Pfizer Logo

Pfizer

Senior Associate Scientist

Posted 4 Hours Ago
Be an Early Applicant
Hybrid
Andover, MA
67K-111K
Mid level
Hybrid
Andover, MA
67K-111K
Mid level
Develop and optimize downstream purification processes for biotherapeutics and vaccines, ensuring effective execution and documentation in a laboratory setting.
The summary above was generated by AI
Why Patients Need You
Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.
What You Will Achieve
Deliver results in a fast-paced matrix-oriented setting, be a contributor to key process purification steps and hold responsibility for various downstream process development activities. This advertised role is in support of products and process development for biotherapeutics and vaccines, including antibodies, antibody-drug conjugates, therapeutic proteins, and polysaccharides in commercial operations and late-stage clinical development. The candidate will work across downstream purification functions, projects, and global sites.
In this role, you will:
  • The MSAT downstream purification group is responsible for providing support to the upstream team, as well as downstream development purification/optimization, mRNA drug substance/drug product process activities, and providing support to routine manufacturing operations
  • Candidate should have scientific knowledge and experience in techniques such as mRNA Drug Substance process, LNP formulation, UF /DF, Column Chromatograph, and ideally familiar with standard downstream equipment, e.g. AKTAs
  • Familiar with concepts of process development and qualification of purification techniques.
  • Ensure the proper and timely execution in all aspects of downstream processing to support group activities
  • Perform scale-down purifications of biologics including enzymes using precipitation, depth filtration, ultrafiltration and chromatography under supervision of lab supervisor/designee
  • Ensures effective, high-quality, timely and appropriate documentation in electronic laboratory notebooks and internal technical reports; presents data/ strategy to scientists and management in appropriate internal and external venues (technical meetings, project team meetings, conferences) as appropriate.
  • Contributes to safe, efficient, effective and harmonious lab environment, ensures appropriate cleanliness and status/ operability of shared or assigned lab space or equipment; strong lab citizen and collaborative team player; approaches the job with energy and commitment; frequently demonstrates initiative.
  • Participate in multi-disciplinary teams to resolve complex issues - Assist in manufacturing investigations and process troubleshooting - Assist on process improvement projects
  • Participate in organizational initiatives aligning to Six Sigma practices

Here Is What You Need (Minimum Requirements)
  • Applicant must have a Bachelor's degree with at least 2 years of experience; OR a Master's degree with 0+ years of experience; OR an Associate's degree with 6 years of experience; OR a high school diploma (or equivalent) and 8 years of relevant experience
  • Experience with interdisciplinary drug development teams and industrial experience developing purification strategies and methods in support of product and process development and to assess the quality and characteristics of biotherapeutics.
  • Demonstrated technical writing skills
  • Experience with technologies focused on mRNA drug substance process such as In-vitro transcription reactions, LNP formulations, AKTA, UF/DF, Column Chromatography, mRNA drug substance/drug product operations

Bonus Points If You Have (Preferred Requirements)
  • Demonstrated technical skills and scientific expertise in purification process development and troubleshooting
  • Experience with Microsoft Office, Excel, Word, etc.
  • Curiosity about seeking and applying current relevant scientific literature.

Physical/Mental Requirements
  • Possess effective oral and written communication skills.
  • Enthusiastic about communicating to a broad range of stakeholders (from novices to experts) and seeking agreement in complex situations.
  • Change agile, functional in a fast-paced team environment where multi-tasking required.

Non-Standard Work Schedule, Travel, or Environment Requirements
  • This role is standard day Monday through Friday work shift. May require some out of hours working to support business needs.

Other Job Details:
  • Last day to Apply: July 10th, 2025
  • Eligible for Relocation Assistance: No
  • Work Location Assignment: on site

The annual base salary for this position ranges from $66 500,00 to $110 900,00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7,5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Research and Development

Top Skills

Akta
Column Chromatography
Excel
Lnp Formulation
MS Office
Mrna Drug Substance Process
Uf/Df
Word

Similar Jobs at Pfizer

10 Days Ago
Hybrid
Andover, MA, USA
67K-111K Annually
Mid level
67K-111K Annually
Mid level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
The Senior Associate Scientist will develop LCMS assays for protein quantification, manage experimentation, and collaborate with teams, enhancing bioanalytical processes.
Top Skills: LcmsMS OfficeSkylineXcalibur
4 Hours Ago
Hybrid
Andover, MA, USA
80K-134K
Junior
80K-134K
Junior
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
The Scientist role focuses on downstream process development for biotherapeutics and vaccines, involving purification activities and optimization techniques.
Top Skills: AktaColumn ChromatographyEnzymatic ReactionsMS OfficeMrna Drug Substance ProcessUf/Df
Yesterday
Hybrid
Andover, MA, USA
29-49
Junior
29-49
Junior
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
Oversee maintenance tasks, manage individual contributions, follow procedures, identify routine problems, and perform preventative maintenance on various equipment.
Top Skills: Cmms

What you need to know about the Boston Tech Scene

Boston is a powerhouse for technology innovation thanks to world-class research universities like MIT and Harvard and a robust pipeline of venture capital investment. Host to the first telephone call and one of the first general-purpose computers ever put into use, Boston is now a hub for biotechnology, robotics and artificial intelligence — though it’s also home to several B2B software giants. So it’s no surprise that the city consistently ranks among the greatest startup ecosystems in the world.

Key Facts About Boston Tech

  • Number of Tech Workers: 269,000; 9.4% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Thermo Fisher Scientific, Toast, Klaviyo, HubSpot, DraftKings
  • Key Industries: Artificial intelligence, biotechnology, robotics, software, aerospace
  • Funding Landscape: $15.7 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Summit Partners, Volition Capital, Bain Capital Ventures, MassVentures, Highland Capital Partners
  • Research Centers and Universities: MIT, Harvard University, Boston College, Tufts University, Boston University, Northeastern University, Smithsonian Astrophysical Observatory, National Bureau of Economic Research, Broad Institute, Lowell Center for Space Science & Technology, National Emerging Infectious Diseases Laboratories

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account