Praxis Precision Medicines, Inc. Logo

Praxis Precision Medicines, Inc.

Director, Commercial FP&A

Reposted 8 Days Ago
Be an Early Applicant
Easy Apply
Remote
Hiring Remotely in United States
200K-220K Annually
Senior level
Easy Apply
Remote
Hiring Remotely in United States
200K-220K Annually
Senior level
The Director of Commercial FP&A leads financial planning and analysis for a commercial organization, focusing on launch readiness, revenue forecasting, and strategic finance partnerships with cross-functional teams.
The summary above was generated by AI

Location:  This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Opportunity

Praxis Medicines is seeking a Commercial FP&A leader to serve as a strategic finance partner to our Commercial organization as we prepare for launch and scale toward a multi-billion-dollar revenue organization. This role will support near-term launch readiness while also building the financial capabilities, discipline and insights required to operate at commercial scale over time.
This role sits within Finance but works in close, real-time partnership with Commercial, CMC and other cross-functional teams. The successful candidate will be deeply embedded in ongoing commercial workstreams, enabling forward-looking decision-making through continuous engagement rather than periodic reporting.

Primary Responsibilities

  • Act as the primary FP&A partner to Commercial leadership, supporting brand strategy, launch planning and revenue forecasting from pre-launch through scale.
  • Perform revenue modeling, scenario and sensitivity analyses and key commercial assumptions as the business grows to multi-billion-dollar revenue levels.
  • Partner closely with CMC and Supply Chain teams on inventory assumptions, demand planning and working capital considerations.
  • Collaborate cross-functionally on pricing, gross-to-net, market access and demand dynamics.
  • Lead Commercial and CMC input into budgets, ongoing forecasts and long-range plans.
  • Evaluate investment decisions through ROI analysis and financial modeling to support prioritization and resource allocation.
  • Develop executive-ready materials that clearly communicate risks, opportunities and trade-offs.
  • Continuously improves forecasting tools, processes and analytical rigor to support a scaling commercial organization.

Qualifications and Key Success Factors

  • 12–15+ years of experience in FP&A or strategic finance, with strong commercial exposure
  • Biopharma experience required, including experience supporting a commercial-stage company
  • Experience supporting product launch and operating in a scaled commercial environment preferred
  • Advanced financial modeling and analytical skills
  • Proven ability to influence and partner with senior stakeholders across Finance, Commercial and CMC
  • Strong business judgment and executive communication skills
  • Comfortable operating in a fast-paced, evolving environment with ambiguity
  • The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement.  You'll need comfort with screen work, basic hand coordination, and focus.  Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.


Compensation & Benefits

At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive.  This includes 99% of the premium paid for medical, dental and vision plans.  We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future?  We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP.  We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns.  Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring.  We aim high, collaborate hard, and produce results.  Let’s achieve the impossible together! 

To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below.  Final salary range may be modified commensurate with job level, education, and experience.

Annualized Base Salary
$200,000$220,000 USD

Company Overview 

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance.  At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders.  Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.
Diversity, Equity & Inclusion
Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.
Attention: Job Scam Alert
Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to [email protected].
Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.

Top Skills

Analytical Skills
Budgeting
Commercial Strategy
Financial Modeling
Forecasting
HQ

Praxis Precision Medicines, Inc. Boston, Massachusetts, USA Office

99 High St, Boston, MA , United States, 02110

Similar Jobs

10 Days Ago
Remote
USA
154K-193K Annually
Expert/Leader
154K-193K Annually
Expert/Leader
Biotech • Pharmaceutical
Lead commercial FP&A for forecasting, gross-to-net, expense planning, and performance analysis. Partner with Commercial, Accounting, NPP, and S&OP to drive forecast accuracy, ROI analysis, purchase order controls, and strategic financial recommendations for senior leadership.
Top Skills: Workday Adaptive Planning
3 Days Ago
Easy Apply
Remote
United States
Easy Apply
172K-230K Annually
Senior level
172K-230K Annually
Senior level
AdTech • Artificial Intelligence • Big Data • Machine Learning • Marketing Tech • Mobile • Software
The Director, Commercial FP&A leads the FP&A team, providing financial insights and driving decision-making for business growth and revenue reporting.
Top Skills: Data VisualizationFinancial ModelingForecasting Systems
20 Minutes Ago
Remote or Hybrid
San Francisco, CA, USA
Mid level
Mid level
Artificial Intelligence • Fintech • Payments • Business Intelligence • Financial Services • Generative AI
The Recruiter will manage full-cycle recruiting for GTM and Corporate roles, collaborating with hiring managers, sourcing candidates, and negotiating offers.
Top Skills: Applicant Tracking SystemAshby

What you need to know about the Boston Tech Scene

Boston is a powerhouse for technology innovation thanks to world-class research universities like MIT and Harvard and a robust pipeline of venture capital investment. Host to the first telephone call and one of the first general-purpose computers ever put into use, Boston is now a hub for biotechnology, robotics and artificial intelligence — though it’s also home to several B2B software giants. So it’s no surprise that the city consistently ranks among the greatest startup ecosystems in the world.

Key Facts About Boston Tech

  • Number of Tech Workers: 269,000; 9.4% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Thermo Fisher Scientific, Toast, Klaviyo, HubSpot, DraftKings
  • Key Industries: Artificial intelligence, biotechnology, robotics, software, aerospace
  • Funding Landscape: $15.7 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Summit Partners, Volition Capital, Bain Capital Ventures, MassVentures, Highland Capital Partners
  • Research Centers and Universities: MIT, Harvard University, Boston College, Tufts University, Boston University, Northeastern University, Smithsonian Astrophysical Observatory, National Bureau of Economic Research, Broad Institute, Lowell Center for Space Science & Technology, National Emerging Infectious Diseases Laboratories

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account