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Flagship Pioneering

Senior Backend Engineer

Posted 7 Days Ago
In-Office
Cambridge, MA
50K-160K
Senior level
In-Office
Cambridge, MA
50K-160K
Senior level
As a Senior Backend Engineer, you'll design high-performance APIs, manage data systems, and optimize backend services for an AI-driven scientific platform, collaborating with cross-functional teams.
The summary above was generated by AI

🚀 About Lila Sciences

Lila Sciences is the world’s first scientific superintelligence platform and autonomous lab for life, chemistry, and materials science.  We are pioneering a new age of boundless discovery by building the capabilities to apply AI to every aspect of the scientific method.  We are introducing scientific superintelligence to solve humankind's greatest challenges, enabling scientists to bring forth solutions in human health, climate, and sustainability at a pace and scale never experienced before. Learn more about this mission at  www.lila.ai    

At Lila, we are uniquely cross-functional and collaborative. We are actively reimagining the way teams work together and communicate. Therefore, we seek individuals with an inclusive mindset and a diversity of thought. Our teams thrive in unstructured and creative environments. All voices are heard because we know that experience comes in many forms, skills are transferable, and passion goes a long way.

If this sounds like an environment you’d love to work in, even if you only have some of the experience listed below, please apply.

🌟 Your Impact at Lila

We are seeking a Senior Backend Engineer to join our software group and help build the next generation AI-driven scientific platform. In this role, you will design, build, and optimize backend systems that power intelligent, data-driven applications. You will focus on creating high-performance APIs, architecting scalable data management tooling, and ensuring the reliability of services that integrate advanced AI frameworks with complex scientific analytics and laboratory workflows.

You’ll work closely with ML researchers, platform engineers, and scientists to develop systems that can handle diverse workloads and scale seamlessly, including structured SQL database, data lake houses, and vector databases. This is an opportunity to apply your deep backend expertise to a cutting-edge AI platform with real scientific impact. If you are passionate about designing performant, elegant backend systems, we would love to hear from you!

🛠️ What You'll Be Building

  • Design & Build APIs: Design and build high-performance, secure, and well-documented APIs that integrate with AI-driven applications.
  • Database Architecture & Scaling: Architect schemas and manage diverse data systems (SQL, NoSQL, Vector DBs, and others) for optimal performance and scalability.
  • Backend Systems Development: Drive the implementation of backend services, focusing on performance, maintainability, and reliability.
  • Performance & Reliability: Diagnose and optimize system bottlenecks, ensuring high availability and low-latency performance across large-scale workloads.
  • Cloud & Infrastructure: Leverage AWS services, Kubernetes and modern DevOps practices to build and deploy production-grade systems at scale.
  • Cross-Functional Collaboration: Work with ML researchers, engineers, and scientists to integrate data pipelines, APIs, and cloud infrastructure into scientific workflows.

🧰 What You’ll Need to Succeed

  • Bachelor’s or Master’s degree in Computer Science, Engineering, or related field.
  • 4-8 years of backend engineering experience building and deploying large-scale systems in production.
  • Expertise in Databases: Strong experience with SQL, NoSQL, and emerging database technologies (e.g., Vector DBs); proven track record in schema design, indexing, and query optimization.
  • API Development: Proven ability to design and scale RESTful or GraphQL APIs with a focus on reliability and performance.
  • Python Expertise: Strong experience with Python for backend services (e.g., FastAPI, Flask, Django).
  • Cloud & DevOps Knowledge: Hands-on experience with AWS, GCP, or Azure; strong understanding of Kubernetes and containerization, infrastructure-as-code (Terraform, CloudFormation), and CI/CD pipelines (GitHub Actions).
  • Communication & Collaboration: Acute listening skills, and a proven track record of working cross-functionally with scientists, data engineers, and product teams; able to explain complex ideas to diverse audiences.
  • Problem Solving: Proven ability to take ownership of complex backend challenges, balancing trade-offs between scalability, performance, and maintainability.

✨ Bonus Points For

  • Hands-On with Latest AI Tools: Exposure to AI technologies such as Large Language Models (LLMs), Retrieval-Augmented Generation (RAG), or agentic frameworks, as well as experience leveraging AI to improve development performance.
  • Scientific or Data-Intensive Domains: Experience working with life sciences, material sciences, or other research-heavy fields.
  • Leadership & Mentorship: Experience guiding peers in backend best practices, performance optimization, and system design.
  • Orchestration Systems: Experience with orchestration tools (Flyte, Kubeflow, Airflow, Prefect, Dagster).
  • Domain Background: Exposure to analytics for life sciences, material sciences, or related fields.

🌈 We’re All In

Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

🤝 A Note to Agencies

Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.

Top Skills

AWS
Azure
CloudFormation
Django
Fastapi
Flask
GCP
Github Actions
Kubernetes
NoSQL
Python
SQL
Terraform
Vector Dbs
HQ

Flagship Pioneering Cambridge, Massachusetts, USA Office

55 Cambridge Parkway, Suite 800E, Cambridge, MA, United States, 02142

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