At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients.
Job Summary:
We are seeking a highly motivated Biology/Biochemistry Research Associate II to join our In Vitro Pharmacology team. You will be able to work alongside our team to design and execute in vitro experiments that support preclinical drug discovery, including disease modeling and proof of mechanism validation to characterize our platform candidates. The ideal candidate is a skilled lab-based in vitro biologist driven to contribute to a rigorous scientific environment and a consummate team player. This is a great opportunity to become an integral member of a diverse drug discovery team with ample prospects to progress their career development in drug discovery.
Primary Responsibilities:
- Execute a wide array of experiments in cellular and molecular biology.
- Perform cell culture routinely; establish and characterize innovative cell lines for disease modeling and pharmacology studies.
- Actively contribute to the design and troubleshooting of experimental studies, nurturing collaboration with biology teams and cross-functional project groups.
- Provide essential support for the daily operations of biology labs.
- Review the literature to bring in the newest scientific findings, ideas, methods, and technologies for discovery research.
- Maintain accurate and detailed laboratory records.
- Collaborate with team members on multiple research projects.
Qualifications:
- M.S. or B.S. in cell biology or related disciplines.
- A minimum of 2-3 years of hands-on experience in cellular and molecular biology techniques, including but not limited to flow cytometry, RT-qPCR, western blotting, siRNA/shRNA silencing, CRISPR/CAS9 knockout, plasmid construction and preparation, lentiviral/retroviral transduction, and ELISA-based assays.
- Proficiency in cell culture techniques, including both immortalized cell lines & primary cells.
- Previous exposure to organoids or multicellular culture models and experience in Flow Cytometry is highly regarded.
- Excellent written and verbal communication skills, as well as strong organizational and problem-solving abilities.
- Enthusiasm for scientific research and a desire to learn and contribute.
This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, and other relevant factors.
Our Diversity, Equity & Inclusion Mission Statement: Keros is an inclusive company. We believe that diversity drives innovation. We continue to build an inclusive culture that encourages, supports, and celebrates the diverse voices of our employees. As such, Keros takes a holistic approach in mentoring, coaching, and developing all of our Keros team members.
Keros Therapeutics is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.
Recruitment & Staffing Agencies:
Keros Therapeutics does not accept unsolicited resumes from any source other than the candidate directly. Any unsolicited submission by an agency to Keros is prohibited. Any resume submitted by an agency without a signed contract or expressed consent by a member of the Keros Therapeutics Human Resources Department, will be considered property of Keros Therapeutics, and no fee shall be owed with respect thereto.
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Keros Therapeutics Lexington, Massachusetts, USA Office
1050 Waltham St, Suite 302, Lexington, Massachusetts , United States, 02421
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