Bristol Myers Squibb Logo

Bristol Myers Squibb

Senior Principal Scientist, Lead Development Biomarker Studies,Translational Development

Reposted 10 Days Ago
Be an Early Applicant
3 Locations
Senior level
3 Locations
Senior level
The Senior Principal Scientist will lead development and execution of biomarker strategies for clinical programs, engage with cross-functional teams, and support regulatory submissions in hematology.
The summary above was generated by AI

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

The Senior Principal Scientist role will be responsible for development and execution of myeloma asset centric translational strategies in hematology for assigned programs. Key responsibilities of this role are to act as a lead scientist to deliver and implement biomarker strategies for clinical programs, develop reports and publications on preclinical and translational data generated to support asset development and contribute to regulatory submissions. This individual will work on cross-functional project teams to drive execution of translational/biomarker plans working with laboratory and disease scientists and BMS members from clinical, medical, commercial, regulatory and diagnostics as well as engage external academic collaborators/Key opinion leaders (KOLs). This position can be located in Summit, NJ or Princeton/LVL, NJ or Cambridge Crossing, MA

Professional Skills:

  • In-depth understanding of cancer biology/hematology with knowledge of current and evolving clinical landscape and competitive scenarios
  • Strong scientific background with understanding of clinical, translational, and mechanistic data with proven track record of publications
  • Understanding of early or late-stage drug and translational development process; including experience with implementing a biomarker strategy
  • Clinical protocol authoring and review of regulatory documents.
  • Working knowledge of technological platforms covering biomarker measures including but not limited to genomics, gene expression, immune profiling, and flow cytometry.
  • Excellent data analysis and problem solving skills
  • Exceptional verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications/reviews, scientific presentations and regulatory submissions (INDs/NDAs) with ability to synthesize complex scientific concepts into simple communication points
  • Proven scientific/project leadership expertise and experience working in global teams and managing people/projects

Responsibilities:

  • Oversees biomarker execution in clinical trials and supports biomarker sampling and subsequent data analysis
  • Leads the development of asset specific translational goals and objectives for the Hematology Translational Medicine group
  • Represents Translational Medicine on cross-functional strategy and global project teams
  • Supports regulatory submissions, regulatory interactions, writes translational sections for regulatory responses and answers to regulatory queries for the TM group
  • Participate/present data at scientific advisory boards to support drug programs/projects
  • Communicates regularly and prepares and makes presentations within the department and externally as required
  • Responsible for selection and delivery of pharmacodynamic and biomarker assays including assessing the need and applicability for companion/complementary diagnostics for asset programs
  • May perform advisory and mentoring role for junior scientists

Qualifications:

  • PhD in Hematology/Oncology or related field with min 6 years in industry and academic setting
  • Track record in drug discovery/development in large or small biotech/pharmaceutical companies, leading translational/biomarker studies or innovative efforts to deploy technologies and assays for enhanced translational capabilities or similar skill sets in academia
  • Experience with translational/biomarker strategies for early or late stage clinical trials or investigator sponsored trials in academia

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Top Skills

Biomarker Strategies
Flow Cytometry
Gene Expression
Genomics
Immune Profiling

Similar Jobs

2 Days Ago
Remote
Hybrid
Location, WV, USA
100K-125K Annually
Mid level
100K-125K Annually
Mid level
Artificial Intelligence • Fintech • Information Technology • Machine Learning • Financial Services
The Senior Data Analyst will analyze financial statements, support AI model training, and collaborate with teams for data extraction in private markets.
Top Skills: AIData ExtractionDocument MarkupFinancial Analysis
Yesterday
Remote
Hybrid
38 Locations
110K-180K Annually
Mid level
110K-180K Annually
Mid level
Cloud • Computer Vision • Information Technology • Sales • Security • Cybersecurity
The role involves ensuring the reliability of data systems through building ETL processes, automated quality checks, and managing data integrity and reporting.
Top Skills: Apache AirflowSparkApache SupersetETLJIRAMySQLNumpyPandasPostgresPythonSQLSqlalchemyTableau
2 Days Ago
Easy Apply
Morgantown, WV, USA
Easy Apply
40K-175K
Junior
40K-175K
Junior
Edtech • Fintech • Sports
Account Executives drive sales performance by establishing relationships and executing territory plans, managing customer records, and achieving sales targets across schools and organizations.
Top Skills: Hubspot

What you need to know about the Boston Tech Scene

Boston is a powerhouse for technology innovation thanks to world-class research universities like MIT and Harvard and a robust pipeline of venture capital investment. Host to the first telephone call and one of the first general-purpose computers ever put into use, Boston is now a hub for biotechnology, robotics and artificial intelligence — though it’s also home to several B2B software giants. So it’s no surprise that the city consistently ranks among the greatest startup ecosystems in the world.

Key Facts About Boston Tech

  • Number of Tech Workers: 269,000; 9.4% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Thermo Fisher Scientific, Toast, Klaviyo, HubSpot, DraftKings
  • Key Industries: Artificial intelligence, biotechnology, robotics, software, aerospace
  • Funding Landscape: $15.7 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Summit Partners, Volition Capital, Bain Capital Ventures, MassVentures, Highland Capital Partners
  • Research Centers and Universities: MIT, Harvard University, Boston College, Tufts University, Boston University, Northeastern University, Smithsonian Astrophysical Observatory, National Bureau of Economic Research, Broad Institute, Lowell Center for Space Science & Technology, National Emerging Infectious Diseases Laboratories

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account