Principal Clinical Data Science Lead

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development

We are currently seeking a Principal Clinical Data Science Lead to join our diverse and dynamic team. As the Principal Clinical Data Science Lead at ICON, you will be responsible for guiding and overseeing the application of advanced data science methodologies to clinical research and development. Your role will involve leading data science initiatives, driving innovation in data analysis, and ensuring that insights derived from clinical data contribute to the successful development of new therapies and treatments.

What You Will Be Doing:

• Leading the design and implementation of advanced data science methodologies and statistical models to support clinical research and data analysis.

• Guiding a team of data scientists and analysts in the development and execution of data-driven strategies to optimize clinical trial design and outcomes.

• Collaborating with cross-functional teams, including clinical, biostatistical, and regulatory experts, to ensure integration of data science insights into clinical development programs.

• Driving innovation in the use of data science tools and techniques, including machine learning and predictive analytics, to enhance the efficiency and effectiveness of clinical trials.

• Providing strategic direction and oversight for data management and analysis processes, ensuring compliance with regulatory requirements and industry best practices.

• Communicating complex data findings and insights to stakeholders, including senior leadership and external partners, to support decision-making and strategic planning.

Your Profile:

• Preferred 8+ years of experience in clinical research, including data review, medical monitoring support, or clinical operations.

• Strong understanding of clinical development processes, data review methodologies, and regulatory compliance.

• Experience working in a global matrix organization, preferably within an FSP or CRO model.

• Proven track record of strong project management skills and experience managing data management and clinical activities for large drug development programs

• Experience with all phases of development in one or more therapeutic areas preferred

• Proficiency in clinical data systems and technologies (e.g., Veeva, RShiny, Elluminate, Medidata, JReview)

• Solid understanding of clinical trial documents (protocols, statistical analysis plans, CRFs, study reports) and processes

• Strategic knowledge of FDA and ICH regulations and industry standards applicable to data capture and clinical science processes

• Strong communication, organizational, and cross-functional leadership skills

What ICON can offer you:

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values.   We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

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