Principal Technical Program Manager

The Role:

Moderna is seeking an experienced and visionary candidate to join Digital Commercial Engineering (DCE) team based in Cambridge, MA. This role will be pivotal in supporting Moderna’s Commercial endeavor across multiple geographies, helping to drive digital innovation and execution that enables Moderna to deliver on its mission of creating transformative medicines for patients around the world.
As a senior member of the DCE organization, you will partner with business stakeholders across Moderna’s Commercial team to deeply understand their digital and operational needs, translate business requirements into actionable technical roadmaps, and work closely with multiple engineering and product teams to deliver scalable, compliant, and high-impact digital solutions.
You will operate at the intersection of business and technology—aligning commercial strategy with digital delivery—while influencing strategic prioritization, operational planning, and stakeholder engagement across geographies.

Here’s What You’ll Do

• Partner with Business Stakeholders across Moderna’s Commercial Country teams to deeply understand digital, customer, and business needs. Define and document clear business and technical requirements, translating them into actionable deliverables that shape product direction, resourcing, and execution plans in collaboration with Digital Product and Engineering teams.

• Lead end-to-end program planning and execution, developing integrated delivery roadmaps, managing scope, schedules, dependencies, and budgets, while proactively identifying and mitigating risks and challenges to ensure alignment, momentum, and on-time delivery of commercial initiatives.

• Facilitate cross-functional collaboration among Product, Engineering, and Business teams to drive consensus on technical solutions, resolve dependencies, and ensure timely, high-quality delivery.

• Drive data-informed prioritization and transparent reporting to provide visibility into program progress, key decisions, risks, and outcomes, while representing the Digital portfolio in leadership forums to influence strategic direction, communicate business impact, and ensure alignment across commercial functions.

• Champion operational excellence in digital delivery, promoting modern program management practices, process optimization, and continuous improvement across teams.

• Mentor and coach TPMs and project managers, strengthening delivery capabilities and contributing to the maturity of the TPM discipline within Moderna Digital.

Here’s What You’ll Need (Basic Qualifications)

• Bachelor’s degree in Computer Science, Engineering, or a related technical field (or equivalent professional experience).

• 10+ years of overall professional experience, with at least 6+ years in technical program management for complex, cross-functional software or digital initiatives.

• Proven ability to manage large-scale technical programs with multiple stakeholders, spanning business and technology functions. Experience managing programs with multi-market scope.

• Strong analytical and communication skills, with the ability to influence at multiple organizational levels. Demonstrated success in partnering with business leaders to translate strategy into executable roadmaps.

• Degree in advanced technology, or 5+ years of technical specialist, design and architecture experience. Proven skills in technical design and architecture.

• Experience in commercial digital systems, customer platforms, or enterprise-scale business systems supporting multi geography markets.

• Familiarity with regulated industries (biotech, pharma, healthcare) and understanding of compliance, data privacy, and localization requirements.

• Demonstrated ability to build, influence, and manage strong relationships with both Business and Technical stakeholders across multi geography teams.

• A mindset aligned with Moderna’s values: Bold, Relentless, Curious, and Collaborative.

• Evidence of Moderna Mindsets: We behave like owners – driving results that go beyond any job description; We act with dynamic range – balancing strategy and execution seamlessly; We prioritize the platform – enabling scalability and sustainability over point solutions.

Here’s What You’ll Bring to the Table (Preferred Qualifications)

• Proven track record of balancing strategic priorities with hands-on execution, delivering measurable business outcomes through disciplined program leadership.

• Exceptional communication, facilitation, and stakeholder management skills, with the ability to translate complex technical topics into clear business insights.

Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work.  That’s why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between.

• Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs

• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support

• Family planning benefits, including fertility, adoption, and surrogacy support

• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown

• Savings and investment opportunities to help you plan for the future

• Location-specific perks and extras

The salary range for this role is $158,600.00 - $285,500.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.  

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. 

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. 

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. 

Our Working Model 

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. 

Moderna is a smoke-free, alcohol-free, and drug-free work environment. 

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.  Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. 

Accommodations

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. 

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [email protected]. 

Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license. #LI-CK1

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