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Lila Sciences

Senior Research Associate, LNP Formulations

Posted Yesterday
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In-Office
Cambridge, MA
72K-106K Annually
Senior level
Easy Apply
In-Office
Cambridge, MA
72K-106K Annually
Senior level
Collaborate on LNP formulations, develop automated workflows, and conduct bioanalytical assays while supporting interdisciplinary research teams.
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Your Impact at Lila

We are seeking a (Senior) Research Associate to join our Physical Sciences team. This role will focus on assisting in the design and development of advanced microfluidic platforms for the controlled synthesis and characterization of lipid nanoparticles (LNPs) and other nanocarriers. The ideal candidate will have hands-on expertise in various LNP formulation techniques, downstream characterization assays, and experience with automation technologies. Your work will bridge the physical sciences and bioanalytical domains, enabling high-throughput experimentation integrated with real-time analytics. This position will work closely with others across the chemistry, biology, machine learning, and data science teams to help establish next-generation tools for therapeutic development and delivery.

What You'll Be Building

  • Design and execute LNP formulations using various microfluidic systems, with a focus on high throughput screening to select and optimize lead formulations.
  • Develop and run downstream characterization assays for nucleic acid therapeutics (including DLS, ribogreen assay, TNS assay, etc.)
  • Assist in the design of, and routinely execute, automated high-throughput experimentation workflows using microfluidic platforms and robotics to synthesize nanoparticles.
  • Collaborate with chemists, material scientists, engineers, and data scientists to document systems, share insights, and refine best practices in autonomous flow chemistry.
  • Write, implement, and maintain Standard Operating Procedures (SOPs) for both existing and new lab processes.

What You’ll Need to Succeed

  • MSc in Chemical Engineering, Biomedical Engineering, Pharmaceutical Sciences, or a related field with 3+ years, or BSc with 5+ years, of hands-on experience in microfluidic device development and LNP synthesis, or related experience. Industry experience strongly preferred.
  • Strong experience with lipid nanoparticle formulations, with an emphasis on high throughput production.
  • Strong working knowledge of bioanalytical techniques (e.g., DLS, fluorescence spectroscopy, electrophoresis, in vitro assays).
  • Strong data analysis skills and ability to interpret results, using learnings to iterate on experimental designs.
  • Excellent troubleshooting, communication and collaboration skills, with a proven ability to work effectively across interdisciplinary teams.

Bonus Points For

  • Familiarity with scale up considerations for nanoparticle manufacturing.
  • Experience with drug delivery systems beyond standard LNPs, including targeted nanoparticles (antibody/ligand decoration, evaluating different linker chemistries, etc.)
  • Experience using automation instruments to perform routine lab work.
  • Familiarity with digital systems and data pipelines used in high-throughput environments.

About Lila

Lila Sciences is the world’s first scientific superintelligence platform and autonomous lab for life, chemistry, and materials science.  We are pioneering a new age of boundless discovery by building the capabilities to apply AI to every aspect of the scientific method.  We are introducing scientific superintelligence to solve humankind's greatest challenges, enabling scientists to bring forth solutions in human health, climate, and sustainability at a pace and scale never experienced before. Learn more about this mission at  www.lila.ai

If this sounds like an environment you’d love to work in, even if you only have some of the experience listed below, we encourage you to apply.

Compensation

We expect the base salary for this role to fall between $72,000–$106,000 USD per year, along with bonus potential and generous early equity. The final offer will reflect your unique background, expertise, and impact.

We’re All In

Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.

A Note to Agencies

Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.

Top Skills

Automation Technologies
Bioanalytical Techniques
Data Analysis
Lipid Nanoparticles(Lnps)
Microfluidic Platforms
Robotics

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