note to Agencies

Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.

HQ

Lila Sciences Cambridge, Massachusetts, USA Office

Cambridge, MA, United States

Similar Jobs

19 Days Ago
Remote or Hybrid
US
172K-240K Annually
Expert/Leader
172K-240K Annually
Expert/Leader
Information Technology
Owns enterprise AI security assessment, architecture, and control programs. The role evaluates AI systems, vendors, platforms, and shadow AI; designs secure architectures, guardrails, identity models, sandboxes, gateways, and runtime controls; and develops detection and response capabilities for prompt injection, jailbreaks, data leakage, and tool misuse. The engineer partners with governance, identity, platform, engineering, and security operations teams, advises senior leaders, drives remediation, and mentors security professionals.
Top Skills: Ai GatewaysAi GuardrailsAi ObservabilityAi SandboxesAnthropicAWSAzureAzure Ai ServicesData Loss PreventionGCPIdentity And Access ManagementIso/Iec 42001LangchainMcpMicrosoft Copilot StudioMitre AtlasNist Ai RmfOpenaiOwasp Top 10 For Llm ApplicationsSemantic KernelZero Trust
Yesterday
In-Office or Remote
United States
150K-190K Annually
Senior level
150K-190K Annually
Senior level
Digital Media • Fintech • Information Technology • Machine Learning • Financial Services • Cybersecurity • Automation
Leads the design and implementation of security solutions for AI systems across data ingestion, model training, deployment, and runtime. Develops controls against prompt injection, data poisoning, model inversion, data leakage, and unauthorized access. Secures cloud infrastructure, APIs, identities, integrations, and third-party AI platforms; implements monitoring, automated security testing, and incident response. Partners with architecture, engineering, and governance teams to ensure resilient, compliant AI security practices.
Top Skills: Ai/MlAPIsCloud ComputingContainersDatabasesDevOpsEncryptionOrchestration PlatformsPythonSaaSServerlessTokenization
12 Days Ago
In-Office
Cambridge, MA, USA
192K-306K Annually
Expert/Leader
192K-306K Annually
Expert/Leader
Artificial Intelligence • Software
Lead security investigations for AI systems used in scientific discovery. Develop threat models, test defenses through adversarial assessments and technical analysis, define security requirements, evaluate evidence, and drive improvements with Security, Safety, and engineering teams. The role addresses dangerous misuse, model and data compromise, deployment risks, and safeguards for increasingly capable AI systems.
Top Skills: Ai AgentsAi/Ml InfrastructureApplication SecurityIncident ResponseInfrastructure SecurityOffensive SecuritySecurity ArchitectureThreat Modeling

What you need to know about the Boston Tech Scene

Boston is a powerhouse for technology innovation thanks to world-class research universities like MIT and Harvard and a robust pipeline of venture capital investment. Host to the first telephone call and one of the first general-purpose computers ever put into use, Boston is now a hub for biotechnology, robotics and artificial intelligence — though it’s also home to several B2B software giants. So it’s no surprise that the city consistently ranks among the greatest startup ecosystems in the world.

Key Facts About Boston Tech

  • Number of Tech Workers: 269,000; 9.4% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Thermo Fisher Scientific, Toast, Klaviyo, HubSpot, DraftKings
  • Key Industries: Artificial intelligence, biotechnology, robotics, software, aerospace
  • Funding Landscape: $15.7 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Summit Partners, Volition Capital, Bain Capital Ventures, MassVentures, Highland Capital Partners
  • Research Centers and Universities: MIT, Harvard University, Boston College, Tufts University, Boston University, Northeastern University, Smithsonian Astrophysical Observatory, National Bureau of Economic Research, Broad Institute, Lowell Center for Space Science & Technology, National Emerging Infectious Diseases Laboratories

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account