Leads Pfizer’s Drug Substance Purification department, overseeing people, resources, production processes, GMP compliance, investigations, scheduling, and continuous improvement. The manager provides technical guidance, manages cross-functional teams, develops direct reports, coordinates maintenance and shutdowns, and supports short- and long-term manufacturing planning. The role requires expertise in pharmaceutical manufacturing, regulatory requirements, people management, communication, and operational decision-making.
Use Your Power for Purpose
Our breakthroughs would not reach patients without our dedicated pharmaceutical manufacturing team. We rely on agile members who understand their crucial role in Pfizer's mission. Patients need colleagues like you who take pride in their work and strive to improve outcomes. Your efforts ensure that patients and physicians have timely access to necessary medicines. Your role will involve overseeing a Drug Substance Purification team and processes. This will involve determining manufacturing methods, procedures, and tooling requirements, as well as designing tools and planning production sequences in line with continuous improvement, Six Sigma, Lean, and other Good Manufacturing Principles (GMP). Your contributions will support Pfizer's mission to prioritize innovation, creativity, and respect for patients, colleagues, and society.
What You Will Achieve
In this role, you will:
Here Is What You Need (Minimum Requirements)
Bonus Points If You Have (Preferred Requirements)
PHYSICAL/MENTAL REQUIREMENTS
Must be able to stand ~1-2 hours at a time.
Inspiring - Motivate and develop self and others to drive the business forward
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
first shift, rotating
Occasional off-shift requirements
OTHER JOB DETAILS
Last Date to Apply for Job: Nov 17, 2026.
Referral Bonus Eligibility: YES
Eligible for Relocation Package: YES
Work Location Assignment: On Premise
The annual base salary for this position ranges from $106,000.00 to $176,600.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .
Manufacturing
Our breakthroughs would not reach patients without our dedicated pharmaceutical manufacturing team. We rely on agile members who understand their crucial role in Pfizer's mission. Patients need colleagues like you who take pride in their work and strive to improve outcomes. Your efforts ensure that patients and physicians have timely access to necessary medicines. Your role will involve overseeing a Drug Substance Purification team and processes. This will involve determining manufacturing methods, procedures, and tooling requirements, as well as designing tools and planning production sequences in line with continuous improvement, Six Sigma, Lean, and other Good Manufacturing Principles (GMP). Your contributions will support Pfizer's mission to prioritize innovation, creativity, and respect for patients, colleagues, and society.
What You Will Achieve
In this role, you will:
- Lead and manage people, technology, and financial resources within the department, ensuring alignment with short-term goals.
- Actively share knowledge and collaborate within and across departments to foster innovation and continuous improvement.
- Identify and implement potential improvements in processes or products, taking calculated risks to develop innovative ideas.
- Solve moderately complex problems within your area of expertise and assist with cross-functional issues, providing technical guidance and oversight.
- Oversee operational activities, manage multiple projects, and ensure compliance with regulations and GMP through effective execution of unit operations.
- Manage the performance of direct reports through goal setting, coaching, mentoring, and ongoing assessment, recognizing and addressing development needs.
- Solicit input, explain complex concepts, and persuade others to adopt a point of view, building alignment across manufacturing assets.
- Own human performance event investigations as Lead Investigator, making autonomous decisions with minor impact and escalating significant decisions.
- Form, lead, and facilitate cross-functional teams to execute key processes, ensuring accountability for the production activities of numerous Pfizer products.
- Assist with short-range and long-range planning, including scheduling operations and staff, and coordinating facilities shutdowns and preventive maintenance.
- Encourage the participation and perspectives of all team members. Effectively listen to and explains difficult issues to reach shared understanding and building alignment. Build alignment across manufacturing assets.
- Provide technical guidance and act as a departmental liaison with primary support groups. Articulate challenges and solutions to technical and non-technical peers and to department management.
- Motivate direct and indirect reports to ensure the function works cross-functionally.
Here Is What You Need (Minimum Requirements)
- Applicant must have a bachelor's degree with at least 4 years of experience; OR a master's degree with at least 2 years of experience; OR a PhD with 0+ years of experience; OR as associate's degree with 8 years of experience; OR a high school diploma (or equivalent) and 10 years of relevant experience
- A robust grasp of industry knowledge and business operations, such as financial basics, enterprise systems like payroll and inventory management
- Proficiency in administrative, managerial, and technical report writing skills
- Effective written and oral communication skills
- Strong computer and presentation capabilities
- Experience in people management
- Knowledge of GMP and regulatory requirements
Bonus Points If You Have (Preferred Requirements)
- Certifications in Continuous Improvement or Project Management
- Familiarity with Local Environmental Health and Safety standards
- Excellent interpersonal and communication skills
- Experience in motivating and developing team members
- Strong leadership and decision-making skills
- Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity. Demonstrated curiosity for exploring how these tools can improve outcomes and understanding of responsible AI practices, including risk management and ethical use
PHYSICAL/MENTAL REQUIREMENTS
Must be able to stand ~1-2 hours at a time.
Inspiring - Motivate and develop self and others to drive the business forward
- Courage - Consistently demonstrate accountability and integrity
- Resilience - Respond to change with agility, optimism and innovation
- Decisive - Manage complexity to make timely informed decisions
- Focus - Develop impactful short- and long-term solutions for our customers and patients
- Connected - collaborate with others to accomplish shared goa
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
first shift, rotating
Occasional off-shift requirements
OTHER JOB DETAILS
Last Date to Apply for Job: Nov 17, 2026.
Referral Bonus Eligibility: YES
Eligible for Relocation Package: YES
Work Location Assignment: On Premise
The annual base salary for this position ranges from $106,000.00 to $176,600.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .
Manufacturing
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