Head of Sales

Own the Playbook. Win the Logos. Build the GTM.

Helical is building the AI-native lab for biology; replacing slow, costly wet lab experimentation with scalable, virtual discovery. Our platform is already deployed with leading global pharma, enabling teams to run millions of experiments in days, not years.

We have product-market traction. Now we’re scaling and looking for someone to build and lead that journey.

We’re hiring a Head of Sales to own new business and build Helical’s commercial function from the ground up.

This is a player-coach role. You’ll be responsible for closing high-value deals yourself, while also shaping how we go to market; defining the playbook, building pipeline, and laying the foundations for a high-performing commercial team.

This is not a “manage and inherit” role. This is build, sell, and scale.

Win New Business

• Land new logos across top pharma and large biotech
• Own the full sales cycle from prospecting to close
• Navigate complex, multi-stakeholder deals with scientific buyers
• Turn initial deals into long-term, multi-program partnerships

Build the GTM Engine

• Define and execute the go-to-market strategy
• Build repeatable pipeline, qualification, and forecasting processes
• Implement AI-first sales workflows across prospecting and pipeline management
• Hire, mentor, and scale the early commercial team

Drive Strategic Growth

• Develop partnerships across pharma, tech, and research ecosystems
• Expand Helical’s footprint through high-value relationships and collaborations

Be the Market Face

• Represent Helical with credibility at key industry events and conferences
• Build relationships with decision-makers in discovery, computational biology, and AI

Who You Are

• Proven track record of closing complex enterprise deals and winning new logos
• Experience building GTM and sales functions from scratch (early-stage environments)
• Strong ability to sell into technical and scientific stakeholders
• Comfortable operating in ambiguity and owning outcomes end-to-end
• AI-first mindset—you leverage AI across your workflows to drive better results
• Deep interest in how AI is transforming drug discovery

• Proven product already in use with top pharma
• Opportunity to shape a category-defining company at an inflection point
• High ownership, direct impact, and close collaboration with founders
• Clear trajectory to CRO / full commercial leadership
• Competitive Salary, Equity and Benefits