Pharmacology Research Scientist-(Immunology)

Job Description

General Summary:

The Pharmacology Research Scientist works with a high degree of independence and is adept at conceptually outlining in vivo and in vitro immunological studies to design, execute and interpret assays to study the action of compounds on disease biology. Completes work in a resourceful, self-sufficient manner and is able to design alternative approaches to achieve desired outcomes. Keeps current on the scientific literature relevant to scientific methodology or field(s) of technical expertise. This level captures both the Research organization’s entry level for staff with a research doctoral degree (PhD) and the advanced experimental expert leading one or more critical laboratory functions with high impact on drug discovery projects.  

Key Duties and Responsibilities:

• Design and conduct elaborate, conceptually connected, multi-component immunological and pharmacological experiments 
• Collate and interpret complex data systematically and synthesizes results into a cohesive body of conclusions or recommendations to guide Project decisions and new research activities 
• Exercises solid judgment to prioritize studies, considering feasibility and Project impact 
• Performs advanced and/or complex experimental troubleshooting 
• Scours relevant scientific literature and routinely incorporate new insights into research activities 
• Identifies, prioritizes and introduces relevant emerging technologies in field of expertise to advance the existing technology platforms and create/maintain a competitive advantage 
• Explores the feasibility of applying new scientific principles/concepts or implements and validates novel experimental approaches and technologies to achieve project goals 
• Independently prepares study presentations and presents experimental conclusions at internal Group/Department or Project Team research meetings 
• Contributes significantly to patent and/or publication preparation 
• Performs other duties as assigned 

Knowledge and Skills:

• Demonstrated ability to design, execute and interpret complex immunological and pharmacological in vivo and in vitro experiments, to measure the action of compounds in disease relevant contexts 
• Expertise in the development and optimization of complex in vivo models of inflammation or autoimmune diseases
• Advanced skills in immunological techniques, such as flow cytometry, immunophenotyping, and in vitro/ex vivo cellular assays, to characterize immune responses and compound efficacy. 
• Proficiency in a wide range of in vivo techniques, including routes of administration, blood/tissue harvesting, and processing for cellular/molecular analyses of immune responses and target engagement in immune models 
• A broad working knowledge of fundamental immunology and pharmacology principles 
• Demonstrates astute understanding of own discipline and the relevant literature  
• Maintains a high level of knowledge related to current developments in the scientific Project field 
• Displays proven productivity and experimental creativity, and effective dissemination of ideas 
• Demonstrates effective, self-sufficient communication skills, especially in peer-directed presentations 
• Demonstrates awareness of other Project-related disciplines and an understanding of general concepts and some experimental detail within those areas 

Education and Experience:

• Ph.D. Immunology, pharmacology or related discipline and 0-3 years of relevant post-doctoral employment experience or, 
• Master’s degree and 3+ years of relevant employment experience or, 
• Bachelor’s degree and 6+ years of relevant employment experience 

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Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.  

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

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Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]