Vice President, US Obesity Medical Lead

ROLE SUMMARY
The Vice President, US Medical Affairs Obesity Lead, is an integral member of the US Medical Leadership Team and reports to the Head of US Medical Affairs. The incumbent will lead a team and develop the vision and strategic direction to yield the highest level of medical impact for the US Obesity franchise in US Medical Affairs. The position has broad impact throughout the organization and requires obesity experience with an understanding of pharmaceutical business operations, products, strategic thinking skills, leadership ability, and strong knowledge of the stakeholder community and market dynamics. With exceptional obesity portfolio knowledge this will contribute to the global obesity portfolio strategy. The leader is expected to build and maintain strong opinion leader relationships engaging in external collaborations to gain insight and to inform clinical development and life cycle plans.
The Vice President, US Medical Affairs Obesity Lead, will work with cross functional partners to leverage operational excellence for the US to ensure timely delivery of major clinical trials, IIRs, RWE and core data dissemination activities. Accountable to build the US medical budget and to execute with excellence and highest levels of integrity and compliance. The US Obesity Medical Lead will also facilitate and manage the team's appropriate internal information sharing and coordination (e.g., with relevant U.S. commercial teams) to ensure that they are conducted in compliance with both Pfizer and external policies, guidelines, and regulations. The Lead brings their leadership skills, technical expertise, and an in-depth understanding of medicine development to bear on all activities while putting the patient first within the spectrum of the Pfizer Core Values and Behaviors.
ROLE RESPONSIBILITIES
The Obesity Medical lead is responsible for leading the US Medical Obesity team comprised of Brand Medical teams across the Obesity portfolio. The incumbent will partner closely with the Internal Medicine (IM) category lead, Field Medical organizations, Global Medical, other Regional Heads, publications, Medical Excellence, Outcomes & Evidence, Clinical Sciences, PRD and the Commercial lead:

• To ensure a world class team with exceptional understanding of the US, one of the most important global markets
• To lead the US medical strategy and ensure US market medical needs are appropriately represented from data generation (in partnership with PRD, as appropriate) to evidence dissemination and education of key stakeholders across the pipeline, in-line and late-stage development portfolio
• Maintain exceptional peer and KOL relationships, and a superb understanding of the obesity US health care ecosystem and the access environment
• Maintains strong working relationships and communications with Pfizer commercial lines in the region and headquarters
• Serves as a member of the US Primary Care Leadership Team
• Maintains strong working relationships with necessary platform functions such as Legal, Compliance and People Experience.

Duties and Responsibilities may be delegated as appropriate, though the US Obesity Medical Lead retains accountability. These include but are not limited to:

• Engage on peer basis with medical directors of independent networks and other healthcare providing entities to develop mutually beneficial solutions enhancing patient care
• Chairs or leads the US Medical Affairs Team, as appropriate, which is the Medical governance body for the portfolio/assets
• Represents US medical affairs at the relevant asset team and/or other appropriate teams and committees across the enterprise
• Takes on leadership role in development of US evidence generation plan and partners with Global on the Integrated Evidence Plan
• Proactively incorporates patients' & physicians' voice in the development strategy across the obesity portfolio, to provide medicines meeting their needs, as well as the needs of customers, including payers
• Serves as subject matter expert for portfolio asset(s) and ensures consistency of interpretation and communication of data, both internally and externally, by partnering with critical stakeholders within PRD or the parallel customer facing organizations to drive uniform consensus and alignment around the medical and scientific interpretation of the asset data set
• Ensures US aligned medical input into the US commercial strategy and its implementation
• Leads the management of US issues and assists and supports uniform medical needed
• Delivers US medical activities in support of the asset operating plan within time, cost and quality parameters; responsible for managing resources required to deliver such activities
• Leads the planning of timely, high-quality execution of US medical tactics and lifecycle plans
• Understands and facilitates all US medical activities in support of the portfolio operating plan
• Provides leading edge knowledge and an ability to apply technical and medical expertise in leading the strategic direction of in line and business portfolio enhancing organizational success by grounding decisions in sound medical insights
• Works in collaboration with Marketing/Commercial Development, Clinical, and Medical Teams providing strategic direction in the drug development cycle and disease concept
• Participates in Rapid Response Team to provide medical expertise on current issues that potentially interface with the public and in regulatory matters
• Engages and leads interactions with clinical and research leaders (experts) including academicians, clinical physicians, medical directors, directors of pharmacy and other health care professionals aligned with brand objectives
• Proactively guides brand objectives and generates strategic medical solutions to business challenges
• Proactively identify and address potential medical issues and ensure implementation of risk-management strategies in collaboration with team partners
• Assesses safety and regulatory aspects with partners in these functional lines, including participation in safety and labeling working groups and potential interactions with the regulatory agency related to both promotional activities and labeling
• Considers strategic implications for medicine's benefit-risk profile and relevant medical /scientific data that potentially interface with the public, including regulatory, in a manner customized to promote effective understanding for each specific audience (e.g. medical, marketing, sales, regulatory, etc.)
• Provides medical expertise in the medical/scientific assessment of potential business development activities and pre-proof of concept compounds within Pfizer Research Unit, as applicable
• Influences decisions in the organization of external meetings including advisory boards, congress, and symposium as appropriate and seeking active feedback for continuous improvement
• Sets the strategy and provides guidance to or leads Publication Subcommittee (or regional efforts) including concept, plan, author and agency liaison and final check in the Publication Subcommittee review process
• Help establish an environment encouraging coaching among team members, including supporting colleagues at meetings, post meetings ad hoc discussion with multiple colleagues about how they can improve their performance in meetings directly related to previous meeting

