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Prudentia Sciences

Scientific Director

Reposted Yesterday
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In-Office or Remote
Hiring Remotely in Boston, MA, USA
Senior level
In-Office or Remote
Hiring Remotely in Boston, MA, USA
Senior level
Drive scientific strategy for the AI platform, shape scientific models, serve as a scientific advisor to clients, ensuring scientific integrity and developing methodologies for drug development.
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About Prudentia Sciences

Prudentia Sciences is an AI-powered technology platform transforming how biopharma, biotech, and life sciences investors approach portfolio management, due diligence, and value and risk simulation. Our platform accelerates investment in breakthrough therapies by:

  • Empowering biopharma to accelerate drug pipelines, maximize ROI, and achieve clinical and commercial success for greater patient impact
  • Enabling strategic positioning of asset value during portfolio planning and dealmaking
  • Equipping investors with data-driven insights to optimize capital allocation in drug asset transactions

Backed by GV (Google Ventures), Iaso Ventures, Virtue, McKesson, and SignalFire, we're on a mission to unlock the full potential of pharmaceutical R&D by empowering decision-makers with real-time, data-driven insights.


The Opportunity

We are seeking an exceptional Scientific Lead to drive the scientific strategy of Prudentia Sciences. This is an opportunity to shape how an AI platform thinks—influencing the scientific models, frameworks, and assumptions that power our product—while also engaging directly with our biopharma customers as a credible, trusted scientific advisor.

You will sit at the intersection of science, product, and commercial strategy. You will partner with our commercial teams on enterprise deals, serve as a scientific sounding board for clients navigating complex investment decision-making, and drive the scientific rigor of our platform. This role is for someone who has lived the end-to-end drug development process and wants to apply that expertise to build something transformative.

What You'll Do

Shape the Scientific Strategy of Our Platform

  • Own the scientific integrity of the Prudentia platform—defining how scientific domains, risk frameworks, and value drivers are modeled and represented across therapeutic areas and development stages
  • Partner closely with Product and Engineering to translate scientific knowledge into platform features that reflect life sciences decision-making
  • Develop and maintain scientific content and methodologies across key domains including preclinical and clinical development strategy, safety and toxicology, CMC, commercial, regulatory, and IP
  • Ensure the platform stays current with evolving industry standards and emerging evidence, proactively identifying gaps and opportunities to enhance scientific credibility and value
  • Build a scientific knowledge base that can scale: benchmarks, reference datasets, and content that powers the platform’s recommendations and analyses

Serve as Scientific Advisor to Commercial Teams

  • Serve as the resident scientific expert supporting Sales and Customer Success in client engagements, providing scientific credibility in conversations with executive-level pharma decision-makers across R&D, BD&L, and Portfolio Strategy
  • Help customers and prospects understand how to use Prudentia to evaluate deal candidates and make investment decisions with greater confidence
  • Lead scientific discovery sessions with prospective and existing clients to understand their pipeline challenges, identify use cases, and map Prudentia’s capabilities to their strategic objectives
  • Support development of scientific narratives, case studies, and proof-of-value materials that demonstrate the impact of the platform

Provide Scientific Support to Customers

  • Act as a scientific resource for select strategic accounts, reviewing platform outputs with clients, contextualizing results within their therapeutic and competitive landscape, and helping them extract maximum scientific value from the Prudentia platform
  • Support facilitation of scientific workshops, executive briefings, and onboarding sessions that build client confidence and deepen platform engagement
  • Collaborate with the Customer Success team to proactively identify at-risk accounts or underutilized workflows where deeper scientific engagement could drive retention and expansion

Drive Scientific Thought Leadership

  • Represent Prudentia Sciences at industry conferences, advisory boards, and scientific forums, building visibility and credibility in the biopharma and life sciences investment communities
  • Develop white papers, educational content, and scientific commentary that position Prudentia as a trusted voice in AI-driven drug development decision-making
  • Stay deeply connected to the pharma BD&L and portfolio management ecosystem
  • Provide scientific input to fundraising narratives, investor materials, and strategic partnerships as needed


Who You Are

Essential Qualifications

  • Advanced degree (PhD, MD, or PharmD) in a relevant life science discipline
  • 8+ years of experience spanning multiple stages of drug development—from discovery through commercialization—ideally with direct exposure to R&D and/or business development and licensing
  • Proven ability to engage executive-level pharma stakeholders as a scientific peer
  • Experience working at or closely with large pharma or biotech organizations in Search & Evaluation, Business Development, Portfolio Strategy, R&D Strategy, or Medical Affairs
  • Strong scientific communication skills: able to synthesize complex information into clear, compelling narratives for both scientific and business audiences
  • Comfort operating in a fast-paced, high-growth startup environment where priorities evolve and the ability to move quickly while maintaining scientific rigor is essential


Bonus points

  • Direct experience in pharma BD&L—deal evaluation, term sheet negotiation, licensing agreements, or asset acquisition
  • Experience with AI/ML platforms, decision intelligence tools, or advanced analytics in a pharma or life sciences context
  • Therapeutic breadth across multiple indications (oncology, rare disease, CNS, immunology, etc.) and development stages (early, late, launch)
  • Experience as a scientific advisor, consultant, or KOL to pharma companies or investment firms
HQ

Prudentia Sciences Cambridge, Massachusetts, USA Office

245 Main St, Cambridge, MA, United States, 02142

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