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Vertex Pharmaceuticals

MSAT Senior Principal Scientist, Data Science and Automation Engineering

Posted 2 Days Ago
Be an Early Applicant
In-Office
Boston, MA
165K-247K Annually
Senior level
In-Office
Boston, MA
165K-247K Annually
Senior level
Lead technical support for data acquisition, analysis, visualization, and automation in gene therapy programs, ensuring compliance with GMP regulations and reporting standards.
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Job Description

Vertex MSAT team is seeking a Senior Principal Data Scientist to join a growing team in support of commercial Cell and Gene Therapy programs. This position will be responsible for leading and providing technical support in alignment with defined program priorities pertaining to data acquisition, analysis, trending, visualization, and reporting.

Key Responsibilities:

  • Identify and develop technical solutions to enable program and company goals.
  • Lead development of data trending visualizations using Statistica and for process parameters
  • Lead the Development of Routine Data Visualization charts and tools
  • Develop scripts for automated reporting of trends and correlations
  • Develop visualization for acknowledged alarm reporting and trending
  • Author SOPs and work instructions to standardize the process of pulling trend reports from TIBCO.
  • Author technical protocols, reports, and other GMP supporting documents.
  • Contribute to developing technical solutions to enable program and company goals.
  • Ability to work within a team and independently
  • Provide regular (weekly) updates towards project goals.

Minimal Requirements:

  • PhD, MS, or BS in relevant science or engineering discipline.
  • PhD with 5+ years, MS with 7+ years, or BS with 9+ years of experience.
  • Significant experience with data software packages including Statistica and Spotfire at a minimum.
  • Experience with cell therapy or large-scale GMP manufacturing for biopharmaceutical manufacturing
  • Experience with designing process monitoring tools to detect OOT/OOE
  • Experience with designing process visualization tools to show process trends
  • Experience with designing automated trend outputs
  • Experience with process characterization and process control strategy preferred.
  • Experience with cGMP regulations/guidance and with regulatory agency inspections preferred.
  • Experience with inline process analytical technologies for assessment of manufacturing performance
  • Experience working and leading projects in a matrixed organization
  • Experience working with external partners (CMOs, vendors, etc.).
  • Excellent communication skills, both written and verbal
  • Ability to travel, nationally and internationally, up to 10 - 15%.
  • Flexibility to work on site a minimum of 3 days per week.

Pay Range:

$164,900 - $247,400

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as: 
1.    Hybrid: work remotely up to two days per week; or select
2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. 
 

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]

Top Skills

Spotfire
Statistica
Tibco
HQ

Vertex Pharmaceuticals Boston, Massachusetts, USA Office

Vertex Pharmaceuticals Inc., 50 Northern Avenue, Boston, MA 02210, US, Boston, MA, United States, 02210

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