The Lead will drive Orca Bio's treatment center onboarding, ensure operational readiness for ORCA-T administration, and develop scalable processes. This role involves collaboration across various functions and team leadership.
More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a late-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.
Summary
The Site Onboarding & Market Enablement Lead will be responsible for driving the execution of Orca Bio’s treatment center onboarding, activation, and ongoing site engagement to ensure operational readiness for ORCA-T administration. This role will develop and implement scalable models and processes for site onboarding, treatment center certification, and institutional support to enable a smooth launch and sustained adoption of the therapy. This position will work cross-functionally with teams across commercial, operational, and clinical functions and will manage a growing team as the program scales.
Note: Travel ~ 30%
Responsibilities
- Treatment Center Onboarding, Activation & Operational Readiness
- Oversee the implementation of Orca Bio’s treatment center onboarding strategy, including certification processes, readiness milestones, SOPs, and training materials.
- Oversee onboarding activities in partnership with the field teams to ensure treatment centers meet operational, regulatory, and quality standards for ORCA-T administration.
- Design and lead a centralized onboarding and activation command center to provide day-to-day oversight, coordinate cross-functional efforts, and drive accountability.
- Collaborate across commercial, clinical, medical, regulatory, quality, supply chain, and operational requirements.
- Lead readiness reviews and site activation meetings to ensure alignment and accountability across functions.
- Identify and address onboarding challenges, bottlenecks, or resource gaps to mitigate launch risk.
- Establish KPIs, dashboards, and reporting tools to track onboarding progress and institutional readiness.
- Institutional Engagement & Enablement Strategy
- Build and maintain strong relationships with treatment center leadership, operational staff, and key opinion leaders (KOLs) to support smooth onboarding and early adoption.
- Lead institutional engagement initiatives to ensure treatment centers are equipped with the tools, resources, and knowledge needed for successful product administration.
- Partner with the Site Profiling function to develop and maintain a treatment center segmentation and prioritization model to guide activation strategy based on capacity, market opportunity, and readiness.
- Cross-Functional Collaboration
- Serve as the lead for treatment center onboarding within cross-functional forums, including Commercial, Medical Affairs, Regulatory, Quality, and Operations.
- Oversee the accurate definition and integration of onboarding workflows in the ordering and CRM systems.
- Team Leadership & Development
- Lead and mentor a growing team responsible for onboarding and institutional support functions.
- Design lean, efficient team structures and workflows that maximize onboarding effectiveness and enable scalable support for post-launch growth.
Qualifications
- A minimum of 8-10 years of experience in site onboarding, market enablement, institutional engagement, commercial operations, or related functions within biotech/pharma; oncology, hematology, or cell therapy experience strongly preferred.
- Proven track record in designing and executing treatment center onboarding frameworks for complex therapies (e.g., CAR-T, allogeneic transplant, gene therapy), including certification, training, and operational readiness programs.
- Demonstrated success in launching new products and entering new markets, with deep knowledge of commercial strategy, sales execution, and market development for advanced therapies.
- Hands-on experience working with commercial operations, sales, and marketing teams to align onboarding strategies with broader commercial objectives, messaging, and field execution.
- Track record of collaborating cross-functionally across clinical, regulatory, medical, supply chain, and quality functions to ensure institutional readiness and compliance.
- Strong commercial acumen and execution mindset; able to translate strategic goals into actionable and measurable plans.
- Excellent communication, project management, and engagement skills, with the ability to influence across internal teams and external institutions.
- Leadership experience managing direct reports and/or cross-functional teams, with a demonstrated ability to build and develop high-performing teams.
- Thrives in fast-paced, evolving environments requiring agility, problem-solving, and prioritization under pressure.
Who we are
We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all who need them.
We live by our core values of passion, courage, and integrity. Excellence in our work means the chance to unlock a better quality of life for our patients, and with that comes tremendous responsibility.
We innovate on a path that hasn’t been paved. We embrace an entrepreneurial spirit and take calculated risks to achieve our mission. We aren’t afraid to ask “why not” and challenge the status quo.
We maintain a start-up culture of camaraderie and leadership by example, regardless of title.
We’re proud to be an equal opportunity employer, and recognize that celebrating our differences creates stronger, lasting solutions that better serve our team, our patients and their healthcare providers.
Notice to staffing firms
Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent team, and all candidates are presented through this channel only. We do not accept unsolicited resumes, and we rarely outsource recruitment.
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