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Bristol Myers Squibb

Associate Director/Director, Translational Development

Posted 19 Days Ago
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Cambridge Crossing, City of Boston, MA
Expert/Leader
Cambridge Crossing, City of Boston, MA
Expert/Leader
Lead scientific and preclinical laboratory components for late stage hematology programs, guiding a team in mechanism of action studies and clinical development support.
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Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.


Bristol-Myers Squibb is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health.  We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

BMS R&D is at a critical and exciting phase of development. As it expands and integrates its portfolio including small molecules, biologics and cell therapies, there is an opportunity for a dynamic and resourceful individual to lead a team of innovative laboratory scientists that are addressing scientific questions in support of programs managed by the Translational Development group. 

Translational Development at BMS 

Translational Development is part of the Global Research organization in BMS and leads late stage clinical, pharmacological and translational research and development activities for the pipeline and supports late stage portfolio for regulatory, translational development and life cycle management. Translational Development drives strategy across core therapeutic areas at BMS including hematology, oncology, immunology, cardiovascular and neuroscience. This group integrates laboratory science, clinical trial/biomarkers and asset development as well as disease research to maximize the potential of BMS current and future therapeutics. 

Summary

Reporting to Executive Director, Translational Development, the incumbent will be part of the translational group based in Cambridge, MA and will manage the scientific and preclinical laboratory component of multiple late stage hematology programs (phase 2 and beyond). Key responsibilities of this role are to serve as a key scientific lead for the preclinical support of asset programs through mechanism of action-based studies, differentiation from standard of care molecules, combination rationale and resistance mechanisms. Incumbent will work with translational scientists, disease leaders within translational medicine and thematic research centers in early development within the company. In addition, guidance of laboratory scientists to generate data in support of clinical development decisions will be required. In addition, this position will have 3+ direct reports and therefore guidance to generate data in support of Heme Translational Medicine goals will be required.

Responsibilities

  • Leads a group of scientists who execute the preclinical/laboratory support component of late stage BMS portfolio of compounds to support annual goals and objectives for the Heme translational medicine group (for internal /external, collaborations, compound specific plans etc). 
  • Responsible for delivering data in support of translational strategies including biomarkers, patient selection hypotheses, dose and schedule, combination strategies, resistance mechanisms and differentiation
  • Report directly to the Executive Director and manages laboratory scientists to integrate clinical questions into lab-based translational research internally and externally
  • Interfaces with early development scientist to ensure seamless flow of information for assets which are entering the remit of translational medicine
  • Manages and supervises a portfolio of preclinical collaborations across the pipeline compounds for clinical assets 
  • Assists in managing key strategic and/or collaborative projects along with TD asset-facing scientists 
  • Communicates regularly and prepares and makes presentations within the department, externally and to senior management as required
  • Assists in developing and maintaining group budget and workforce plan 

Qualifications

  • PhD or MD/PhD with at least 10 years of relevant work experience. Experience including drug development in an industry setting, especially in heme-onc, immunology or neuroscience.
  • Strong publication record and track record in large and/or small companies, leading innovative efforts within the laboratory setting to achieve defined goals and support clinical development
  • Excellent communication, managerial and scientific qualities are expected
  • Ability to interact effectively across boundaries using influencing and relationship building skills.
  • Competence in analysis and solving of problems, and the ability to prioritize and make tradeoffs to achieve goals.

Technical Skills

  • In-depth understanding of cancer biology, immunology and/or neuroscience clinical landscape, evolving technologies, competitive scenario
  • Good understanding of drug development process in an industry setting with clear examples of success
  • Understanding of late-stage drug and translational development process
  • Ability to work with disease teams/experts to develop preclinical strategies to support clinical development and life cycle management
  • Strong verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications/reviews, disease strategies, mechanism slides, regulatory submissions, and strategic communications
  • Proven scientific/project leadership expertise (working in teams, managing collaborations, people/projects)
  • Basic understanding of IP, contracting terms and provisions  

Other Attributes

  • A problem solver who creatively and knowledgeably transcends departmental function to act as a resource to entire research effort and senior managers in development. 
  • Identifies issues early and proposes innovative solutions.
  • Communicates within the larger organization and external community.
  • Provides expert guidance to multi-disciplinary teams and senior management.
  • A leader whose scope of influence stretches across the company
  • A leader who influences external scientific community.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Top Skills

Cancer Biology
Drug Development
Immunology
Neuroscience

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