Senior Associate Scientist, In Vitro Pharmacology

Use Your Power for Purpose
At Pfizer, our purpose is to deliver breakthroughs that change patients' lives. As a Senior Associate Scientist Biology, you will be at the forefront of our mission, contributing to the development of innovative therapies and vaccines that have the potential to transform patient care. Reporting to the Research & Development division, you will leverage advanced science and cutting-edge technologies to make a tangible impact on global health. Your work will be instrumental in ensuring drug safety and efficacy, supporting clinical trials, and accelerating the delivery of top-tier medicines to patients worldwide.
What You Will Achieve
In this role, you will:

• Be responsible for the design, development and execution of in vitro experiments to generate decision making data for portfolio programs.
• Become an integral member of research project biology teams where you will be responsible for recommending options for in vitro experimentation, generation of high-quality in vitro pharmacology data and report results and conclusions at project team meetings.
• Design develop and execute in vitro experiments to assess the potency and efficacy of molecules.
• Utilize single and multicolor flow cytometry to assess affinity and potency of molecules.
• Perform single and multiplexed MSD/conventional ELISA experiments to quantify cellular cytokine release.
• Work with whole blood and perform isolation and differentiation of cell subsets.
• Independently perform data analysis and present results at project meetings.

Here Is What You Need (Minimum Requirements)

• Bachelor's degree in Immunology or Pharmacology with
  3+ years experience performing in vitro based experiments in a Pharma/Biotech lab environment.
• Previous experience in generating and analyzing single and multicolor flow cytometry data.
• Experience with MSD & ELISA experimentation.
• Experience in plate-based experimentation and serial dilutions of large and small molecules.
• Strong understanding of fundamental in vitro pharmacology parameters and how to design and execute plate-based experiments to quantify them.
• Confidence in troubleshooting experimental/assay challenges.
• Good sterile techniques for culture and maintenance to primary and immortalized cell lines.
• Competent user of Excel, GraphPad Prism and PowerPoint for data analysis and presentation of results.

Bonus Points If You Have (Preferred Requirements)

• Prior experience in working with both large and small molecule therapeutic modalities.
• Experience in drug discovery processes.
• Excellent organizational and time management skills.

PHYSICAL/MENTAL REQUIREMENTS
Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Adhere to safe laboratory work practices and procedures.
Additional Information:

• Work Location Assignment: On Premise
• Last Day to Apply: March 5, 2026

The annual base salary for this position ranges from $68,600.00 to $110,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Research and Development