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Bristol Myers Squibb

Associate Director, Early Translational Informatics and Predictive Sciences - Neuroscience Lead

Posted 8 Days Ago
Be an Early Applicant
2 Locations
212K-257K Annually
Senior level
2 Locations
212K-257K Annually
Senior level
Lead a team of computational scientists in developing biomarker strategies, analyzing clinical trial data, and guiding drug development for neurodegenerative disorders.
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Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Associate Director, Early Translational Informatics and Predictive Sciences - Neuroscience Lead

When you join BMS, you are joining a diverse, high-achieving team united by a common mission. 

The Informatics and Predictive Sciences (IPS) mission is to Pioneer, Partner and Predict to drive transformative insights for patient benefit.  IPS conducts applied computational research in areas that include genomic, structural and molecular informatics, computational and systems biology, patient selection and translational biomarker research, and broader fields including knowledge science, epidemiology and machine learning—across the full lifecycle of drug discovery and development and across all therapeutic areas at BMS.   We do this in close partnership with scientific and clinical experts in the field, both inside and outside the company.   We perform innovative science to empower key data-driven decisions across a rich pipeline of next-generation medicines. In doing so, our work transforms the lives of patients, as well as our own lives and careers.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

We seek a creative and passionate computational scientist with a background in addressing neuroscience translational questions to lead the Neuroscience Early Translational team within Informatics and Predictive Sciences, a globally distributed group driving innovative computational research for discovery and early development. In this role, you will lead a team of skilled computational scientists analyzing high-dimensional readouts from longitudinal patient cohorts and early clinical trials. You will implement rigorous data analysis practices and align resources based on scientific priorities, enabling the next wave of breakthrough therapies to reach patients faster through innovative clinical trial designs.

Responsibilities

  • Lead a team of PhD level scientists to develop target engagement and pharmacodynamic biomarker hypotheses, collaborate with translational scientists to develop biomarker plans, and analyze biomarker data from early clinical trials
  • Develop analytic strategies to identify novel biomarker approaches for patient stratification, disease mechanism understanding, and surrogate measures and lead within a larger team of informatics and predictive scientists to execute these strategies and analysis plans
  • Work collaboratively with translational teams to extract insights, generate hypotheses and guide drug development decisions in early clinical development of new therapeutics targeting neurodegenerative and neuropsychiatric disorders.

Basic Qualifications:

  • Bachelor's Degree 12+ years of academic / industry experience
  • Or Master's Degree 10+ years of academic / industry experience
  • Or PhD 8+ years of academic / industry experience
  • 4+ years of leadership experience

Preferred Qualifications:

  • Ph.D. in bioinformatics, computational biology, statistics, or a similar discipline.
  • Eight or more (8+) years of relevant experience in translational or clinical research.
  • Four or more (4+) years of leadership experience managing PhD-level scientists
  • Demonstrated expertise in neuroscience drug development and cutting-edge approaches for molecular/imaging/digital biomarkers and clinical trial design
  • Proficiency using R and 1+ additional programming language with a strong background in -omic (DNA, RNA, epigenetic, proteomic) data analysis and biological interpretation.
  • Strong experience in statistical modeling and/or machine learning approaches, such as mixed-effects models, predictive modeling, etc. to represent biological concepts.
  • Experience with clinical database (SDTM/ADaM) and biomarker statistical analysis.
  • Demonstrated ability to communicate effectively within cross-functional teams

The starting compensation for this job is a range from $212,000 - $257,000, plus incentive cash and stock opportunities (based on eligibility). The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience. For more on benefits, please visit our BMS Careers site. Eligibility for specific benefits listed in our careers site may vary based on the job and location.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.  

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Top Skills

Bioinformatics
Biomarker Statistical Analysis
Clinical Databases
Computational Biology
Machine Learning
Programming Languages
R
Statistical Modeling

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