Pfizer Logo

Pfizer

Senior Scientist

Posted An Hour Ago
Be an Early Applicant
In-Office
Cambridge, MA, USA
94K-156K Annually
Senior level
In-Office
Cambridge, MA, USA
94K-156K Annually
Senior level
Conduct drug discovery research in cardiovascular biology, focusing on identifying and validating therapeutic targets and biomarkers related to atherosclerosis. Design and execute cellular, molecular, imaging, ex vivo, and animal studies; analyze data; collaborate with internal and academic scientists; communicate findings through publications and presentations; uphold scientific and regulatory standards; and mentor junior scientists.
The summary above was generated by AI
COMPANY OVERVIEW
At Pfizer, our purpose is to deliver breakthroughs that transform patients' lives. Central to this mission is our Research and Development organization, which is dedicated to translating advanced science and innovative technologies into impactful therapies and vaccines. In this role, you will be at the forefront of this effort, helping ensure that daily activities align with Pfizer's unwavering commitment to quality. Your work will accelerate the delivery of best-in-class medicines to patients globally and support Pfizer's commitment to making a meaningful difference in healthcare.
ROLE SUMMARY
As a member of the Cardiovascular Discovery Biology team, the Senior Scientist will play a pivotal role in the drug discovery process, from ideation and hypothesis generation to the identification and validation of therapeutic targets and disease-relevant biomarkers.
This individual will contribute to experimental strategy and execution while working closely with scientists across disciplines. Expertise in atherosclerosis biology is essential, and familiarity with different aspects of cardiovascular disease is highly desirable. Daily interactions will take place within a dynamic and supportive environment of innovative scientists. Success in this role requires strong self-motivation, excellent communication and interpersonal skills, and the ability to influence and collaborate effectively in a team setting.
ROLE RESPONSIBILITIES
  • Apply scientific expertise and creative thinking to develop strategies for identifying and validating therapeutic targets aligned with IMRU priorities.
  • Apply state-of-the-art cellular, molecular, and animal model techniques to investigate mechanisms of atherosclerotic plaque progression, including data analysis and interpretation.
  • Stay current with cutting-edge developments in preclinical and translational science and integrate relevant advances into portfolio programs.
  • Build and maintain collaborations with academic partners and internal Pfizer scientists.
  • Communicate research findings through peer-reviewed publications, scientific presentations, and internal leadership briefings.
  • Uphold the highest standards of scientific integrity, quality, and compliance with regulatory and ethical guidelines.
  • Support the development of junior scientists through mentorship and collaborative engagement.

QUALIFICATIONS
Basic Qualifications:
  • Ph.D. in Molecular Biology, Biotechnology, Cardiovascular Biology, or related fields.
  • A minimum of 1-2 years of postdoctoral or relevant industry experience in drug discovery or translational research.
  • Demonstrated expertise in cardiovascular or atherosclerosis disease biology.
  • Proficiency in vitro and in vivo cardiovascular-atherosclerotic systems, including foam-cell and vascular-cell assays, molecular biology, high-content imaging, ex vivo approaches, and rodent models of atherosclerosis.
  • Strong analytical and problem-solving capabilities, supported by a track record of impactful scientific contributions.
  • Proven ability to work independently and collaboratively within fast-paced-interdisciplinary research teams.
  • Capacity to manage multiple projects simultaneously with scientific rigor and adaptability.
  • Excellent written and verbal communication skills, with the ability to present complex scientific concepts effectively.

Preferred Qualifications:
  • Prior experience in drug discovery is preferred but not required.
  • Experience leveraging human data sources, such as genetic and multi-omics to support discovery and development activities is a plus.
  • Experience with neurovascular diseases is a plus.

