Scientist, Serology

Scientist, Serology

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At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.

We believe the Greater Boston area is an important hub for the biotech and pharma industry, which is why we’ve invested in growing our footprint and expanding our R&D space in Cambridge, with a primary focus on additional state-of-the-art lab space. Here, we will bring together talent and expertise, building upon GSK’s long history of vaccine development, to create globally leading viral capabilities and cutting-edge vaccines technologies, as we add to our robust portfolio targeting infectious diseases at every stage of life.

In the plan to create a new hub for mRNA-based vaccine discovery in Cambridge, we are building new laboratories that will be focused on the development of state-of-the-art methods that will be supporting deep product understanding, process and product development, as well as testing of pre-clinical and clinical samples for new mRNA-based vaccines.

This is a Scientist position in the Serology and Assay Development team in Viral Vaccines.  You will help develop and execute serological assays to be used for the evaluation of vaccine candidates and therapeutics.  You will bring significant knowledge of immunology and virology, and experience in executing biological assays, which provide critical information to enable strategic decision making by the project teams.

We are looking for a highly motivated, innovative scientist with experience in multiple ligand binding formats, neutralizations, and Fc effector function assays who is willing to go the extra mile to contribute to multiple projects and help develop vaccine candidates and therapeutics through preclinical development.

Key Responsibilities:

• Help develop, validate and execute serology-related assays to assess antibody responses
• Plan and execute viral neutralization assays
• Growing up and quantifying viral stocks
• Plan and execute ligand binding assays in multiple formats
• Develop and execute cell-based assays including viral neutralization assays, Fc receptor activation assays, ADCC, and ADCP
• Analyse and interpret experimental data and document results in electronic notebooks in a detailed and consice manner
• Write detailed protocols, procedures and work instructions to support immunology assays.
• Write specific technical sections of internal and external reports and contribute to scientific papers and patents
• Reporting of results in team meetings and cross-function and cross-depeartment meetings
• Highly organized, able to keep track of key project-related deadlines
• Help with lab managemenet tasks including the ordering of materials, participation in operational meetings, routine equipment maintenance
• Contribute to the maintenance of a clean and safe workplace

Basic Qualifications:

• Degree in Immunology, Virology, Microbiology, Pharmaceutical Sciences, or related scientific field.
• PhD with 0+ years of postdoctoral or industry experience, MS with 4+ years of lab experience, or BS with 6+ years of lab experience. 
• 1+ years of experience with ELISA, Luminex, or MSD and/or cell-based assays including viral neutralization assays, Fc receptor activation assays, ADCC, and ADCP

Preferred Qualifications:

• At least three years of experience developing ligand binding assays or viral neutralization assays
• Prior experience with the implementation of robotic systems to increase analytical efficiencies.
• Prior experience with the analysis of human biological samples (HBS) and knowledge of the HBS specific precautions.
• Multiple years of experience in developing analytical templates in SoftMax Pro, Prism and other analytical software.
• Prior experience in statistical analysis.
• Experience in qualification and/or validation of assays for regulatory filings.
• Strong track-record of scientific publications in peer-reviewed journals or other demonstrations of scientific success.

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Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

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GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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