Director - BioPartnering Data Science

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary
The Director of BioPartnering Data Science calls for a technical expert excelling at hands-on work with real-world data, machine learning techniques and programming. Also, strong skills in communication and educating internal and external partners are required.
Caris Discovery not only has access to an extensive multimodal clinical dataset, also it has developed own methods for biomarker and drug target discovery. Combining and mining data from all available sources, building new processes and analysis pipelines are the main focus of this role.
Job Responsibilities

• Apply bioinformatics, data science, molecular biology, and computer science expertise to drive projects developing and refining Caris’ clinico-molecular data products for use by both external partners and internal Caris R&D.

• Communicate with external and internal partners on strategy as well as technical details of Caris data products.

• Educate partners on the use of Caris data products.

• Drive innovation by staying abreast of emerging data science tools, techniques, and best practices, and strategically incorporating them into our data products and workflows.

• Collaborate with research, and bioinformatics scientists to execute projects that translate scientific and clinical questions into analytical workflows, and exercise skill in delivering accurate data processing, quality control, and statistical analysis.

• Act as a subject matter expert on data science, collaborating with internal stakeholders, external partners, and customers to provide technical expertise, foster collaborations, and contribute to the development of joint research projects.

Required Qualifications

• PhD in computational biology, bioinformatics, genomics, or related quantitative fields.

• 10+ years post-PhD work experience, including industry leadership experience.

• Deep experience working with, analyzing, and deriving insight from various types of data (e.g. genomic and clinical data). Expertise in large datasets and raw sequencing outputs, multi-modal data integration, novel algorithm development, and AI/ML applied to large-scale molecular datasets.

• Strong communication skills: A primary responsibility of this role is communication within and across groups at Caris and with external partners at both general and specialist levels. The ability to clearly present nuanced technical material to a variety of stakeholders is critical.

• Enthusiasm for working in a highly collaborative environment and excellent communication skills.

• Strong problem-solving and analytical skills.

• Proven ability to manage time effectively, respond quickly to changing priorities, and adapt within a fast-paced environment.

• Strong programming background (Python, R), cloud experienced (AWS), and familiarity with structured and unstructured omics data platforms. Must be proficient in data visualization and statistics.

• Proficient in Microsoft Office Suite, specifically Word, Excel, Outlook, and general working knowledge of Internet for business use.

Preferred Qualifications

• Experience working in an industry setting.

• Domain experience in oncology.

• Experience working in cloud (preferred) or high-performance computer (HPC) clusters.

Physical Demands

• Will work at a computer most of the time, with some time spent collaborating with subject matter experts and business group leaders either in person or through remote conferencing.

• Visual acuity and analytical skill to distinguish fine detail.

• Must possess ability to sit and/or stand for long periods of time.

Training

• All job specific, safety, and compliance training are assigned based on the job functions associated with this employee.

Other

• This position requires weekly travel into the Caris Cambridge office.

• The position also requires periodic work-related travel (up to 20%) and some evenings, weekends and/or holidays.

• Job may require after-hours response to emergency issues.

Annual Hiring Range

$200,000 - $230,000

Actual compensation offer to candidate may vary from posted hiring range based upon geographic location, work experience, education, and/or skill level. The pay ratio between base pay and target incentive (if applicable) will be finalized at offer.

Description of Benefits

• Highly competitive and inclusive medical, dental and vision coverage options

• Health Savings Account for medical expenses and dependent care expenses

• Flexible Spending Account to pay for certain out-of-pocket expenses

• Paid time off, including: vacation, sick time and holidays

• 401k match and Financial Planning tools

• LTD and STD insurance coverages, as well as voluntary benefit options

• Employee Assistance Program

• Pet Insurance

• Legal Assistance

• Tuition Assistance

Conditions of Employment:  Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.