Senior Manager or Associate Director, Statistical Programming

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn. 

• PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
• COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
• BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.

Kymera Therapeutics is seeking an experienced and strategic Associate Director of Statistical Programming to lead programming efforts across multiple clinical studies. This role will be instrumental in ensuring high-quality, timely, and compliant statistical deliverables in support of Kymera’s innovative degrader pipeline. The ideal candidate will bring deep technical expertise in SAS programming, CDISC standards, and regulatory submission readiness, along with strong leadership and vendor oversight capabilities.

• Lead across multiple studies or a clinical program, ensuring timely, accurate, and regulatory-compliant deliverables, including oversight of SDTM, ADaM, and TLF deliverables by vendors.
• Collaborate closely with internal study team and external partners to ensure alignment on timelines, priorities, and quality expectations.
• Oversee CRO deliverables as needed, with a focus on technical quality and consistency, ensuring clear documentation of the process
• Develop, validate, and maintain datasets (SDTM, ADaM), tables, listings, and figures, TLFs) in accordance with regulatory guidelines and internal standards to assist with data review, CSR, annual data report, publication, in-house data request, etc
• Provide expertise in statistical programming for regulatory submissions (e.g., FDA, EMA), including electronic submission standards (eCTD)
• Coordinate and schedule data transfers and delivery of required outputs as the lead or support programmer on studies
• Review key clinical study or program documents
• Manage multiple tasks, troubleshoot technical and project issues, and assist with the infrastructure development of the department; Evaluate and implement innovative tools and programming technologies to streamline processes and improve team efficiency and quality
• Stay current with industry trends, best practices, and emerging technologies in statistical programming and data analysis

• MS or equivalent degree in Statistics, Biostatistics, Computer Science, or related field.
• 8+ years of experience in statistical programming in the pharmaceutical or biotech industry. (7+ years of experience for Senior Manager)
• Deep understanding and hands-on experience with CDISC standards (SDTM, ADaM) and regulatory submission requirements
• Proven ability to independently produce high-quality analysis datasets, tables, listings, and figures for data request.
• Possess significant expertise in SAS and clinical trial programming including data steps, procedures, SAS/MACRO, SAS/GRAPH and programming expertise with clinical endpoint data (efficacy and safety) and PK/PD data
• Demonstrated ability to collaborate effectively in cross-functional settings and manage competing priorities in a fast-paced or startup environment
• Excellent communication, leadership, and project management skills.
• R or Python is plus

Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment.  All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.