Adhere to safe work practices and procedures such as aseptic gowning
Relocation support may be available
Work Location Assignment: On Premise
#LI-PFE
The annual base salary for this position ranges from $93,600.00 to $156,000.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .
Research and Development

Similar Jobs at Pfizer

2 Days Ago
In-Office
69K-114K Annually
Senior level
69K-114K Annually
Senior level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
Develop mammalian cell culture processes and build software for bioprocess automation and digitization. Translate process knowledge into control schemes, alarms, user interfaces, instrument integrations, and data infrastructure. Design and troubleshoot scale-down bioreactor experiments, support deployed applications, manage code and testing, and serve as a technical expert for bioprocess instrumentation and platform integration.
Top Skills: AmbrDeltavDockerElasticsearchGitGithub ActionsKepwareLinuxModbusOpc UaPostgresRest ApisRockwellSiemensSnowflakeStreamlit
9 Days Ago
In-Office
Cambridge, MA, USA
69K-114K Annually
Senior level
69K-114K Annually
Senior level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
Performs computational genomics work including sequencing data processing, quality assessment, reproducible bioinformatics analysis, visualization, troubleshooting, and biological interpretation across single-cell, spatial, bulk, and multiomic datasets. Supports experimental design, workflow benchmarking, technical documentation, training, and data integrity. Conducts a smaller wet-lab component involving sample preparation, tissue and cell processing, nucleic acid extraction, library preparation, sequencing, and assay execution for drug discovery and translational research.
Top Skills: Ai-Enabled Bioinformatics ToolsBioinformatics WorkflowsBiomniBulk Rna SequencingClaude ScienceCommand-Line ToolsComputational Biology WorkflowsElectronic Lab NotebooksEpigenomics AssaysImmune Repertoire SequencingMultiomicsNotebooksPythonRSequencing Library PreparationSingle-Cell Rna SequencingSingle-Nucleus Rna SequencingSpatial TranscriptomicsTargeted SequencingTooluniverseVersion-Controlled Workflows
10 Days Ago
In-Office
Cambridge, MA, USA
69K-114K Annually
Senior level
69K-114K Annually
Senior level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
Performs computational genomics and bioinformatics analysis of single-cell, spatial, bulk, and multiomic datasets, including data processing, quality assessment, visualization, reproducible reporting, and biological interpretation. Supports genomic assay evaluation, experimental design, workflow qualification, and technical documentation. Conducts limited wet-lab work involving sample preparation, tissue and nuclei isolation, nucleic acid extraction, library preparation, sequencing, and quality control. Also assists with training, presentations, and maintaining compliant data-integrity records.
Top Skills: BiomniBulk Rna SequencingClaude ScienceCommand-Line ToolsComputational NotebooksEpigenomics AssaysImmune Repertoire SequencingMultiomicsPythonRSingle-Cell Rna SequencingSingle-Nucleus Rna SequencingSpatial TranscriptomicsTargeted SequencingTooluniverseVersion-Controlled Workflows

What you need to know about the Boston Tech Scene

Boston is a powerhouse for technology innovation thanks to world-class research universities like MIT and Harvard and a robust pipeline of venture capital investment. Host to the first telephone call and one of the first general-purpose computers ever put into use, Boston is now a hub for biotechnology, robotics and artificial intelligence — though it’s also home to several B2B software giants. So it’s no surprise that the city consistently ranks among the greatest startup ecosystems in the world.

Key Facts About Boston Tech

  • Number of Tech Workers: 269,000; 9.4% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Thermo Fisher Scientific, Toast, Klaviyo, HubSpot, DraftKings
  • Key Industries: Artificial intelligence, biotechnology, robotics, software, aerospace
  • Funding Landscape: $15.7 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Summit Partners, Volition Capital, Bain Capital Ventures, MassVentures, Highland Capital Partners
  • Research Centers and Universities: MIT, Harvard University, Boston College, Tufts University, Boston University, Northeastern University, Smithsonian Astrophysical Observatory, National Bureau of Economic Research, Broad Institute, Lowell Center for Space Science & Technology, National Emerging Infectious Diseases Laboratories

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account