Principal Research Associate, Bioanalytical

Job Description

Employer:                         Vertex Pharmaceuticals Incorporated 

JOB TITLE:                         Principal Research Associate, Bioanalytical          

LOCATION:                       316-318 Northern Ave, Boston, Massachusetts, 02210

OPENINGS:                        1

DUTIES:

• Conduct bioanalytical assays to support preclinical study sample analysis.
• Carry out method development and optimization to quantify target proteins.
• Maintain proper documentation of experiments and support QC data review.
• Collaborate with cross-functional teams to review study design and interpret results.
• Prepare technical reports and presentations to document and communicate results.

REQUIREMENTS:              Employer will accept a Master’s degree or equivalent, in applied science, biotechnology or a related field and 3 years of experience in the job offered or in a Principal Research Associate, Bioanalytical-related occupation.

Position requires demonstrable experience in the following:

Perform biochemical and ligand binding assays to support sample analysis from preclinical studies including protein extraction and quantification, automated capillary western blot, ELISA, MSD and ELISPOT. Drive splenocyte isolation and cell culture. Coordinate sample storage, data analysis and interpretation using GraphPad PRISM. Perform assay development, optimization, and qualification according to FDA guidelines for bioanalytical method validation. Execute and document assays ELN with good laboratory practices and good documentation practices. Coordinate biodistribution, toxicology and pharmacology studies for investigational new drug application. Conduct biochemistry and molecular biology on CRISPR strategies for gene and cell therapies.  Perform statistical analysis including 4PL, regression analysis, standard deviation and coefficients of variation calculations.

Rate of Pay:                      $86500.00 - $129800.00

CONTACT:                         Send Resume to [email protected]. Reference 12140.705. EOE.

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.  

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]