Your experience includes…
- Ph.D. in Immunology, Pharmacology, Cell Biology, Molecular Biology or related life sciences field with at least 6-8 years of industry or academic experience required
- Extensive experience with animal models of human disease as evidenced by publication record
- Experience establishing human tumor xenograft models
- At least 5 years of leadership experience with a track record of managing teams and laboratory operations
- Experience with models of bone marrow transplantation and / or SCD is desirable
- Experience performing flow cytometric analysis of peripheral blood, bone marrow and other tissues is desirable
You are interested in…
- Establishing humanized mouse models in support of Tessera’s sickle cell disease (SCD) hematopoietic stem cell (HSC) editing program
- Designing and executing in-vivo experiments to study drug product editing efficacy, safety, pharmacokinetics
- Establishing humanized mouse and tumor xenograft models in support of Tessera’s T cell editing program
- Performing IHC, IF, ISH and flow cytometric analysis of blood, tissue and bone marrow samples to monitor the presence and distribution of edited cells
- Designing and executing nonhuman primate studies in support of our HSC and T cell editing programs
- Designing and executing nonclinical studies to support IND applications for advancing product candidates
- Authoring, updating and maintaining IACUC protocols for our in-vivo studies
- Managing and mentoring a group of junior in-vivo scientific staff
- Staying abreast of the current relevant medical literature and contributing your expert opinions to scientific discussions during cross functional project team meetings
- Contributing novel ideas about how we can apply our core technologies to diseases with unmet needs
About you:
You are a highly motivated in vivo/ex vivo scientist with robust experience in hematopoietic stem cell biology and/or cancer immunology. You have experience designing and executing studies to help drive early discovery research and are interested in utilizing Tessera’s Gene Writers to edit hematopoietic stem cells and immune cells in vivo.
Tessera leaders are empathetic and transparent coaches with a strong sense of integrity. They are committed to the growth and development of their teams, the organization and themselves.
Leadership Structure:
All inquiries regarding the posted position should be directed to the Talent Partner (see below). Interested individuals must apply directly to be considered for the opening.
James Rottman, DVM, PHD, DACVP - Head of Pharmacology
Jim is a veterinary pathologist with 30+ years of experience in the biotech industry focused in pharmacology, discovery pathology and investigative toxicology. He holds specific expertise in immunopathology and the development of immunotherapeutics and specializes in the integration/ interpretation of complex clinical, histologic and molecular data.
Jim enjoys sharing his passion for pathology and immunology with veterinary students. He is a former US Army officer and Desert Shield/Storm veteran and a current instructor pilot.
Meet our Leadership Team and Board of Directors
Meet your Talent Partner:
Narissa Furtado-Cordeiro - Manager, Talent Acquisition
Narissa joined the Biotechnology industry shortly after graduating with her BS in Marketing from Franklin Pierce University. She is currently pursuing an MS in Legal Studies from Northeastern University School of Law while working full time as a Manager in Talent Acquisition at Tessera. She is passionate about helping individuals find a fulfilling opportunity while considering their interests, aspirations and technical skills. Narissa lives in Northern Vermont and enjoys spending time outdoors with her husband, three-year-old daughter and German Shepherd.
Tessera offers a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits currently include group medical, vision and dental coverage, group life and disability insurance, 401(k) with company contribution, tuition reimbursement, and much more.
Company Summary:
Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.
More about Tessera Therapeutics:
Tessera is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, marital status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. Tessera provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with Tessera regarding a reasonable accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied, please contact the recruiter or [email protected]
Recruitment & Staffing Agencies: Tessera Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Tessera Therapeutics or its employees is strictly prohibited unless contacted directly by Tessera Therapeutics’ internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Tessera Therapeutics, and Tessera Therapeutics will not owe any referral or other fees with respect thereto.
Top Skills
Tessera Therapeutics Cambridge, Massachusetts, USA Office
Cambridge, Cambridge, MA, United States, 02139
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