Top Remote Senior Level Machine Learning Engineer Jobs in Boston, MA

Leads the architecture and development of production-grade Generative AI, RAG, agentic, and intelligent automation solutions. Builds LLM applications, APIs, retrieval systems, evaluation frameworks, and cloud-based AI workloads using Python and modern data platforms. Establishes practices for testing, monitoring, governance, security, reliability, and responsible AI. Partners with clinical, operational, product, and business stakeholders while mentoring engineers and evaluating emerging technologies.

Leads the architecture, development, deployment, and optimization of large-scale AI systems, including foundation model training, LLM inference, agentic workflows, similarity search, guardrails, evaluation, governance, and observability. Establishes enterprise AI architecture, performance and safety standards, and multi-year platform strategies. Partners across engineering, research, product, and program management while mentoring technical leaders and driving responsible AI adoption.

Build scalable systems and machine learning models that transform satellite imagery into labeled geospatial data and production computer vision products. Responsibilities include developing data and annotation pipelines, tracking lineage and versioning, deploying inference services, evaluating models, supporting cloud infrastructure, and improving labeling workflows. The role requires strong Python, cloud, containerization, CI/CD, infrastructure-as-code, production support, and deep learning expertise, with preferred experience in GCP, Vertex AI, spatial databases, and satellite imagery.

Design, build, and support high-throughput, low-latency LLM inference and data pipelines; collaborate with data scientists to post-train and evaluate models; implement scalable, production-ready systems with strong testing, monitoring, and performance focus; mentor engineers and iterate on architecture, reliability, and user-facing AI applications.

Lead end-to-end LLM inference performance across serving systems, models, GPU hardware, and workloads. Define rigorous benchmarks, diagnose bottlenecks from scheduling through kernels and interconnects, optimize single- and multi-node deployments, and deliver production-ready runtimes and configurations. Collaborate with product and infrastructure teams, evaluate inference technologies, and implement runtime fixes. The role requires strong Python engineering, production experience with serving engines such as vLLM or SGLang, GPU profiling, and knowledge of modern inference optimization techniques.

Build and deploy production machine learning systems that optimize Samsara’s global hardware supply chain. Responsibilities include demand, inventory, lead-time, spend, and supplier-risk forecasting; anomaly detection; feature engineering and ETL; real-time inference; MLOps; data infrastructure improvements; governance; and model monitoring. The role defines the AI transformation roadmap, partners with executive and cross-functional stakeholders, mentors scientists, and drives adoption of AI-enabled operational workflows.

Own the reliability and quality of an AI copilot for a trading platform. Build evaluation frameworks, benchmarks, quality gates, monitoring, incident response, and model improvement workflows. Partner with engineering and product to create safe, auditable tool interactions and improve assistant behavior. Develop domain expertise in trading, risk, margin, execution, and portfolio reasoning while operating across model, backend, and frontend systems.

Develop and operate production ML and AI systems powering patient experiences such as matching, ranking, recommendations, onboarding, and personalization. Build reusable ML infrastructure, pipelines, evaluation, observability, and model-serving capabilities. Provide technical leadership across the ML lifecycle, guide architecture, evaluate custom versus foundation-model approaches, and partner with ML and Patient Engineering teams to deliver reliable, scalable AI products.

Leads and mentors Applied Scientists developing, evaluating, and deploying machine learning and language-model solutions for healthcare workflows. Translates clinical and business problems into scalable AI systems, applies rigorous statistical methods and experimentation, partners with engineering and cross-functional stakeholders, and ensures models are reliable, reproducible, and safe. The role also contributes hands-on technical work, recruiting, onboarding, and team development.

Develop and maintain production machine learning models, build scalable training and serving technologies, optimize real-time and batch ML pipelines, and monitor model performance and drift. The role involves deep neural networks, recommendation systems, automated retraining, ML research, engineering excellence, and communicating technical concepts to diverse audiences. Candidates need 6+ years of industry ML experience, strong coding skills, and experience deploying neural networks at scale.