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Roche

Transporter Scientist, ADME Chapter, PS, pRED (Temporary position for 2 years)

Reposted 2 Days Ago
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In-Office
Basel, Basel-Stadt
Senior level
In-Office
Basel, Basel-Stadt
Senior level
The ADME Scientist will develop and validate in vitro models to enhance drug transport studies, ensuring compliance with regulatory standards and collaborating with cross-functional teams.
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At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

In Roche´s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicine. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

pRED's Pharmaceutical Sciences (PS) group enables discovery and development of safe and effective therapeutics at optimal doses in relevant populations with a vision to power translation, continuously improve the accuracy of our predictions and accelerate the development of tomorrow's medicines. PS supports discovery and development across the whole value chain from target assessment to on-market and beyond.

This position is located in ADME, a chapter within Global Pharmaceutical Sciences, where the fate of new chemical entities and biologics is a primary focus. The ADME Chapter works throughout all stages of compound development, from lead optimization to candidate selection, all clinical development phases to filing of new drug applications. We closely collaborate with our therapeutic areas and functions to convert hypotheses into innovative therapeutics.

The Opportunity

 As an ADME Scientist specializing in drug transport, your mission is to join our laboratory efforts in developing and validating cutting-edge in vitro models. You will play a pivotal role in advancing the study of transport and permeability properties of new drug candidates, contributing to the acceleration of drug development processes.

  • You independently plan, analyze, report and present study results related to transporter-mediated clearance, drug-drug interactions and permeability to internal and external stakeholders, ensuring data integrity and relevance.

  • You drive the development, characterization and validation of innovative in vitro models to study drug transport and permeability and enhance the accuracy and efficiency of in vitro assessments.

  • You serve as a subject matter expert, engaging with cross-functional teams to discuss results and coordinate studies conducted internally and with external partners.

  • You maintain lab infrastructure, materials and analytical instruments.

  • You ensure all experimental procedures and results comply with regulatory standards. You prepare detailed reports and documentation to support regulatory submissions and intellectual property filings.

  • You continuously learn and improve by engaging in ongoing professional development to maintain expertise in the latest scientific advancements. You foster a culture of innovation and continuous improvement within the team.

Please note this position is temporary for 2 years.

Who you are
  • You hold a PhD in pharmaceutical sciences or a related relevant discipline with in-depth practical experience (preferably industrial) with in vitro ADME studies, focus on drug transport preferred.

  • You are familiar with lab automation and common digital tools for experimental planning, FAIR data capturing, evaluation and reporting in databases and reports.

  • You have a successful background in developing and applying cellular systems for in vitro ADME methodologies. You are committed to working in a team and are focused on driving the portfolio forward with the best approaches available.

  • You have a strong ability to communicate effectively in a fast-paced and dynamic environment, coupled with excellent interpersonal skills.

Unwavering focus, collaborative teamwork and exceptional delivery are key behaviours that drive our mission of doing now what patients need next. Together, we can be transformative.

If you are passionate about contributing to a committed team and have the dedication to partnership and innovation, Roche is the place for you! Every role at Roche plays a part in making a difference in patients’ lives. 

Apply now and join us in making an impact!

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.


Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.

Top Skills

Databases
Digital Tools
In Vitro Models
Lab Automation

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