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Regeneron

Physician Scientist, Cardiometabolic Genetics

Posted 25 Days Ago
Be an Early Applicant
In-Office
Cambridge, MA, USA
176K-287K Annually
Senior level
In-Office
Cambridge, MA, USA
176K-287K Annually
Senior level
Design and execute large-scale human genetics studies in cardiometabolic disease using exome sequencing and epidemiological methods. Interpret results, support target nomination and validation, collaborate with clinical development and cross-functional teams, and communicate findings via publications, presentations, and regulatory documents.
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Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Physician Scientist to join our Cardiometabolic Therapeutic Area Genetics (TAG) team at the Regeneron Genetics Center (RGC). In this role, you will use massive-scale human exome sequencing to discover and validate new therapeutic targets in obesity and obesity-associated metabolic disease, accelerating therapeutic development through new human genetics and epidemiological insights, while collaborating with RGC teams and Regeneron's pre-clinical and clinical development teams.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

  • Location: Tarrytown, NY or Cambridge, MA

Discover your role:

  • Generate key research questions, then design and execute studies and analyses to address them

  • Interpret study results and summarize insights across formats — documents, presentations, patent applications, and publications — for different audiences

  • Leverage RGC and Regeneron datasets, external resources, and the scientific/medical literature to address research questions, weighing quantitative and qualitative strength of evidence

  • Support target nomination and validation by applying RGC's human genetics capabilities alongside Regeneron's therapeutics platforms and development modalities

  • Partner with Clinical Development to evaluate clinical-stage programs and identify opportunities for human genetics studies that inform indication selection or safety evaluation

  • Participate in the intellectual life of the Cardiometabolic TAG, RGC, and Regeneron at large, helping build an inclusive culture where everyone can perform at their best

  • Represent the Therapeutic Area Genetics team in cross-functional initiatives across RGC and Regeneron

This role requires:

  • An MD with a strong background in and knowledge of human genetics and genetic epidemiology; an MD/PhD with training in translational human genetics, genetic epidemiology, or a related discipline is preferred

  • Proficiency with R or similar software, and familiarity with high-performance computing environments

  • Experience integrating different data resources to translate initial genetic findings, and familiarity with meta-analysis of genome-wide summary statistics

  • Preferred/nice to have: experience as an investigator in Randomized Controlled Trials

  • Preferred/nice to have: experience in the clinical management or medical research of cardiometabolic disease

#MDJOBS, #MDJOBSGG

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.


Where necessary, we disclose salary ranges for roles in all countries in which we operate.  The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.  Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.  If you have any questions, please speak with your recruiter. 


Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.


As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.


For jobs in Canada: this posting is for an existing position.


Salary Range (annually)

$176,100.00 - $287,300.00

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