Landmark Bio is seeking an experienced, hands-on IT professional to oversee end-user technology, infrastructure, and IT operations supporting a regulated biotech environment. This role is responsible for maintaining reliable, secure, and scalable systems that support day-to-day business and laboratory operations.
The Senior Manager, IT will lead IT operations, manage vendors and managed service providers, and partner with internal stakeholders to ensure technology solutions support business needs while maintaining compliance with regulatory and security requirements.
This role requires strong technical depth, operational discipline, and the ability to work across multiple functions in a fast-moving organization.
Responsibilities
Maintain and support on-premise and cloud-hosted infrastructure, end-user devices, networking, and business applications
Ensure high availability, performance, and security of IT systems
Support regulated GxP laboratory and manufacturing environments
Manage user accounts, access control, device provisioning, and software deployment
Oversee backup, disaster recovery, and monitoring systems
Microsoft 365, SharePoint, Teams, Office
Windows Server / Windows 10/11
Meraki network / Palo Alto firewall / VPN
FreshService, CyberReason, Kaseya, IT Glue, Autotask, Rocket Cyber, BullPhish, RMM, Spanning, Unitrends
Building security and monitoring systems
End-user hardware, printers, and conference room AV
Business systems including Smartsheet, Veeva, SAP, DocuSign, Okta, Adobe
Lab instrument user accounts and software installs
Ensure timely and effective IT support for employees and laboratory users
Improve reliability, usability, and performance of end-user systems
Partner with business teams to evaluate and implement new applications
Support onboarding, offboarding, and equipment lifecycle management
Coordinate with external IT vendors and service providers
Monitor performance, costs, and service quality
Assist with contract renewals, budgeting, and vendor selection
Maintain IT policies, procedures, and documentation
Support CSA / SDLC / GxP / audit readiness activities
Ensure systems meet cybersecurity and data protection standards
Support validation and regulated system controls where required
Lead small to mid-size IT projects and system implementations
Identify opportunities to improve efficiency, automation, and reliability
Support site expansion, lab build-out, and new system deployments
1. IT Operations & Infrastructure
Platforms include:
2. User Support & Experience
3. Vendor & Managed Service Provider Management
4. Compliance & Security
5. Projects & Continuous Improvement
Qualifications
Bachelor’s degree in Information Technology, Computer Science, or related field
8+ years of IT experience, preferably in biotech, pharma, or regulated industry
Strong hands-on experience with end-user systems, infrastructure, and networking
Experience supporting cloud, SaaS, and on-premise environments
Experience working in GxP / regulated / manufacturing / lab environments preferred
Experience managing vendors and managed service providers
Strong troubleshooting and problem-solving skills
Ability to work independently in a small, fast-paced organization
Landmark Bio Watertown, Massachusetts, USA Office
Our company is located in Watertown's Arsenal Yards--next door to restaurants, bars, and entertainment. We are also directly across from the Charles River with plenty of walking trails.
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