Principal Program Manager

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!  

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics. 

Why Join Us? 

• Innovative Environment: Help to pioneer advancements in cancer immunotherapy. 

• Collaborative Culture: Be part of a diverse team dedicated to your professional growth. 

• Global Impact: Contribute to therapies that make a lasting impact on patients globally. 

We are seeking a Principal Program Manager (Patient Journey Navigator), that is primarily responsible for managing each patient journey from ICF1 through randomization and treatment until the first scan for primary end point in our Phase 3 trial. This dynamic role requires an outstanding ability to manage patient cases by coordinating between medical professionals at sites and Immatics cross-functional teams to progress patients quickly and efficiently through the vein-to-vein (V2V) journey.  

FLSA Classification: Salary, Exempt  
Schedule: 8:00 AM – 5:00 PM; Monday to Friday; On-site or Remote 
Reports to: Senior Director 
Location: 13203 Murphy Road Suite 100 Stafford, TX 77477 or Fully Remote 

Salary Range: $160,000 to $175,000 

What You’ll Do: 

As a Principal Program Manager, you will play a key role in supporting our clinical operations program management team: 

• Learn the clinical trial protocol (all versions) and pass the Patient Journey Navigator QC check. 

• Spearhead the touchpoint calls with the site staff as and when scheduled, take meeting minutes and organize the patient journey in real time. Follow up with the site on the next steps to expedite randomizations. 

• Align internally with stakeholders (Clinical Operations, Patient Journey Leader, Clinical Development, Clinical Sciences, Global Patient Supply, Project Management, GMP Operations, Quality Control, Quality Assurance) before providing the sites with guidance.  

• Follow the blueprint patient journey to enable randomizations as quickly as possible for patients that are eligible and pass VA eligibility. 

• Design the patient journey in real time during the touchpoint call for each patient depending on their unique needs and site constraints. 

• Independently manage patient V2V workflows to achieve our operational excellence goals of rapid movement pre and post randomizations above the industry benchmark. 

• Align with the patient journey lead on MVR slots, randomization dates and manufacturing start dates. 

• Provide guidance to the site on EDC sections that must be completed prior to randomization.  

• Collaborate with internal and external teams for Out of Specifications communication. 

• Be a trusted and knowledgeable contact that is “nearly always available” for the site's stakeholders to enhance the Immatics experience. Ability to answer questions after hours. 

Required Experience and Education: 

• At least master's degree in life sciences, medicine, pharmacy, health or a comparable education.   

• Proven experience (2+ years) in clinical program management, healthcare administration, GPS, CMC Cell therapy, Med. Affairs or related field (including experience in late-stage clinical programs   

• Knowledge in immunology, oncology  

• Expertise in strategic planning, risk management, and change management   

• Strong operational leadership skills, communication, presentation and business partnering ability   

• Demonstrated ability to build strong customer relationships   

• Ability to analyze complex business issues and opportunities 

Preferred Experience and Education:  

• Clinical Operations, GPS, Project Management, CMC Cell therapy or Medical Affairs background would be preferred 

• Proficiency in project management according to industry standard and hands-on experience in using project management tools and software.   

• Knowledge in cell and gene therapy  

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Competencies  

• Initiative 

• Problem Solving 

• Critical Thinking 

• Interpersonal Communication 

• Customer Service 

• Attention to Detail 

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Work Environment:  

This is a sedentary position (at least 50% of time) in a typical office environment. There may be frequent interruptions with moderate noise levels and frequent use of printers, copiers, scanners, computers and other office equipment. Ability to sit, talk, walk, hear and communicate verbally and in writing is required. Occasional lifting of objects up to 25 lbs is expected.    

• Travel Requirements: 

• Remote: Regular travel to Houston or designated sites for PI engagement may be required (approximately 10 trips per year). 

• Houston-based: Limited travel to sites for PI engagement may be required (approximately 3 trips per year). 

Physical demands: 

• Communicating Verbally – expressing or exchanging ideas by means of the spoken word to impart oral information to others to convey detailed spoken instructions or other workers accurately, loudly or quickly. 

• Hearing – the ability to hear, understand, and distinguish speech and/or other sounds one-on-one, group or conference, telephone, and other sounds. 

• Keyboarding – entering data or text into a computer or other machine by means of a keyboard. Devices include a traditional keyboard, 10 key-pad, touch screens and others.  

• Lifting - raising or lowering an object (up to 25 lbs) from one level to another (includes upward pulling). Carrying is to transport an object – usually by holding it in the hands or arms but may occur on the shoulder. 

• Near Visual Acuity – clarity of vision at approximately 20 inches or less (working with small objects, reading small print, including the use of computers).  

• Pushing - Exerting force upon an object so that the object moves away from the object. 

• Pulling - Exerting force upon an object so that the object moves toward the force.  

• Sitting – remaining in a sitting position for at least 50% of the time. 

• Standing/Walking - remain on one's feet in an upright position at a workstation.  

• Stooping – occasional bending the body downward and forward by bending the spine at the waist - requiring full use of the lower extremities and back muscles. 

Work authorization/security clearance requirements:  

Legal eligibility to work in the United States is required. Immatics participates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment   

Affirmative Action/EEO statement:   

Immatics is an equal opportunity employer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs.  

What do we offer?  

At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics 

Comprehensive Benefits:  

• Competitive rates for Health, Dental, and Vision Insurance 

• 4 weeks of Paid Time off, granted up front each year and prorated for first and last year of employment. 

• Sick Time Off – 56 hours  

• 12 Paid Holidays  

• 100% Employer-Paid Life Insurance up to at 1x annual salary, up to 100K ( club together) 

• 100% Employer Paid Short- and Long-Term Disability Coverage  

• 401(k) with Immediate Eligibility  & company match… 

• You are eligible for 401(k) plan participation as of your first paycheck. 

• The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment. 

• Partially paid Parental Leave for eligible employees. (3 weeks) 

• Additional voluntary employee paid coverages including  Accident, Hospital Indemnity, and Critical Illness Employee Paid Identity Theft Protection and Pet Insurance.  

Professional Growth:  

• Opportunities to work with leading experts in the field of T-cell immunotherapy.  

• Company provided learning and development opportunities 

• Fast paced, high demand collaborative and dynamic environment.