Jobs at Dyne Therapeutics

Leads market research and competitive intelligence for Duchenne muscular dystrophy and myotonic dystrophy therapies. Designs qualitative and quantitative research, integrates findings with secondary data, manages vendors, assesses competitive dynamics, supports commercial strategy, and delivers executive-ready insights. Partners cross-functionally across Commercial, Medical, Clinical, Regulatory, Finance, and Business Development, while facilitating scenario planning and congress intelligence activities in a compliant biotechnology environment.

Leads financial planning, budgeting, forecasting, reporting, scenario modeling, and decision support for Research and Development. Partners with executives and R&D leaders on clinical trial forecasting, portfolio investment, resource allocation, cash runway, and operating performance. Oversees financial models, dashboards, actuals reporting, accrual support, controls, and process improvements while ensuring alignment with US GAAP and SOX. Builds and develops FP&A talent and presents executive-level recommendations.

Provides high-level administrative and operational support to the SVP and US Affiliate Leadership Team. Responsibilities include complex calendar management, meeting and event coordination, travel arrangements, expense reporting, document preparation, action-item tracking, cross-functional coordination, budget and invoice support, and process improvement. The role requires discretion, sound judgment, strong organization, and proactive management of executive and affiliate operations.

Provides strategic administrative and operational support to senior executives, managing complex calendars, domestic and international travel, meetings, events, communications, expenses, board activities, and cross-functional initiatives. Coordinates leadership operations, tracks priorities and deliverables, supports governance and organizational effectiveness, and serves as a trusted liaison to internal and external stakeholders. Requires exceptional judgment, discretion, organization, communication, and proficiency with Microsoft Office tools.

Leads Quality Control strategy and execution for clinical and commercial manufacturing, ensuring GMP compliance, inspection readiness, analytical method lifecycle management, release and stability testing, specifications, investigations, data integrity, and external laboratory performance. Oversees regulatory CMC submissions, vendor partnerships, QC capabilities, and team development across a matrixed biotechnology organization.

Designs, synthesizes, purifies, characterizes, and optimizes protein, peptide, antibody, and oligonucleotide bioconjugates for therapeutic programs. Develops linker and site-specific conjugation strategies, analyzes experimental data, troubleshoots technical challenges, documents findings, and collaborates cross-functionally across chemistry, protein engineering, analytical sciences, biology, and process development. Supports technology innovation and transfer of conjugation processes to development and manufacturing teams.

The Director oversees and evolves the Quality Management System, embedding quality in operations and ensuring compliance with global regulations while managing audits and supplier quality.

Lead and execute HR operations strategy and day-to-day functions including onboarding, HRIS administration, benefits, compliance, vendor management, reporting, automation, and process improvement. Serve as HR technology and data governance owner, partner cross-functionally, manage immigration and benefits processes, and lead, coach, and scale the People Operations team to support growth and commercialization readiness.

The Senior Director of Program Management leads cross-functional teams in drug development, ensuring strategic alignment and execution while fostering collaboration and continuous improvement.

Lead Talent Acquisition operations, systems, programs, and reporting to scale hiring. Own ATS and integrations, design recruiting processes and governance, improve candidate and hiring-team experience, drive TA analytics and dashboards, ensure compliance, manage vendors and budgets, and partner cross-functionally to implement TA technology, automation, and continuous process improvements.

Partnering directly with the CCO, lead high-priority commercial strategy and cross-functional initiatives, shape the commercial operating model, prepare executive and Board materials, and drive decision-making and execution to support launch and growth of rare-disease therapeutics.

Senior HR leader responsible for enterprise learning, leadership development, manager excellence, onboarding, succession planning, and workforce capability. Partners with executive teams to design scalable blended learning, measure impact with analytics, drive culture and change initiatives, and build a high-performing L&D function to support Dyne's growth.

The Director of HCP Marketing leads strategies for engaging healthcare providers in Duchenne Muscular Dystrophy, focusing on launch execution, cross-functional collaboration, and utilizing insights for improved performance.

Lead Dynes enterprise procurement function, building source-to-pay strategy, processes, systems, and supplier management. Drive high-value sourcing, negotiations, compliance, cross-functional partnership, reporting on savings and risks, and CSR/ESG procurement initiatives to support growth and operational goals.

Lead design, scaling, and governance of a global, inspection-ready Quality Management System (QMS) supporting commercial readiness. Own document control, records management, training/eDMS/LMS, eQMS implementation, compliance with ICH/FDA/EU standards, inspection readiness, quality metrics, and cross-functional embedding of quality practices.

The Director of QA GMP Operations manages GMP quality for external and internal manufacturing, overseeing quality assurance activities and compliance. Responsibilities include managing deviations, QA support for tech transfer, and fostering collaboration across various teams.