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Sail Biomedicines

Scientist I/II - Integrative Biology

Reposted 17 Hours Ago
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In-Office
Cambridge, MA
Junior
In-Office
Cambridge, MA
Junior
The Scientist I/II will develop and scale assays for RNA medicines, collaborate with teams, optimize testing protocols, and assist in laboratory experiments.
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Title: Scientist I/II Integrative Biology

Manager: Principal Scientist, Integrative Biology 

Type: Onsite  

About Sail:

Sail Biomedicines is harnessing evolutionary and artificial intelligence to revolutionize programmable medicines. Sail’s platform combines first-in-class programmable RNA technology (Endless RNATM or eRNA), and an industry-leading platform of programmable nanoparticles, utilizing natural components, to unlock comprehensive programming of medicines for the first time. By leveraging cutting-edge eRNA and nanoparticle deployment technology, Sail is building a wealth of data, enabling unparalleled use of AI techniques to identify and design fully programmable medicines that are potent, targeted, versatile, and tunable. Sail was founded by Flagship Pioneering.

The Role:

Sail Biomedicines is seeking a highly motivated Scientist I/II to join the Integrative Biology group at Sail Biomedicines. Collaborating with an interdisciplinary team experienced in molecular biology, bioengineering, pharmacology, data science, and machine learning, this individual will develop and scale robust assays to discover the next generation of RNA medicines. The ideal candidate will bring a track record of scientific initiative and a deep commitment to teamwork to the Integrative Biology group’s fast-paced culture of scientific rigor. 

This lab-based onsite position requires the majority of time to be dedicated to hands-on lab work, focusing on experimental tasks and collaboration within the team to drive project success.

Responsibilities:

  • Help us build Sail’s core technological platform and discover novel therapeutics.  
  • Operate outside your scientific comfort zone to lead and support multiple projects from ideation through execution. 
  • Optimization and standardization of serology and molecular assays  
  • Generate endpoint data for in vivo studies including, but not limited to flow cytometry and molecular assay readouts 
  • Assist other team members in performing laboratory experiments as needed 
  • Maintain accurate and up to date laboratory notebooks 

Qualifications: 

  • PhD in immunology, microbiology or a closely related field.
  • Strong background in experimental design, data analysis, and interpretation. 
  • Effective communication with both technical and non-technical audiences. 
  • Proficiency in developing and performing serology and cell-based assays. 
  • Ability to work effectively with minimal direction and oversight.  

Desired Qualifications: 

  • Experience in conducting preclinical vaccine studies and processing animal tissue samples 
  • Experience in cell and tissue culture experiments, serology assays (ELISAs, bead-based Luminex assays), T cell assays (flow cytometry based immunophenotyping, intracellular cytokine assays and ELISPOT). Experience with automation would be an asset.  
  • Solid grounding in data analysis and statistics 

  

Sail Biomedicines is an Equal Opportunity Employer. Sail does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, national origin, veteran status, or any other status protected under federal, state, or local law.

Top Skills

Data Analysis
Elisas
Flow Cytometry
Luminex Assays
Molecular Assays
Nanoparticles
Rna Technology
HQ

Sail Biomedicines Somerville, Massachusetts, USA Office

101 South St, Somerville, Massachusetts , United States, 02143

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