BASIC QUALIFICATIONS
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

• MD, Pharm D, PhD, or Equivalent Doctorate degree required
• More than 10 years with PharmD/PHD or more than 9 years with MD in the medical affairs function in the pharmaceutical industry with broad experience including drug development, regulatory interactions, issue management, and business experience to have a thorough understanding of the processes associated with Medical Affairs.
• Expert in Obesity market dynamics, current treatment landscape strongly preferred
• Experience with patient care, especially in specific therapeutic area preferred
• Deep understanding of HCP informational needs and what is required to support these needs
• Scientific translational research background and ability to understand, interpret, and communicate scientific literature
• In-depth understanding and experience with study methodology, protocol design, safety evaluation, and data analysis
• Proactive, pragmatic, flexible person with excellent leadership qualities, strategic thinking, communication & presentation skills
• An ability to lead and manage in a matrixed structure and in a collaborative team environment.
• Extensive knowledge of patterns of medical practice and healthcare delivery and current and evolving landscape will be required.
• An ability to lead and manage in a matrixed structure and in a collaborative team environment
• Clear networking and alliance building capabilities with an ability to influence and develop others and navigate internal processes.
• Highly motivated with demonstrated track record of high performance and producing outstanding results.
• Proficiency in building and managing relationships with stakeholders, including Senior Leaders, ensuring appropriate stakeholders are included in deliberations and decision-making
• Management and leadership skills, with the ability to lead matrixed, cross-functional work teams
• Proven ability to facilitate open discussion and debate among key stakeholders and build internal and external relationships through partnering, anticipating needs, fulfilling expectations.
• Demonstrated entrepreneurship mindset, accountability, agility and focus on action and implementation
• Demonstrated record of sound judgment and intelligent decision-making
• Strong interpersonal skills to quickly build rapport and credibility with Pfizer leaders and key external stakeholders
• Ability to evaluate budget requests
• Strong people leadership and management
• Experience working in an alliance with another pharmaceutical company a plus.
• Capable of comprehending and communicating in a clear, concise manner a large amount of scientific information.
• Ability to lead strategy development.
• An ability to be flexible and to be innovative.
• International experience a plus, Regulatory experience a plus.
• Fluency in written and spoken English required, with excellent communication skills.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Travel: approximately ~20%
This is a hybrid role requiring candidates to live within commuting distance and work on-site an average of 2.5 days per week or more as needed.
Other Job Details:
Last Date to Apply for Job: February 20th, 2026
Additional Location Information: New York, NY; Cambridge, MA
Eligible for Relocation Package: No
#LI-PFE
The annual base salary for this position ranges from $300,100.00 to $467,400.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 30.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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